Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

enlarged cecum 5 | 5
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 4 | 11,493
glioblastoma 4 | 5,792
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
atypical teratoid / rhabdoid tumor 3 | 5,112
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Melanoma 2 | 711
Pancreatitis 2 | 123
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
pediatric high grade glioma 2 | 1,064
Abdominal Pain 1 | 98
Abnormal blistering of the skin 1 | 54
Acne 1 | 52
Acquired metabolic disease 1 | 336
Acute coronary syndrome 1 | 39
Acute cystitis 1 | 35
Adenocarcinoma Of Esophagus 1 | 14
Age related macular degeneration 1 | 72
Aphthous stomatitis 1 | 16
Arthralgia 1 | 90
Aspergillosis 1 | 26
Behcet Syndrome 1 | 21
Behcet's syndrome 1 | 50
Blister of skin 1 | 54
Brain Injuries 1 | 65
Brain disease 1 | 96
Bronchiolitis 1 | 18
Calcium pyrophosphate deposition disease 1 | 13
Cataract 3 multiple types 1 | 10
Cholestasis, Extrahepatic 1 | 25
Colorectal Neoplasms 1 | 243
Common cold 1 | 67
Confusion 1 | 21
Corneal disease 1 | 31
Crohn Disease 1 | 45
Diabetic Neuropathies 1 | 14
Endometritis 1 | 21
Eosinophilia 1 | 28
Fatigue 1 | 182
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Fever 1 | 138
Fibrosis 1 | 44
Gastritis 1 | 47
Gastrointestinal Hemorrhage 1 | 52
Gaucher disease type 3 1 | 67
Hearing Loss 1 | 17
Hemiparesis 1 | 34
Human immunodeficiency virus infectious disease 1 | 138
Hypercalcemia 1 | 59
Hyperglycemia 1 | 137
Hypocalciuria 1 | 4
Hypoparathyroidism 1 | 41
Inflammation 1 | 120
Influenza 1 | 142
Intermittent migraine headaches 1 | 68
Keratitis 1 | 62
Keratoconjunctivitis sicca 1 | 25
Leptospirosis 1 | 18
Lipoma 1 | 32
Liver disease 1 | 237
Lung Injury 1 | 20
Macular degeneration 1 | 65
Mastitis 1 | 48
Melioidosis 1 | 17
Meningitis 1 | 67
Migraine Disorders 1 | 76
Nausea and vomiting 1 | 97
Neoplasm Metastasis 1 | 168
Otitis Media 1 | 52
Ovarian Neoplasms 1 | 102
Papule 1 | 43
Perinatal necrotizing enterocolitis 1 | 21
Pertussis 1 | 20
Photodysphoria 1 | 121
Photophobia 1 | 121
Pneumonia 1 | 174
Primary hyperparathyroidism 1 | 5
Recurrent aphthous ulcer 1 | 14
Respiratory Failure 1 | 104
Respiratory Hypersensitivity 1 | 19
Salmonellosis 1 | 42
Sepsis 1 | 24
Skin bulla 1 | 54
Substance abuse 1 | 59
Systemic lupus erythematosus 1 | 194
Uveitis 1 | 103
Venous Thrombosis 1 | 47
Ventricular Dysfunction, Left 1 | 22
hearing impairment 1 | 199
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 5 | 12,091

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 248 TMEM248 Tdark Non-IDG 0.00000 47
Golgi-associated PDZ and coiled-coil motif-containing protein GOPC Tbio Non-IDG -1.72940 54.1 368
AP-2 complex subunit sigma AP2S1 Tbio Non-IDG -1.42073 25.5 108
Islet cell autoantigen 1 ICA1 Tbio Non-IDG -1.84265 72.4 186
Toll-like receptor 4 TLR4 Tchem Non-IDG -3.81927 6905.8 1289