Development Level

Tbio 18 | 11,445
Tdark 4 | 6,588
Tchem 3 | 1,598

IMPC Phenotype

decreased mean platelet volume 25 | 25
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 15 | 11,493
ovarian cancer 14 | 8,520
osteosarcoma 13 | 7,950
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
adult high grade glioma 9 | 3,801
ependymoma 8 | 4,679
lung cancer 8 | 4,740
astrocytic glioma 7 | 2,597
primitive neuroectodermal tumor 7 | 3,035
Autosomal recessive predisposition 6 | 1,442
group 3 medulloblastoma 6 | 4,104
psoriasis 6 | 6,694
Breast cancer 5 | 3,578
Epilepsy 5 | 792
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
Seizures 5 | 596
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
oligodendroglioma 5 | 2,850
Multiple myeloma 4 | 1,332
colon cancer 4 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
juvenile dermatomyositis 4 | 1,187
pituitary cancer 4 | 1,972
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Muscle hypotonia 3 | 571
Pick disease 3 | 1,894
adrenocortical carcinoma 3 | 1,428
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group B ependymoma 3 | 416
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Bipolar Disorder 2 | 666
Cardiomegaly 2 | 116
Cerebellar Ataxia 2 | 304
Chemical and Drug Induced Liver Injury 2 | 195
Cognitive delay 2 | 608
Dementia 2 | 175
Depressive disorder 2 | 409
Diarrhea 2 | 253
Dull intelligence 2 | 645
Dysarthria 2 | 192
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Goiter 2 | 38
Heart Diseases 2 | 43
Heart failure 2 | 162
Huntington's disease 2 | 76
Hypothyroidism 2 | 122
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Major Depressive Disorder 2 | 301
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Myopathy 2 | 185
Nephroblastoma 2 | 51
Nerve Degeneration 2 | 121
Neurodegenerative disease 2 | 414
Neutropenia 2 | 72
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Status Epilepticus 2 | 98
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
invasive ductal carcinoma 2 | 2,951
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
Apraxia 1 | 26
Biliary cirrhosis 1 | 45
Enlarged vestibular aqueduct 1 | 10
Lateral sclerosis 1 | 15
Legionellosis 1 | 4
Liver Cirrhosis, Biliary 1 | 33
Mulibrey nanism 1 | 13
Polydipsia 1 | 15
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Retinitis pigmentosa Y-linked 1 | 9

Tissue

Digestive Tract 25 | 17,369
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Skin and soft tissues 25 | 17,230
Blood and immune system 24 | 16,909
Endocrine System 24 | 18,159
Urinary Tract 24 | 16,678
Male tissues 23 | 17,142
Respiratory system 23 | 16,393
Cardiovascular System 22 | 15,192
Nervous System 22 | 16,725

Target Family

Enzyme 10 | 4,145
Non-IDG 6 | 12,091
Transcription Factor 3 | 1,400
Kinase 2 | 634
Transporter 2 | 473
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Ubiquitin carboxyl-terminal hydrolase 40 USP40 Tbio Enzyme -0.38917 2.14 68
F-box only protein 36 FBXO36 Tdark Non-IDG 0.48 0.00000 91
E3 ubiquitin-protein ligase TRIM37 TRIM37 Tbio Enzyme -3.25892 1754.8 177
Ubiquitin carboxyl-terminal hydrolase 22 USP22 Tbio Enzyme -1.68483 57.9 220
Zinc finger protein ZFP69 ZFP69 Tdark Transcription Factor -0.28887 3.03 25
ATP-dependent Clp protease proteolytic subunit, mitochondrial CLPP Tbio Enzyme -2.67803 471.0 188
Canalicular multispecific organic anion transporter 1 ABCC2 Tchem Transporter -2.90204 834.9 234
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform PPP2R5E Tbio Enzyme -0.83365 5.54 91
Persulfide dioxygenase ETHE1, mitochondrial ETHE1 Tbio Enzyme -1.85699 73.4 147