Development Level

Tbio 17 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

hemorrhage 23 | 23
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 16 | 11,493
osteosarcoma 14 | 7,950
ovarian cancer 13 | 8,520
medulloblastoma, large-cell 9 | 6,241
lung cancer 8 | 4,740
Cancer 7 | 2,499
glioblastoma 6 | 5,792
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
psoriasis 6 | 6,694
Kidney cancer 5 | 2,613
astrocytic glioma 5 | 2,597
atypical teratoid / rhabdoid tumor 5 | 5,112
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
oligodendroglioma 5 | 2,850
Breast cancer 4 | 3,578
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Amyotrophic lateral sclerosis 3 | 451
Astrocytoma, Pilocytic 3 | 3,081
Cerebrovascular disease 3 | 238
Schizophrenia 3 | 1,160
acute myeloid leukemia 3 | 783
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Acquired metabolic disease 2 | 336
Breast Neoplasms 2 | 445
Congestive heart failure 2 | 113
Decreased tendon reflex 2 | 122
Heart failure 2 | 162
Hydrolethalus syndrome 2 | 128
Hyperhidrosis disorder 2 | 81
Increased sweating 2 | 81
Liver cancer 2 | 604
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Myopathy 2 | 185
Neurodegenerative disease 2 | 414
Pick disease 2 | 1,894
Skin cancer 2 | 469
Sweating 2 | 81
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
head and neck cancer 2 | 271
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
posterior fossa group B ependymoma 2 | 416
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Abnormal brain FDG positron emission tomography 1 | 9
Acute coronary syndrome 1 | 39
Behavioral variant of frontotemporal dementia 1 | 8
Blood Platelet Disorders 1 | 3
Bone Diseases, Developmental 1 | 27
Compulsive hoarding 1 | 7
Developmental arithmetic disorder 1 | 8
Difficulty making arithmetical calculations 1 | 8
Dysphasia 1 | 23
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Familial isolated dilated cardiomyopathy 1 | 41
Frontotemporal cerebral atrophy 1 | 8
Hemorrhage 1 | 19
Hyperorality 1 | 7
Hyperphagia 1 | 23
Increased appetite (finding) 1 | 23
Jaw Abnormalities 1 | 5
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Lower Extremity Deformities, Congenital 1 | 2
Onion bulb formation 1 | 19
Paroxysmal supraventricular tachycardia 1 | 12
Peg-shaped teeth 1 | 8
Pointed teeth 1 | 8
Prevention of Paroxysmal Supraventricular Tachycardia 1 | 4
Repeated speech 1 | 9
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Liver and Pancreas 21 | 16,750
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 5 | 4,145
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 PYROXD1 Tdark Enzyme 0.36 0.20 47
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79
Metal regulatory transcription factor 1 MTF1 Tbio Transcription Factor -1.98140 101.0 135
SNARE-associated protein Snapin SNAPIN Tbio Non-IDG -1.65821 50.9 69
Myosin-10 MYH10 Tbio Non-IDG -1.77478 55.4 94
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Proprotein convertase subtilisin/kexin type 5 PCSK5 Tchem Enzyme -2.88342 751.2 143
Histone-lysine N-methyltransferase EHMT2 EHMT2 Tchem Epigenetic -2.49970 327.4 277
B-cell lymphoma/leukemia 11B BCL11B Tbio Transcription Factor -2.10918 140.4 186
Ras GTPase-activating protein 3 RASA3 Tbio Enzyme -1.57479 40.8 225