Development Level

Tbio 7 | 11,651
Tdark 1 | 6,593

IMPC Phenotype

enlarged urinary bladder 8 | 8
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 7 | 11,493
osteosarcoma 6 | 7,950
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Autosomal recessive predisposition 2 | 1,442
Cognitive delay 2 | 608
Frontal bossing 2 | 157
Global developmental delay 2 | 608
Highly variable severity 2 | 157
Hypogonadism 2 | 173
Mental and motor retardation 2 | 608
Variable expressivity 2 | 157
facioscapulohumeral dystrophy 2 | 288
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
medulloblastoma 2 | 720
ulcerative colitis 2 | 1,819
Accessory rib 1 | 10
BCC1 1 | 3
Barrett's esophagus 1 | 182
Basal Cell Nevus Syndrome 1 | 5
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Brachydactyly 1 | 156
Brain disease 1 | 96
CNS hypomyelination 1 | 17
Calcification of falx cerebri 1 | 6
Carcinoma, Basal Cell 1 | 28
Cardiac fibroma 1 | 3
Cardiac rhabdomyoma 1 | 5
Cerebellar Dysmetria 1 | 56
Cerebral calcification 1 | 43
Class III malocclusion 1 | 78
Conduct disorder 1 | 33
Congenital anomaly of neck 1 | 19
Congenital fusion of ribs 1 | 4
Congenital hemivertebra 1 | 25
Cyclothymic disorder 1 | 8
Cystinuria 1 | 18
Deformity of neck 1 | 19
Deglutition Disorders 1 | 132
Delayed Puberty 1 | 97
Drooling 1 | 27
Fatigue 1 | 182
Fused vertebrae 1 | 25
Gastrointestinal Stromal Tumors 1 | 48
Gilles de la Tourette syndrome 1 | 47
Gorlin syndrome 1 | 4
Hamartomatous stomach polyps 1 | 3
Herpes zoster 1 | 68
Hypernasal voice 1 | 39
Hyperphagia 1 | 23
Hypertrophy of lower jaw 1 | 78
Hypocalcemia 1 | 32
Hypodontia 1 | 81
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypomyelinating leukoencephalopathy 1 | 7
Hypomyelination 1 | 17
Increased appetite (finding) 1 | 23
Increased size of mandible 1 | 78
Irregular ossification of hand bones 1 | 3
Keratocystic Odontogenic Tumor 1 | 3
Kluver-Bucy syndrome 1 | 6
Kyphoscoliosis deformity of spine 1 | 60
Learning disability 1 | 17
Leukodystrophy 1 | 55
Lysinuric protein intolerance 1 | 15
MACROSTOMIA, ISOLATED 1 | 2
Malformation of the neck 1 | 19
Mandibular hyperplasia 1 | 78
Melanocytic nevus 1 | 43
Milium Cyst 1 | 16
Mitochondrial respiratory chain defects 1 | 15
Mucopolysaccharidosis III 1 | 7
Noncancerous mole 1 | 28
Oligodontia 1 | 24
Orbital cyst 1 | 8
Ovarian Fibromata 1 | 3
Palmar pit 1 | 4
Parietal bossing 1 | 5
Plantar pits 1 | 4
Primary hypogonadism 1 | 37
Primary pigmented nodular adrenocortical disease 1 | 13
Recurrent urinary tract infection 1 | 24
Sella Turcica, Bridged 1 | 3
Short 4th metacarpal 1 | 7
Short ribs 1 | 30
Short thumb terminal phalanx 1 | 5
Sialorrhea 1 | 28
Skin tag 1 | 14
Sloping shoulders 1 | 21
Spinal fusion 1 | 25
Sprengel deformity 1 | 16
Static Tremor 1 | 21
Sternal anomalies 1 | 19
Tooth agenesis 1 | 44
Vertebral body fusion 1 | 25
Vertebral wedging 1 | 4
mandibular excess (physical finding) 1 | 78

Tissue

Endocrine System 8 | 18,159
Skin and soft tissues 8 | 17,230
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Urinary Tract 7 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 2 | 4,145
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221
Golgi resident protein GCP60 ACBD3 Tbio Non-IDG -1.30146 23.4 248
Neutral and basic amino acid transport protein rBAT SLC3A1 Tbio Transporter -2.60836 401.8 140
Protein patched homolog 2 PTCH2 Tbio Non-IDG -1.80541 50.4 92
Dysbindin domain-containing protein 2 DBNDD2 Tdark Non-IDG 0.23 0.66 28
Heparan-alpha-glucosaminide N-acetyltransferase HGSNAT Tbio Enzyme -1.43006 29.3 31
DNA-directed RNA polymerase III subunit RPC1 POLR3A Tbio Enzyme -2.25632 178.2 99
Homeobox protein GBX-1 GBX1 Tbio Transcription Factor -1.18074 14.9 100