Development Level

Tbio 19 | 11,178
Tdark 5 | 6,569
Tchem 1 | 1,885
Tclin 1 | 612

IMPC Phenotype

decreased threshold for audito... 26 | 26
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 19 | 11,192
ovarian cancer 14 | 8,297
glioblastoma 13 | 5,635
medulloblastoma, large-cell 13 | 6,086
osteosarcoma 12 | 7,766
adult high grade glioma 10 | 3,701
psoriasis 10 | 6,514
atypical teratoid / rhabdoid tumor 9 | 4,971
lung cancer 9 | 4,607
ependymoma 8 | 4,559
tuberculosis 8 | 1,963
Astrocytoma, Pilocytic 7 | 3,006
interstitial cystitis 7 | 2,237
lung adenocarcinoma 7 | 2,627
primitive neuroectodermal tumor 7 | 2,957
Breast cancer 6 | 3,469
Cancer 6 | 2,388
group 3 medulloblastoma 6 | 4,002
pituitary cancer 6 | 1,915
adrenocortical carcinoma 5 | 1,385
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,204
invasive ductal carcinoma 5 | 2,867
lung carcinoma 5 | 2,755
non-small cell lung cancer 5 | 2,799
ulcerative colitis 5 | 1,765
Obesity 4 | 655
astrocytic glioma 4 | 2,530
breast carcinoma 4 | 1,589
colon cancer 4 | 1,428
ductal carcinoma in situ 4 | 1,686
esophageal adenocarcinoma 4 | 696
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,872
pancreatic cancer 4 | 2,322
Atopic dermatitis 3 | 915
Kidney cancer 3 | 2,548
Liver Cirrhosis, Experimental 3 | 733
Lung Neoplasms 3 | 217
active Crohn's disease 3 | 882
cystic fibrosis 3 | 1,629
hepatocellular carcinoma 3 | 536
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,902
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,911
Acquired metabolic disease 2 | 329
Amyotrophic lateral sclerosis 2 | 437
Autosomal recessive predisposition 2 | 1,407
Barrett's esophagus 2 | 173
Chronic Lymphocytic Leukemia 2 | 254
Liver disease 2 | 227
Mental Depression 2 | 325
Pick disease 2 | 1,856
Rheumatoid arthritis 2 | 1,156
acute myeloid leukemia 2 | 760
chronic rhinosinusitis 2 | 505
cutaneous lupus erythematosus 2 | 1,016
diabetes mellitus 2 | 1,683
medulloblastoma 2 | 702
nasopharyngeal carcinoma 2 | 1,024
posterior fossa group A ependymoma 2 | 456
Abdominal Pain 1 | 95
Basal cell carcinoma 1 | 54
Carcinoma, Basal Cell 1 | 28
Cardiovascular system disease 1 | 240
Chest Pain 1 | 38
Coarse hair 1 | 31
Common variable immunodeficiency 1 | 97
Congenital deafness 1 | 180
Deafness 1 | 193
Diabetes mellitus type 2 1 | 69
Ecchymosis 1 | 64
Ehlers-Danlos syndrome 1 | 43
Esophageal Neoplasms 1 | 68
Fatty liver disease 1 | 102
Flat face 1 | 51
Generalized osteopenia 1 | 94
Hearing Loss, Partial 1 | 180
Hemolytic anemia 1 | 73
Hypotrophic malar bone 1 | 129
Hypoxia 1 | 33
Increased tendency to bruise 1 | 64
Kabuki syndrome 1 | 27
Liver neoplasms 1 | 126
Lymphoid leukemia 1 | 156
Macular degeneration 1 | 64
Malar flattening 1 | 129
Nail dysplasia 1 | 51
Nausea and vomiting 1 | 93
Nephroblastoma 1 | 50
Opioid abuse 1 | 5
Osteopenia 1 | 94
Pathological fracture 1 | 19
Pneumonia 1 | 169
Rough hair texture 1 | 31
Squamous cell carcinoma 1 | 125
Weight Gain 1 | 95
Wilms Tumor 1 | 28
fascioscapulohumeral muscular dystrophy 1 | 98
hearing impairment 1 | 194
inflammatory breast cancer 1 | 272
non-small cell lung carcinoma 1 | 302
uncontrolled asthma 1 | 56

Tissue

Digestive Tract 26 | 17,369
Male tissues 26 | 17,142
Urinary Tract 26 | 16,678
Blood and immune system 25 | 16,909
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 7 | 4,145
Transcription Factor 4 | 1,400
GPCR 1 | 408
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ecto-NOX disulfide-thiol exchanger 1 ENOX1 Tbio Non-IDG -0.98119 9.05 62
Sorting nexin-29 SNX29 Tdark Non-IDG -0.08517 1.05 101
Protein FAM53B FAM53B Tbio Non-IDG -1.70473 50.6 24
Paired box protein Pax-5 PAX5 Tbio Transcription Factor -2.76237 578.2 633
Serine/threonine-protein phosphatase 6 catalytic subunit PPP6C Tbio Enzyme -2.41091 208.5 230
Deleted in lung and esophageal cancer protein 1 DLEC1 Tbio Non-IDG -1.59957 42.3 156
Ras GTPase-activating-like protein IQGAP2 IQGAP2 Tbio Enzyme -1.40687 25.2 146
DnaJ homolog subfamily C member 17 DNAJC17 Tdark Non-IDG -0.24678 1.72 125
Dipeptidyl peptidase 4 DPP4 Tclin Enzyme -3.64553 4548.3 1169
Platelet-activating factor receptor PTAFR Tchem GPCR -2.02420 116.1 134