Development Level

Tbio 124 | 10,625
Tchem 33 | 1,890
Tdark 25 | 7,003
Tclin 5 | 602

IMPC Phenotype

embryonic lethality prior to t... 187 | 187
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 129 | 8,491
osteosarcoma 99 | 7,933
medulloblastoma, large-cell 70 | 6,234
glioblastoma 66 | 5,572
psoriasis 56 | 6,685
lung cancer 54 | 4,473
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,289
atypical teratoid / rhabdoid tumor 52 | 4,369
Breast cancer 49 | 3,098
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,988
Cancer 38 | 2,346
group 3 medulloblastoma 37 | 2,254
non-small cell lung cancer 37 | 2,798
primitive neuroectodermal tumor 37 | 3,031
ependymoma 36 | 2,514
oligodendroglioma 35 | 2,849
lung adenocarcinoma 33 | 2,714
malignant mesothelioma 33 | 3,163
astrocytic glioma 31 | 2,241
pancreatic cancer 31 | 2,300
pediatric high grade glioma 31 | 2,712
Pick disease 30 | 1,893
Carcinoma 28 | 2,147
breast carcinoma 26 | 1,614
invasive ductal carcinoma 26 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,795
pilocytic astrocytoma 25 | 3,086
diabetes mellitus 23 | 1,663
lung carcinoma 22 | 2,844
ulcerative colitis 22 | 2,087
astrocytoma 21 | 1,493
colon cancer 21 | 1,475
Multiple myeloma 20 | 1,327
adrenocortical carcinoma 20 | 1,427
dermatomyositis 19 | 966
medulloblastoma 19 | 1,524
pituitary cancer 18 | 1,972
spina bifida 18 | 1,064
tuberculosis 18 | 1,563
acute myeloid leukemia 17 | 785
acute quadriplegic myopathy 17 | 1,157
interstitial cystitis 17 | 2,299
subependymal giant cell astrocytoma 17 | 2,287
group 4 medulloblastoma 16 | 1,875
juvenile dermatomyositis 16 | 1,189
sonic hedgehog group medulloblastoma 16 | 1,482
adult high grade glioma 15 | 2,148
ductal carcinoma in situ 15 | 1,745
primary pancreatic ductal adenocarcinoma 15 | 1,271
posterior fossa group B ependymoma 13 | 1,530
Alzheimer's disease 12 | 644
Waldenstrons macroglobulinemia 12 | 764
atypical teratoid/rhabdoid tumor 12 | 1,095
hepatocellular carcinoma 12 | 550
non primary Sjogren syndrome sicca 12 | 840
posterior fossa group A ependymoma 12 | 1,511
Intellectual disability 11 | 573
Obesity 11 | 616
Parkinson's disease 11 | 364
cutaneous lupus erythematosus 11 | 1,056
IGA Glomerulonephritis 10 | 454
Neurodegenerative disease 10 | 383
Rheumatoid Arthritis 10 | 1,170
tuberculosis and treatment for 6 months 10 | 686
Endometriosis 9 | 535
pancreatic carcinoma 9 | 567
Down syndrome 8 | 548
Heart disease 8 | 279
Schizophrenia 8 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
glioblastoma multiforme 8 | 347
hereditary spastic paraplegia 8 | 313
Atopic dermatitis 7 | 944
primary Sjogren syndrome 7 | 788
Acquired metabolic disease 6 | 267
Cerebrovascular disease 6 | 231
Duchenne muscular dystrophy 6 | 602
Gaucher disease type 1 6 | 171
Mammary Neoplasms 6 | 410
Microcephaly 6 | 149
Polycystic Ovary Syndrome 6 | 334
Vascular disease 6 | 281
chronic rhinosinusitis 6 | 512
esophageal adenocarcinoma 6 | 737
inflammatory breast cancer 6 | 404
mucosa-associated lymphoid tissue lymphoma 6 | 480
progressive supranuclear palsy 6 | 674
Amyotrophic Lateral Sclerosis 5 | 432
Colorectal Neoplasms 5 | 217
Coronary artery disease 5 | 240
Craniofacial Abnormalities 5 | 147
Glioma 5 | 66
Multiple Sclerosis 5 | 498
Myocardial Infarction 5 | 126
aldosterone-producing adenoma 5 | 664
cystic fibrosis 5 | 1,670
fibroadenoma 5 | 557
gastric carcinoma 5 | 832
nasopharyngeal carcinoma 5 | 1,056

Tissue

Female tissues 187 | 18,646
Blood and immune system 186 | 17,994
Cardiovascular System 186 | 17,957
Digestive Tract 186 | 18,472
Endocrine System 186 | 18,511
Liver and Pancreas 186 | 18,135
Male tissues 186 | 17,968
Nervous System 186 | 18,560
Respiratory system 186 | 17,483
Skin and soft tissues 186 | 18,114
Urinary Tract 186 | 18,443

Target Family

Non-IDG 89 | 11,969
Enzyme 60 | 4,146
Transcription Factor 14 | 1,400
Kinase 10 | 634
Transporter 4 | 473
Epigenetic 3 | 242
Ion Channel 3 | 341
Nuclear Receptor 2 | 48
GPCR 1 | 408
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.85874 681.4 264
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
AT-rich interactive domain-containing protein 3A ARID3A Tbio Transcription Factor -2.07434 111.0 153
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.49911 286.4 377
Partner and localizer of BRCA2 PALB2 Tbio Non-IDG -2.10504 149.3 120
DnaJ homolog subfamily C member 9 DNAJC9 Tbio Non-IDG -0.73182 5.58 82
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.14104 13.5 159
A-kinase anchor protein 10, mitochondrial AKAP10 Tbio Enzyme -1.41278 26.4 193
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.22534 1564.7 495
Prolyl endopeptidase PREP Tchem Enzyme -2.48589 335.2 140