Development Level

Tbio 1 | 11,651
Tclin 1 | 612

IMPC Phenotype

enlarged liver 2 | 2
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Atopic dermatitis 2 | 952
Breast cancer 2 | 3,578
Carcinoma 2 | 11,493
Insulin Resistance 2 | 72
Kidney cancer 2 | 2,613
Obesity 2 | 678
atypical teratoid / rhabdoid tumor 2 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Abnormal hypothalamus morphology 1 | 3
Absence of secondary sex characteristics 1 | 22
Acquired metabolic disease 1 | 336
Advanced bone age 1 | 35
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Albuminuria 1 | 21
Anorexia nervosa 1 | 80
Breast Neoplasms 1 | 445
Cancer 1 | 2,499
Cardiovascular system disease 1 | 246
Decreased T cell activation 1 | 4
Decreased testosterone in males 1 | 28
Delayed Puberty 1 | 97
Diabetes Mellitus, Experimental 1 | 108
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Diabetic Neuropathies 1 | 14
Diarrhea 1 | 253
Down syndrome 1 | 499
Dyslipidemias 1 | 27
Endocrine System Diseases 1 | 11
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Female infertility 1 | 30
Fibrosis 1 | 44
Gas gangrene 1 | 17
Gaucher disease type 1 1 | 180
Gestational diabetes 1 | 26
Glucose Intolerance 1 | 19
Granulosa cell tumor 1 | 6
Gynecomastia 1 | 64
Hepatitis 1 | 67
Hepatitis B 1 | 108
Hepatomegaly 1 | 285
Hyperglycemia 1 | 137
Hyperinsulinism 1 | 133
Hyperlipidemia 1 | 43
Hyperlipidemias 1 | 17
Hyperphagia 1 | 23
Hypertension 1 | 396
Hypertriglyceridemia result 1 | 37
Immunologic Deficiency Syndromes 1 | 113
Impaired glucose tolerance 1 | 28
Inborn Errors of Metabolism 1 | 16
Increased appetite (finding) 1 | 23
Infertility 1 | 188
Infertility, Female 1 | 28
Insulin resistant diabetes 1 | 13
Insulinoma 1 | 24
Isolated cleft palate 1 | 4
Isolated somatotropin deficiency 1 | 30
Kidney Diseases 1 | 114
Liver Cirrhosis 1 | 181
Low serum estradiol levels 1 | 22
Lung Neoplasms 1 | 232
Mammary Neoplasms 1 | 425
Metabolism, Inborn Errors 1 | 17
Mood swings 1 | 77
Physical aggression 1 | 76
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Recurrent upper respiratory tract infection 1 | 21
Respiratory Tract Infections 1 | 7
Secondary hypothyroidism 1 | 15
Small testicle 1 | 75
adrenocortical carcinoma 1 | 1,428
colon cancer 1 | 1,478
fascioscapulohumeral muscular dystrophy 1 | 100
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
non-small cell lung cancer 1 | 2,890
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
tuberculosis 1 | 2,010
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 1 | 4,145
Non-IDG 1 | 12,091

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Carboxypeptidase E CPE Tbio Enzyme -3.01460 1019.8 229