Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased spleen weight 10 | 10
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Breast cancer 7 | 3,578
Carcinoma 6 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Cancer 5 | 2,499
invasive ductal carcinoma 5 | 2,951
medulloblastoma, large-cell 5 | 6,241
Pick disease 4 | 1,894
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
Astrocytoma, Pilocytic 3 | 3,081
Obesity 3 | 678
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Adenocarcinoma 2 | 122
Arthrogryposis 2 | 54
Autosomal recessive predisposition 2 | 1,442
Blepharoptosis 2 | 231
Byzanthine arch palate 2 | 194
Cleft Palate 2 | 271
Congenital myasthenic syndrome 2 | 25
Easy fatigability 2 | 18
Endometriosis 2 | 540
Feeding difficulties 2 | 127
Gaucher disease type 1 2 | 180
Gowers sign 2 | 24
Gowers sign present 2 | 24
Granulosa cell tumor 2 | 6
Hyperglycemia 2 | 137
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Long face 2 | 71
Multiple myeloma 2 | 1,332
Muscle hypotonia 2 | 571
Myasthenic Syndrome, Congenital, 4C, Associated With Acetylcholine Receptor Deficiency 2 | 5
Reduced fetal movement 2 | 51
Tires quickly 2 | 18
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
group 4 medulloblastoma 2 | 1,855
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
Aarskog syndrome 1 | 12
Absence of secondary sex characteristics 1 | 22
Achondroplasia 1 | 21
Adrenal Gland Neoplasms 1 | 11
Adult T-cell leukemia 1 | 5
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Basal cell nevi 1 | 23
Clostridium difficile colitis 1 | 12
Cocaine Dependence 1 | 51
Cystic nephroma 1 | 5
Decreased T cell activation 1 | 4
Decreased testosterone in males 1 | 28
Diabetic Neuropathies 1 | 14
Dyslipidemias 1 | 27
EMG: decrement at repetitive stimulation 1 | 4
Exocrine pancreatic insufficiency 1 | 32
Goiter 1 | 38
Gynecomastia 1 | 64
Hypertriglyceridemia result 1 | 37
Malocclusion 1 | 57
Muscle Cramp 1 | 55
Muscle atrophy, proximal 1 | 11
Myasthenias 1 | 8
Oligospermia 1 | 36
Ophthalmoparesis 1 | 11
Presbyopia 1 | 20
Primary hypogonadism 1 | 37
Respiratory insufficiency due to muscle weakness 1 | 37
Seminoma 1 | 15
Type 2 fiber atrophy 1 | 8
Weak cry 1 | 17
Wiskott-Aldrich syndrome 1 | 30

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Atlastin-2 ATL2 Tbio Non-IDG -1.20941 15.1 91
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
JmjC domain-containing protein 5 KDM8 Tbio Epigenetic -1.68201 49.6 209
PRKC apoptosis WT1 regulator protein PAWR Tbio Non-IDG -1.93678 105.8 292
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 GFPT1 Tchem Enzyme -2.79406 584.2 135
Endoribonuclease Dicer DICER1 Tbio Enzyme -3.34177 2054.3 327
Bardet-Biedl syndrome 5 protein BBS5 Tbio Non-IDG -1.11389 8.11 84
Fibroblast growth factor 9 FGF9 Tbio Non-IDG -2.30869 217.7 272