Development Level

Tbio 54 | 11,445
Tdark 11 | 6,588
Tchem 8 | 1,598
Tclin 2 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased startle reflex 75 | 75
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 58 | 11,493
medulloblastoma, large-cell 37 | 6,241
ovarian cancer 37 | 8,520
osteosarcoma 34 | 7,950
atypical teratoid / rhabdoid tumor 33 | 5,112
glioblastoma 32 | 5,792
psoriasis 31 | 6,694
group 3 medulloblastoma 28 | 4,104
ependymoma 26 | 4,679
lung cancer 26 | 4,740
adult high grade glioma 23 | 3,801
Astrocytoma, Pilocytic 21 | 3,081
invasive ductal carcinoma 21 | 2,951
Breast cancer 19 | 3,578
primitive neuroectodermal tumor 19 | 3,035
astrocytic glioma 18 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
malignant mesothelioma 17 | 3,232
oligodendroglioma 17 | 2,850
lung carcinoma 16 | 2,843
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
lung adenocarcinoma 15 | 2,716
non-small cell lung cancer 15 | 2,890
Autosomal recessive predisposition 14 | 1,442
Kidney cancer 14 | 2,613
Pick disease 14 | 1,894
ductal carcinoma in situ 14 | 1,745
subependymal giant cell astrocytoma 14 | 2,287
Schizophrenia 11 | 1,160
adrenocortical carcinoma 11 | 1,428
Intellectual disability 10 | 1,016
colon cancer 10 | 1,478
cystic fibrosis 10 | 1,696
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
group 4 medulloblastoma 9 | 1,855
pancreatic cancer 9 | 2,398
spina bifida 9 | 1,074
Atopic dermatitis 8 | 952
Epilepsy 8 | 792
astrocytoma 8 | 1,146
ulcerative colitis 8 | 1,819
Cancer 7 | 2,499
Obesity 7 | 678
pituitary cancer 7 | 1,972
Dull intelligence 6 | 645
Low intelligence 6 | 645
Melanoma 6 | 711
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Nonsyndromic deafness 6 | 142
Poor school performance 6 | 645
breast carcinoma 6 | 1,638
progressive supranuclear palsy 6 | 676
tuberculosis 6 | 2,010
Bipolar Disorder 5 | 666
Multiple myeloma 5 | 1,332
Seizures 5 | 596
active ulcerative colitis 5 | 764
acute myeloid leukemia 5 | 783
diabetes mellitus 5 | 1,728
fibroadenoma 5 | 559
pediatric high grade glioma 5 | 1,064
Alzheimer's disease 4 | 658
Down syndrome 4 | 499
Endometrial cancer 4 | 311
Endometriosis 4 | 540
Hypertensive disease 4 | 292
Liver cancer 4 | 604
Muscle hypotonia 4 | 571
Neurodegenerative disease 4 | 414
Prostatic Neoplasms 4 | 495
Skin cancer 4 | 469
Small head 4 | 374
active Crohn's disease 4 | 922
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,057
facioscapulohumeral dystrophy 4 | 288
hereditary spastic paraplegia 4 | 318
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung carcinoma 4 | 317
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
Depressive disorder 3 | 409
Hypoplastic mandible condyle 3 | 275
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Rheumatoid arthritis 3 | 1,191
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
dermatomyositis 3 | 966
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
periodontitis 3 | 293

Tissue

Endocrine System 74 | 18,159
Digestive Tract 73 | 17,369
Nervous System 73 | 16,725
Female tissues 72 | 17,400
Liver and Pancreas 72 | 16,750
Male tissues 72 | 17,142
Skin and soft tissues 72 | 17,230
Respiratory system 71 | 16,393
Blood and immune system 70 | 16,909
Urinary Tract 69 | 16,678
Cardiovascular System 68 | 15,192

Target Family

Non-IDG 49 | 12,091
Enzyme 13 | 4,145
GPCR 4 | 408
Kinase 4 | 634
Transcription Factor 3 | 1,400
Transporter 2 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.68100 45.7 44
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
F-box only protein 2 FBXO2 Tbio Non-IDG -1.36281 26.8 157
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Dual specificity tyrosine-phosphorylation-regulated kinase 1B DYRK1B Tchem Kinase -1.63295 52.7 289
Ephrin type-A receptor 5 EPHA5 Tchem Kinase -2.28294 191.7 407
Glutathione S-transferase C-terminal domain-containing protein GSTCD Tbio Enzyme -0.63267 3.65 59