Development Level

Tbio 4 | 11,445
Tdark 2 | 6,588
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

fusion of vertebral arches 7 | 7
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
psoriasis 5 | 6,694
Carcinoma 4 | 11,493
glioblastoma 4 | 5,792
lung carcinoma 4 | 2,843
osteosarcoma 4 | 7,950
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
subependymal giant cell astrocytoma 3 | 2,287
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Kidney cancer 2 | 2,613
Rheumatoid arthritis 2 | 1,191
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
Acne 1 | 52
Advanced bone age 1 | 35
Alzheimer's disease 1 | 658
Amenorrhea 1 | 58
Androgen insensitivity syndrome 1 | 12
Anovulation 1 | 21
Arthritis, Rheumatoid 1 | 174
Barrett's esophagus 1 | 182
Becker muscular dystrophy 1 | 191
Breast cancer 1 | 3,578
Colorectal Neoplasms 1 | 243
Congenital adrenal hyperplasia 1 | 73
Disease Progression 1 | 136
Disorders of Sex Development 1 | 5
Duchenne muscular dystrophy 1 | 601
ENSP00000256078 1 | 30
Elevated gonadotropins 1 | 15
Hair shaft abnormalities 1 | 30
Hypospadias 1 | 53
Increased size of penis 1 | 7
Infertility 1 | 188
Infertility, Male 1 | 46
Kidney disease 1 | 430
Lactocele 1 | 3
Leydig Cell Hypoplasia, Type 1 1 | 2
Leydig cell tumor 1 | 9
Liver Cirrhosis, Experimental 1 | 769
Male infertility 1 | 206
McCune Albright syndrome 1 | 19
Melanoma 1 | 711
Ovarian hyperstimulation syndrome 1 | 19
Polycystic ovary syndrome 1 | 360
Precocious Puberty 1 | 28
Precocious Puberty, Male-Limited 1 | 2
Premature ovarian failure 1 | 65
Primary hypogonadism 1 | 37
Prostatic Neoplasms 1 | 495
Pseudohermaphroditism 1 | 16
Restless legs syndrome 1 | 27
Skin cancer 1 | 469
Small testicle 1 | 75
Stomach Neoplasms 1 | 300
Substance-Related Disorders 1 | 115
Tall stature 1 | 34
Waldenstrons macroglobulinemia 1 | 765
Wiskott-Aldrich syndrome 1 | 30
acute myeloid leukemia 1 | 783
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
esophageal adenocarcinoma 1 | 737
gastric carcinoma 1 | 807
hair abnormalities (non-specific) 1 | 30
interstitial lung disease 1 | 298
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
limb girdle muscular dystrophy 2B 1 | 40
nasopharyngeal carcinoma 1 | 1,058
non diabetic and post-ischemic heart failure 1 | 200
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
permanent atrial fibrillation 1 | 45
primitive neuroectodermal tumor 1 | 3,035
sarcoidosis 1 | 370

Tissue

Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Blood and immune system 6 | 16,909
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393

Target Family

Non-IDG 2 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
AF4/FMR2 family member 3 AFF3 Tbio Transcription Factor -1.37981 25.3 50
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
Lutropin-choriogonadotropic hormone receptor LHCGR Tclin GPCR -2.58909 376.4 243
CSC1-like protein 1 TMEM63A Tdark Ion Channel -0.01424 1.07 53
Actin-related protein 2/3 complex subunit 1B ARPC1B Tbio Non-IDG -1.16868 14.7 136
WD repeat-containing protein 37 WDR37 Tdark Non-IDG 0.41 0.39 106
Deoxyribonuclease-1-like 2 DNASE1L2 Tbio Enzyme -1.67313 48.8 23