Development Level

Tbio 91 | 10,625
Tchem 29 | 1,890
Tdark 23 | 7,003
Tclin 5 | 602

IMPC Term

embryonic lethality prior to o... 148 | 148
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 93 | 8,484
osteosarcoma 77 | 7,933
medulloblastoma, large-cell 48 | 6,234
glioblastoma 46 | 5,572
lung cancer 43 | 4,466
psoriasis 43 | 6,685
atypical teratoid / rhabdoid tumor 31 | 4,369
Breast cancer 29 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
Cancer 27 | 2,346
primitive neuroectodermal tumor 27 | 3,031
group 3 medulloblastoma 26 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
malignant mesothelioma 25 | 3,162
Multiple myeloma 23 | 1,327
Carcinoma 22 | 2,147
diabetes mellitus 22 | 1,663
non-small cell lung cancer 21 | 2,798
pediatric high grade glioma 21 | 2,712
ependymoma 20 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,988
lung adenocarcinoma 20 | 2,713
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
Pick disease 19 | 1,893
astrocytic glioma 19 | 2,241
oligodendroglioma 18 | 2,849
astrocytoma 17 | 1,493
breast carcinoma 17 | 1,614
pancreatic cancer 17 | 2,300
invasive ductal carcinoma 15 | 2,950
acute myeloid leukemia 14 | 780
medulloblastoma 14 | 1,524
tuberculosis 14 | 1,557
colon cancer 13 | 1,475
dermatomyositis 13 | 933
pilocytic astrocytoma 13 | 3,086
Waldenstrons macroglobulinemia 12 | 765
adrenocortical carcinoma 12 | 1,427
non primary Sjogren syndrome sicca 11 | 840
pituitary cancer 11 | 1,972
posterior fossa group A ependymoma 11 | 1,511
sonic hedgehog group medulloblastoma 11 | 1,482
ulcerative colitis 11 | 2,087
Rheumatoid Arthritis 10 | 1,160
acute quadriplegic myopathy 10 | 1,157
adult high grade glioma 10 | 2,148
atypical teratoid/rhabdoid tumor 10 | 1,095
interstitial cystitis 10 | 2,299
Intellectual disability 9 | 573
juvenile dermatomyositis 9 | 1,189
spina bifida 9 | 1,064
subependymal giant cell astrocytoma 9 | 2,287
Neurodegenerative disease 8 | 383
ductal carcinoma in situ 8 | 1,745
hepatocellular carcinoma 8 | 532
lung carcinoma 8 | 2,844
Cerebrovascular disease 7 | 231
IGA Glomerulonephritis 7 | 454
Parkinson's disease 7 | 364
cutaneous lupus erythematosus 7 | 1,056
posterior fossa group B ependymoma 7 | 1,530
primary pancreatic ductal adenocarcinoma 7 | 1,271
progressive supranuclear palsy 7 | 674
Alzheimer's disease 6 | 644
Endometriosis 6 | 535
Epilepsy 6 | 346
Obesity 6 | 616
Polycystic Ovary Syndrome 6 | 332
hereditary spastic paraplegia 6 | 313
tuberculosis and treatment for 6 months 6 | 686
Leigh disease 5 | 81
Schizophrenia 5 | 501
group 4 medulloblastoma 5 | 1,875
pancreatic carcinoma 5 | 567
Amyotrophic Lateral Sclerosis 4 | 431
Atopic dermatitis 4 | 944
Colorectal Neoplasms 4 | 217
Gaucher disease type 1 4 | 171
Kidney disease 4 | 396
Malaria 4 | 140
Myocardial Infarction 4 | 126
Neuropathy 4 | 210
Pontocerebellar hypoplasia 4 | 29
Tetanus 4 | 66
chronic rhinosinusitis 4 | 512
esophageal adenocarcinoma 4 | 737
glioblastoma multiforme 4 | 347
inflammatory breast cancer 4 | 404
interstitial lung disease 4 | 291
nasopharyngeal carcinoma 4 | 1,056
primary Sjogren syndrome 4 | 789
Cockayne syndrome 3 | 54
Down syndrome 3 | 548
Liver carcinoma 3 | 217
Microcephaly 3 | 149
Multiple Sclerosis 3 | 498
Multiple acyl-CoA dehydrogenase deficiency 3 | 26
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
gastric carcinoma 3 | 832

Tissue

Blood and immune system 148 | 17,995
Cardiovascular System 148 | 17,958
Digestive Tract 148 | 18,473
Endocrine System 148 | 18,512
Female tissues 148 | 18,647
Liver and Pancreas 148 | 18,136
Male tissues 148 | 17,969
Nervous System 148 | 18,561
Respiratory system 148 | 17,484
Skin and soft tissues 148 | 18,115
Urinary Tract 148 | 18,444

Target Family

Enzyme 68 | 4,146
Non-IDG 64 | 11,971
Kinase 9 | 634
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Spermatogenesis-associated protein 5 SPATA5 Tchem Enzyme -2.14514 137.7 23
Prolyl endopeptidase PREP Tchem Enzyme -2.51026 335.2 140
Signal recognition particle 9 kDa protein SRP9 Tbio Non-IDG -1.49375 30.2 29
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.36455 23.7 59
Replication factor C subunit 1 RFC1 Tbio Non-IDG -1.40675 26.5 184
Cytochrome c oxidase assembly protein COX19 COX19 Tdark Enzyme -0.94445 8.14 35
39S ribosomal protein L51, mitochondrial MRPL51 Tdark Non-IDG -0.21560 1.59 76
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 Tclin Enzyme -2.85403 720.1 90
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600