Development Level

Tbio 8 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

enlarged seminal vesicle 10 | 10
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 7 | 8,520
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
Carcinoma 4 | 11,493
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
cutaneous lupus erythematosus 3 | 1,057
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735
Multiple myeloma 2 | 1,332
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
gastric cancer 2 | 459
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Animal Mammary Neoplasms 1 | 136
Autistic Disorder 1 | 364
Basal cell carcinoma 1 | 54
Becker muscular dystrophy 1 | 191
Benign neonatal seizures 1 | 4
Bipolar Disorder 1 | 666
Calcium pyrophosphate deposition disease 1 | 13
Diabetes Mellitus, Experimental 1 | 108
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Duchenne muscular dystrophy 1 | 601
Eaton-Lambert syndrome 1 | 40
Endometriosis 1 | 540
Episodic ataxia 1 | 22
Gilles de la Tourette syndrome 1 | 47
Hemophagocytic lymphohistiocytosis 1 | 30
Hypercalcemia 1 | 59
Hypermagnesemia 1 | 2
Hypocalciuria 1 | 4
Hypoparathyroidism 1 | 41
Ichthyosis 1 | 56
Lens subluxation 1 | 12
Lipoma 1 | 32
Liver Cirrhosis, Experimental 1 | 769
Lupus erythematosus 1 | 57
Major Depressive Disorder 1 | 301
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Multiple Sclerosis 1 | 540
Multiple lipomata 1 | 7
Neurofibromatosis 1 | 40
Nonorganic psychosis 1 | 84
Nuclear cataract 1 | 19
Nuclear non-senile cataract 1 | 18
Pancreatitis 1 | 123
Pellagra 1 | 26
Photosensitive trichothiodystrophy 1 | 30
Presbyopia 1 | 20
Primary hyperparathyroidism 1 | 5
Psychotic Disorders 1 | 151
Secondary progressive multiple sclerosis 1 | 10
Type 2 diabetes mellitus 1 | 272
Unipolar Depression 1 | 250
Uterine fibroid 1 | 28
Vasospasm, Intracranial 1 | 5
Xeroderma pigmentosum group B 1 | 20
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
cystic fibrosis and chronic rhinosinusitis 1 | 214
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
limb girdle muscular dystrophy 2A 1 | 213
mucosa-associated lymphoid tissue lymphoma 1 | 484
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
spina bifida 1 | 1,074
tuberculosis 1 | 2,010
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 10 | 16,909
Endocrine System 10 | 18,159
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 3 | 4,145
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phospholipid phosphatase 6 PLPP6 Tbio Enzyme -1.30463 23.2 111
Protein EVI2B EVI2B Tbio Non-IDG -0.75260 5.34 126
Protein S100-A6 S100A6 Tbio Non-IDG -2.72619 530.5 328
Transmembrane emp24 domain-containing protein 10 TMED10 Tbio Non-IDG -1.46644 31.9 300
AP-2 complex subunit sigma AP2S1 Tbio Non-IDG -1.42073 25.5 108
Filensin BFSP1 Tbio Non-IDG -2.11395 128.7 179
Tryptophan 2,3-dioxygenase TDO2 Tchem Enzyme -2.89113 773.6 193
M-phase-specific PLK1-interacting protein MPLKIP Tbio Enzyme -1.74631 53.5 50
Potassium voltage-gated channel subfamily A member 10 KCNA10 Tclin Ion Channel -1.09844 13.3 65
Tumor necrosis factor receptor superfamily member 17 TNFRSF17 Tbio Non-IDG -2.74787 537.8 430