Development Level

Tbio 6 | 11,445

IMPC Phenotype

enlarged testis 6 | 6
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 3 | 11,493
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Cancer 2 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Alopecia areata 1 | 41
Autosomal recessive predisposition 1 | 1,442
Basal Ganglia Diseases 1 | 14
Celiac disease 1 | 116
Central nervous system disease 1 | 10
Common variable immunodeficiency 1 | 101
Gestational diabetes 1 | 26
Hepatitis B 1 | 108
Hypersensitivity reaction type II disease 1 | 253
IMMUNODEFICIENCY, COMMON VARIABLE, 11 1 | 1
Inflammatory bowel disease 1 | 151
Intellectual disability 1 | 1,016
Learning Disorders 1 | 29
Lupus Erythematosus, Systemic 1 | 67
MICROCEPHALY 15, PRIMARY, AUTOSOMAL RECESSIVE 1 | 1
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 1 | 16
MYOPATHY WITH EXTRAPYRAMIDAL SIGNS 1 | 1
Microcephaly 1 | 166
Movement Disorders 1 | 55
Muscular Diseases 1 | 27
Myopathy 1 | 185
Paraplegia 1 | 74
Pre-Eclampsia 1 | 68
Primary autosomal recessive microcephaly 15 1 | 1
Retinitis pigmentosa Y-linked 1 | 9
Rheumatoid arthritis 1 | 1,191
Secondary progressive multiple sclerosis 1 | 10
Speech Disorders 1 | 58
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
ductal carcinoma in situ 1 | 1,745
ependymoma 1 | 4,679
gastric cancer 1 | 459
group 3 medulloblastoma 1 | 4,104
hepatocellular carcinoma 1 | 547
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
pituitary cancer 1 | 1,972
sarcoidosis 1 | 370
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Male tissues 6 | 17,142
Respiratory system 6 | 16,393
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Nervous System 5 | 16,725
Skin and soft tissues 5 | 17,230

Target Family

Non-IDG 4 | 12,091
Enzyme 2 | 4,145

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-dependent lysophosphatidylcholine symporter 1 MFSD2A Tbio Non-IDG -1.40175 26.3 73
Phospholipid phosphatase 6 PLPP6 Tbio Enzyme -1.30463 23.2 111
Follistatin-related protein 3 FSTL3 Tbio Non-IDG -1.80964 76.6 138
Interleukin-21 IL21 Tbio Non-IDG -2.45295 349.5 631
Calcium uptake protein 1, mitochondrial MICU1 Tbio Non-IDG -2.51836 321.6 110
Katanin p60 ATPase-containing subunit A1 KATNA1 Tbio Enzyme -1.13087 12.1 158