Development Level

Tbio 66 | 10,625
Tdark 22 | 7,003
Tchem 15 | 1,890
Tclin 8 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

enlarged heart 111 | 111
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 60 | 8,484
psoriasis 48 | 6,685
osteosarcoma 45 | 7,933
lung cancer 43 | 4,466
medulloblastoma, large-cell 41 | 6,234
glioblastoma 40 | 5,572
non-small cell lung cancer 26 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
lung carcinoma 25 | 2,844
atypical teratoid / rhabdoid tumor 24 | 4,369
interstitial cystitis 24 | 2,299
lung adenocarcinoma 23 | 2,713
Cancer 22 | 2,346
pituitary cancer 22 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
oligodendroglioma 21 | 2,849
group 3 medulloblastoma 20 | 2,254
invasive ductal carcinoma 20 | 2,950
Breast cancer 19 | 3,094
pancreatic cancer 19 | 2,300
pilocytic astrocytoma 19 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
ulcerative colitis 17 | 2,087
ependymoma 16 | 2,514
malignant mesothelioma 16 | 3,162
spina bifida 15 | 1,064
adrenocortical carcinoma 14 | 1,427
adult high grade glioma 14 | 2,148
pediatric high grade glioma 14 | 2,712
primitive neuroectodermal tumor 14 | 3,031
subependymal giant cell astrocytoma 14 | 2,287
posterior fossa group B ependymoma 13 | 1,530
primary pancreatic ductal adenocarcinoma 13 | 1,271
astrocytic glioma 12 | 2,241
colon cancer 12 | 1,475
tuberculosis 12 | 1,557
Rheumatoid Arthritis 11 | 1,160
cystic fibrosis 11 | 1,665
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
Carcinoma 10 | 2,147
breast carcinoma 10 | 1,614
diabetes mellitus 10 | 1,663
ductal carcinoma in situ 10 | 1,745
Pick disease 9 | 1,893
atypical teratoid/rhabdoid tumor 9 | 1,095
cutaneous lupus erythematosus 9 | 1,056
group 4 medulloblastoma 9 | 1,875
sonic hedgehog group medulloblastoma 9 | 1,482
Atopic dermatitis 8 | 944
astrocytoma 8 | 1,493
medulloblastoma 8 | 1,524
non primary Sjogren syndrome sicca 8 | 840
posterior fossa group A ependymoma 8 | 1,511
Alzheimer's disease 7 | 644
gastric carcinoma 7 | 832
juvenile dermatomyositis 7 | 1,189
Obesity 6 | 616
Prostatic Neoplasms 6 | 471
mucosa-associated lymphoid tissue lymphoma 6 | 480
Duchenne muscular dystrophy 5 | 602
IGA Glomerulonephritis 5 | 454
Multiple Sclerosis 5 | 498
Multiple myeloma 5 | 1,327
active Crohn's disease 5 | 918
acute quadriplegic myopathy 5 | 1,157
hepatocellular carcinoma 5 | 532
nasopharyngeal carcinoma 5 | 1,056
primary Sjogren syndrome 5 | 789
Atherosclerosis 4 | 275
Cerebrovascular disease 4 | 231
Colorectal Neoplasms 4 | 217
Coronary artery disease 4 | 240
Dermatitis, Allergic Contact 4 | 66
Epilepsy 4 | 346
Intellectual disability 4 | 573
Mammary Neoplasms 4 | 410
Neurodegenerative disease 4 | 383
Peripheral Neuropathy 4 | 303
Polycystic Ovary Syndrome 4 | 332
Retinitis pigmentosa 4 | 153
Type 1 diabetes mellitus 4 | 101
acute myeloid leukemia 4 | 780
aldosterone-producing adenoma 4 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
chronic lymphosyte leukemia 4 | 232
chronic rhinosinusitis 4 | 512
fibroadenoma 4 | 557
glioblastoma multiforme 4 | 347
non-small cell lung carcinoma 4 | 413
Down syndrome 3 | 548
Endometriosis 3 | 535
Reperfusion Injury 3 | 84
Schizophrenia 3 | 501
Vascular disease 3 | 281
esophageal adenocarcinoma 3 | 737
head and neck cancer 3 | 270
nephrosclerosis 3 | 329
non diabetic and post-ischemic heart failure 3 | 200
pancreatic carcinoma 3 | 567
tuberculosis and treatment for 6 months 3 | 686

Tissue

Digestive Tract 110 | 18,473
Endocrine System 110 | 18,512
Female tissues 110 | 18,647
Nervous System 110 | 18,561
Blood and immune system 109 | 17,995
Liver and Pancreas 109 | 18,136
Male tissues 109 | 17,969
Skin and soft tissues 109 | 18,115
Urinary Tract 109 | 18,444
Cardiovascular System 108 | 17,958
Respiratory system 108 | 17,484

Target Family

Non-IDG 66 | 11,971
Enzyme 26 | 4,146
Transcription Factor 7 | 1,400
Kinase 4 | 634
GPCR 3 | 406
Ion Channel 3 | 341
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear cap-binding protein subunit 3 NCBP3 Tbio Non-IDG -1.68208 49.3 22
Lymphotoxin-alpha LTA Tbio Non-IDG -2.84770 612.8 461
Myb/SANT-like DNA-binding domain-containing protein 1 MSANTD1 Tdark Non-IDG 0.00000 22
Cytochrome b561 CYB561 Tbio Non-IDG -1.41910 20.4 45
Adipogenin ADIG Tdark Non-IDG -1.20658 16.0 3
Rho guanine nucleotide exchange factor 15 ARHGEF15 Tdark Non-IDG -0.67221 6.56 21
Ubiquitin-conjugating enzyme E2 B UBE2B Tbio Non-IDG -1.56439 38.8 140
Ras association domain-containing protein 8 RASSF8 Tbio Non-IDG -0.76280 7.37 201
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43357 2997.4 1177
Psychosine receptor GPR65 Tbio GPCR -1.43622 31.9 163