Development Level

Tbio 27 | 11,445
Tdark 8 | 6,588
Tchem 6 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

enlarged spleen 41 | 41
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 29 | 11,493
osteosarcoma 26 | 7,950
ovarian cancer 22 | 8,520
medulloblastoma, large-cell 18 | 6,241
glioblastoma 16 | 5,792
psoriasis 16 | 6,694
lung cancer 15 | 4,740
atypical teratoid / rhabdoid tumor 13 | 5,112
invasive ductal carcinoma 13 | 2,951
ependymoma 12 | 4,679
group 3 medulloblastoma 11 | 4,104
oligodendroglioma 11 | 2,850
Breast cancer 10 | 3,578
adult high grade glioma 10 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
subependymal giant cell astrocytoma 10 | 2,287
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
Kidney cancer 8 | 2,613
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
pituitary cancer 8 | 1,972
Cancer 7 | 2,499
adrenocortical carcinoma 7 | 1,428
group 4 medulloblastoma 7 | 1,855
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
spina bifida 7 | 1,074
Autosomal recessive predisposition 6 | 1,442
Rheumatoid arthritis 6 | 1,191
acute quadriplegic myopathy 6 | 1,158
cystic fibrosis 6 | 1,696
malignant mesothelioma 6 | 3,232
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
Astrocytoma, Pilocytic 4 | 3,081
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
chronic rhinosinusitis 4 | 512
medulloblastoma 4 | 720
primary pancreatic ductal adenocarcinoma 4 | 1,109
Epilepsy 3 | 792
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Nystagmus 3 | 317
Seizures 3 | 596
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
Bladder Neoplasm 2 | 112
Blepharoptosis 2 | 231
Broad flat nasal bridge 2 | 236
Carcinoma, Transitional Cell 2 | 32
Chronic obstructive pulmonary disease 2 | 184
Concave bridge of nose 2 | 195
Congenital Epicanthus 2 | 177
Coronary artery disease 2 | 268
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Duchenne muscular dystrophy 2 | 601
Failure to gain weight 2 | 365
Hyperreflexia 2 | 209
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Long narrow head 2 | 75
Low Vision 2 | 174
Movement Disorders 2 | 55
Multiple Sclerosis 2 | 540
Nasal bridge wide 2 | 236
Neonatal Hypotonia 2 | 64
Neurodegenerative disease 2 | 414
Night Blindness 2 | 101
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Prenatal onset 2 | 139
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Strabismus 2 | 270
Urinary Bladder Neoplasms 2 | 114
Visual Impairment 2 | 174
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic lymphosyte leukemia 2 | 204
gastric carcinoma 2 | 807
nasopharyngeal carcinoma 2 | 1,058
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735

Tissue

Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Blood and immune system 40 | 16,909
Nervous System 40 | 16,725
Respiratory system 40 | 16,393
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 22 | 12,091
Enzyme 10 | 4,145
Kinase 4 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Ion Channel 1 | 344
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cysteine-rich hydrophobic domain-containing protein 2 CHIC2 Tbio Non-IDG -2.12710 132.1 97
Probable E3 ubiquitin-protein ligase MID2 MID2 Tbio Enzyme -2.49198 303.4 152
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Glutathione S-transferase C-terminal domain-containing protein GSTCD Tbio Enzyme -0.63267 3.65 59
Matrix metalloproteinase-15 MMP15 Tchem Enzyme -1.69065 43.4 351
Zinc finger BED domain-containing protein 4 ZBED4 Tdark Transcription Factor -0.69716 4.10 5
BICD family-like cargo adapter 1 BICDL1 Tdark Non-IDG -0.04139 0.95 14
BTB/POZ domain-containing protein 16 BTBD16 Tbio Non-IDG 0.14 0.32 68
Histone-lysine N-methyltransferase 2C KMT2C Tbio Epigenetic -1.87625 76.5 68
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 B3GNT7 Tdark Enzyme -0.65190 4.07 79