Development Level

Tbio 25 | 10,625
Tdark 5 | 7,003
Tchem 2 | 1,890

IMPC Term

decreased threshold for audito... 32 | 32
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 17 | 7,933
psoriasis 16 | 6,685
ovarian cancer 15 | 8,484
glioblastoma 13 | 5,572
medulloblastoma, large-cell 12 | 6,234
atypical teratoid / rhabdoid tumor 11 | 4,369
group 3 medulloblastoma 9 | 2,254
lung carcinoma 9 | 2,844
pediatric high grade glioma 9 | 2,712
non-small cell lung cancer 8 | 2,798
ulcerative colitis 8 | 2,087
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
invasive ductal carcinoma 7 | 2,950
lung adenocarcinoma 7 | 2,713
Breast cancer 6 | 3,094
interstitial cystitis 6 | 2,299
primitive neuroectodermal tumor 6 | 3,031
Obesity 5 | 616
diabetes mellitus 5 | 1,663
lung cancer 5 | 4,466
pancreatic cancer 5 | 2,300
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
Pick disease 4 | 1,893
colon cancer 4 | 1,475
cystic fibrosis 4 | 1,665
ependymoma 4 | 2,514
gastric carcinoma 4 | 832
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
juvenile dermatomyositis 4 | 1,189
malignant mesothelioma 4 | 3,162
pilocytic astrocytoma 4 | 3,086
Rheumatoid Arthritis 3 | 1,160
adrenocortical carcinoma 3 | 1,427
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
cutaneous lupus erythematosus 3 | 1,056
ductal carcinoma in situ 3 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
spina bifida 3 | 1,064
Acquired metabolic disease 2 | 267
Atopic dermatitis 2 | 944
Carcinoma 2 | 2,147
Duchenne muscular dystrophy 2 | 602
Exfoliation syndrome 2 | 8
Glaucoma 2 | 134
Hyperglycemia 2 | 120
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
dermatomyositis 2 | 933
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,875
nephrosclerosis 2 | 329
pituitary cancer 2 | 1,972
tuberculosis 2 | 1,557
type II diabetes mellitus and post-ischemic heart failure 2 | 89
Adenoma 1 | 165
Amblyopia 1 | 24
Anoxia 1 | 33
Bladder Neoplasm 1 | 109
Cardiovascular system disease 1 | 194
Cataract 1 | 104
Colorectal Neoplasms 1 | 217
Congenital myasthenic syndrome 1 | 28
Cutis laxa 1 | 28
Cystic lymphangioma 1 | 14
Dermatitis, Atopic 1 | 45
Distal arthrogryposis 1 | 45
Endometrial Neoplasms 1 | 50
Glycogen storage disease IV 1 | 6
Heart conduction disease 1 | 65
Infertility 1 | 163
Kidney disease 1 | 396
Major Depressive Disorder 1 | 106
Megalocornea 1 | 15
Mental depression 1 | 58
Multiple pterygium syndrome 1 | 17
Muscle Weakness 1 | 92
Myopathy 1 | 128
Neuropathy 1 | 210
Parkinson's disease 1 | 364
Pena-Shokeir syndrome type I 1 | 3
Ptosis 1 | 42
Steatorrhea 1 | 20
Warburg micro syndrome 1 | 19
Weill-Marchesani syndrome 1 | 14
active ulcerative colitis 1 | 477
cystic fibrosis and chronic rhinosinusitis 1 | 213
hereditary spastic paraplegia 1 | 313
limb girdle muscular dystrophy 2A 1 | 156
medulloblastoma 1 | 1,524
tuberculosis and treatment for 3 months 1 | 327
tuberculosis and treatment for 6 months 1 | 686

Tissue

Endocrine System 31 | 18,512
Female tissues 31 | 18,647
Nervous System 31 | 18,561
Urinary Tract 31 | 18,444
Blood and immune system 30 | 17,995
Cardiovascular System 30 | 17,958
Digestive Tract 30 | 18,473
Male tissues 30 | 17,969
Liver and Pancreas 29 | 18,136
Skin and soft tissues 29 | 18,115
Respiratory system 28 | 17,484

Target Family

Non-IDG 18 | 11,971
Enzyme 12 | 4,146
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytoskeleton-associated protein 4 CKAP4 Tbio Non-IDG -1.40375 25.5 174
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.09236 133.4 142
Putative glycosylation-dependent cell adhesion molecule 1 GLYCAM1 Tdark Non-IDG 0.00000 0
Testicular haploid expressed gene protein-like THEGL Tdark Non-IDG -0.30103 2.00 1
DnaJ homolog subfamily C member 28 DNAJC28 Tbio Non-IDG -1.08705 10.6 81
Nucleoredoxin NXN Tbio Non-IDG -2.49829 323.4 88
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.30956 203.0 132
Transcription factor Sp5 SP5 Tdark Transcription Factor 0.30 0.34 14
Ubiquitin-like domain-containing CTD phosphatase 1 UBLCP1 Tchem Enzyme -0.58358 4.02 113