Development Level

Tbio 22 | 11,445
Tchem 4 | 1,598
Tdark 4 | 6,588
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

enlarged epididymis 31 | 31
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 18 | 11,493
ovarian cancer 16 | 8,520
psoriasis 16 | 6,694
glioblastoma 14 | 5,792
osteosarcoma 14 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
medulloblastoma, large-cell 13 | 6,241
ependymoma 11 | 4,679
atypical teratoid / rhabdoid tumor 10 | 5,112
Astrocytoma, Pilocytic 9 | 3,081
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
oligodendroglioma 9 | 2,850
adult high grade glioma 8 | 3,801
lung cancer 8 | 4,740
lung carcinoma 8 | 2,843
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
ulcerative colitis 7 | 1,819
Breast cancer 6 | 3,578
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pancreatic cancer 6 | 2,398
Pick disease 5 | 1,894
interstitial cystitis 5 | 2,312
malignant mesothelioma 5 | 3,232
tuberculosis 5 | 2,010
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
acute quadriplegic myopathy 4 | 1,158
pancreatic carcinoma 4 | 562
spina bifida 4 | 1,074
Alzheimer's disease 3 | 658
Barrett's esophagus 3 | 182
Cancer 3 | 2,499
Obesity 3 | 678
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
Acquired metabolic disease 2 | 336
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Bladder Neoplasm 2 | 112
Carcinoma, Transitional Cell 2 | 32
Crohn's disease 2 | 321
Endometriosis 2 | 540
Epilepsy 2 | 792
Gaucher disease type 1 2 | 180
Hypertension 2 | 396
Hypertensive disease 2 | 292
Hypomyelinating leukodystrophy 2 | 9
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Lung Neoplasms 2 | 232
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Neurodegenerative disease 2 | 414
Peripheral Neuropathy 2 | 134
Prostatic Neoplasms 2 | 495
Reperfusion Injury 2 | 86
Urinary Bladder Neoplasms 2 | 114
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
invasive ductal carcinoma 2 | 2,951
medulloblastoma 2 | 720
non diabetic and post-ischemic heart failure 2 | 200
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis and treatment for 6 months 2 | 409
type II diabetes mellitus and post-ischemic heart failure 2 | 88
Ataxia telangiectasia 1 | 34
Autosomal dominant nonsyndromic deafness 25 1 | 6
Birk-Barel syndrome 1 | 8
CNS hypomyelination 1 | 17
Charcot-Marie-Tooth disease axonal type 2K 1 | 2
Charcot-Marie-Tooth disease, Type 2K 1 | 2
Hepatitis, Chronic 1 | 23
Hyperthyroidism 1 | 53
Hypomyelination 1 | 17
Insulinoma 1 | 24
Latent syphilis 1 | 3
Polyneuropathy 1 | 64
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Takayasu's arteritis 1 | 53

Tissue

Endocrine System 30 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Urinary Tract 28 | 16,678
Digestive Tract 27 | 17,369
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Respiratory system 26 | 16,393
Cardiovascular System 25 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 6 | 4,145
Kinase 3 | 634
GPCR 2 | 408
Ion Channel 2 | 344
Transporter 2 | 473
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Transmembrane protein 174 TMEM174 Tdark Non-IDG -0.39794 2.90 25
Transmembrane protein 106B TMEM106B Tbio Non-IDG -1.54017 36.2 87
Sodium-dependent lysophosphatidylcholine symporter 1 MFSD2A Tbio Non-IDG -1.40175 26.3 73
Testis development-related protein TDRP Tbio Non-IDG -0.59437 4.93 39
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.34432 217.2 267
Fibronectin type III domain-containing protein 3B FNDC3B Tbio Non-IDG -1.38127 25.0 103
Psychosine receptor GPR65 Tbio GPCR -1.53268 38.5 173
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 Tchem Transporter -1.42715 25.8 76
Plasma membrane calcium-transporting ATPase 1 ATP2B1 Tbio Transporter -2.01694 100.0 110