Development Level

Tbio 130 | 11,445
Tdark 37 | 6,588
Tchem 32 | 1,598
Tclin 11 | 613

Collection

RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

enlarged heart 210 | 210
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 119 | 11,493
ovarian cancer 109 | 8,520
psoriasis 90 | 6,694
osteosarcoma 89 | 7,950
lung cancer 77 | 4,740
medulloblastoma, large-cell 74 | 6,241
glioblastoma 66 | 5,792
atypical teratoid / rhabdoid tumor 55 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,955
lung carcinoma 51 | 2,843
group 3 medulloblastoma 49 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 48 | 3,291
invasive ductal carcinoma 48 | 2,951
Breast cancer 47 | 3,578
adult high grade glioma 47 | 3,801
non-small cell lung cancer 46 | 2,890
ependymoma 44 | 4,679
Cancer 42 | 2,499
interstitial cystitis 40 | 2,312
lung adenocarcinoma 40 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,989
malignant mesothelioma 39 | 3,232
pituitary cancer 38 | 1,972
oligodendroglioma 35 | 2,850
pancreatic cancer 35 | 2,398
subependymal giant cell astrocytoma 33 | 2,287
ulcerative colitis 32 | 1,819
primitive neuroectodermal tumor 31 | 3,035
Astrocytoma, Pilocytic 30 | 3,081
Kidney cancer 29 | 2,613
ductal carcinoma in situ 27 | 1,745
Autosomal recessive predisposition 26 | 1,442
Pick disease 26 | 1,894
adrenocortical carcinoma 26 | 1,428
astrocytic glioma 26 | 2,597
colon cancer 26 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
tuberculosis 26 | 2,010
Rheumatoid arthritis 24 | 1,191
breast carcinoma 23 | 1,638
cystic fibrosis 23 | 1,696
group 4 medulloblastoma 23 | 1,855
diabetes mellitus 22 | 1,728
cutaneous lupus erythematosus 20 | 1,057
spina bifida 20 | 1,074
Schizophrenia 18 | 1,160
primary pancreatic ductal adenocarcinoma 18 | 1,109
acute quadriplegic myopathy 16 | 1,158
active Crohn's disease 15 | 922
Atopic dermatitis 14 | 952
juvenile dermatomyositis 14 | 1,187
primary Sjogren syndrome 14 | 735
Epilepsy 13 | 792
Liver Cirrhosis, Experimental 13 | 769
Obesity 13 | 678
gastric carcinoma 13 | 807
non primary Sjogren syndrome sicca 13 | 891
astrocytoma 12 | 1,146
Endometriosis 11 | 540
Melanoma 11 | 711
Multiple Sclerosis 11 | 540
Seizures 11 | 596
posterior fossa group A ependymoma 11 | 468
Asthma 10 | 385
Bipolar Disorder 10 | 666
Depressive disorder 10 | 409
Intellectual disability 10 | 1,016
Neurodegenerative disease 10 | 414
medulloblastoma 10 | 720
nasopharyngeal carcinoma 10 | 1,058
posterior fossa group B ependymoma 10 | 416
Multiple myeloma 9 | 1,332
Prostatic Neoplasms 9 | 495
active ulcerative colitis 9 | 764
atypical teratoid/rhabdoid tumor 9 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
Muscle hypotonia 8 | 571
Nystagmus 8 | 317
hepatocellular carcinoma 8 | 547
pancreatic carcinoma 8 | 562
Alzheimer's disease 7 | 658
Hypertension 7 | 396
Kidney disease 7 | 430
Liver cancer 7 | 604
Lung Neoplasms 7 | 232
Retinitis Pigmentosa 7 | 226
acute myeloid leukemia 7 | 783
aldosterone-producing adenoma 7 | 665
esophageal adenocarcinoma 7 | 737
fibroadenoma 7 | 559
mucosa-associated lymphoid tissue lymphoma 7 | 484
urothelial carcinoma 7 | 318
Broad flat nasal bridge 6 | 236
Duchenne muscular dystrophy 6 | 601
Nasal bridge wide 6 | 236
Type 2 diabetes mellitus 6 | 272
chronic rhinosinusitis 6 | 512
nephrosclerosis 6 | 333
periodontitis 6 | 293
sonic hedgehog group medulloblastoma 6 | 467

Tissue

Endocrine System 206 | 18,159
Digestive Tract 203 | 17,369
Female tissues 202 | 17,400
Male tissues 201 | 17,142
Urinary Tract 200 | 16,678
Skin and soft tissues 199 | 17,230
Blood and immune system 198 | 16,909
Liver and Pancreas 196 | 16,750
Respiratory system 195 | 16,393
Nervous System 193 | 16,725
Cardiovascular System 176 | 15,192

Target Family

Non-IDG 113 | 12,091
Enzyme 51 | 4,145
Transcription Factor 16 | 1,400
GPCR 11 | 408
Kinase 8 | 634
Ion Channel 6 | 344
Transporter 3 | 473
Nuclear Receptor 2 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Transmembrane protein 160 TMEM160 Tdark Non-IDG 0.38 0.37 10
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Poly(A) RNA polymerase, mitochondrial MTPAP Tbio Enzyme -1.36829 24.0 68
Nucleoside diphosphate-linked moiety X motif 19 NUDT19 Tdark Non-IDG 0.90 0.09 79
POU domain, class 2, transcription factor 3 POU2F3 Tbio Transcription Factor -2.50813 322.4 96
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Cysteine-rich hydrophobic domain-containing protein 2 CHIC2 Tbio Non-IDG -2.12710 132.1 97
SID1 transmembrane family member 1 SIDT1 Tbio Non-IDG -1.59973 38.5 125
Gastrokine-2 GKN2 Tbio Non-IDG -2.35485 155.7 66