Development Level

Tbio 58 | 11,445
Tchem 12 | 1,598
Tdark 5 | 6,588
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased mean corpuscular vol... 79 | 79
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 55 | 11,493
osteosarcoma 40 | 7,950
ovarian cancer 40 | 8,520
psoriasis 36 | 6,694
glioblastoma 35 | 5,792
atypical teratoid / rhabdoid tumor 31 | 5,112
medulloblastoma, large-cell 30 | 6,241
lung cancer 23 | 4,740
malignant mesothelioma 21 | 3,232
adult high grade glioma 20 | 3,801
ependymoma 20 | 4,679
group 3 medulloblastoma 20 | 4,104
Breast cancer 19 | 3,578
Cancer 19 | 2,499
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
non-small cell lung cancer 17 | 2,890
Autosomal recessive predisposition 15 | 1,442
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
pancreatic cancer 15 | 2,398
Kidney cancer 14 | 2,613
lung carcinoma 14 | 2,843
primitive neuroectodermal tumor 14 | 3,035
subependymal giant cell astrocytoma 14 | 2,287
astrocytic glioma 13 | 2,597
lung adenocarcinoma 13 | 2,716
Rheumatoid arthritis 12 | 1,191
adrenocortical carcinoma 11 | 1,428
breast carcinoma 11 | 1,638
invasive ductal carcinoma 11 | 2,951
juvenile dermatomyositis 11 | 1,187
tuberculosis 11 | 2,010
astrocytoma 10 | 1,146
cutaneous lupus erythematosus 10 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Pick disease 9 | 1,894
colon cancer 9 | 1,478
group 4 medulloblastoma 9 | 1,855
mucosa-associated lymphoid tissue lymphoma 9 | 484
oligodendroglioma 9 | 2,850
Schizophrenia 8 | 1,160
ductal carcinoma in situ 8 | 1,745
ulcerative colitis 8 | 1,819
Dysarthria 7 | 192
Epilepsy 7 | 792
Liver cancer 7 | 604
Neurodegenerative disease 7 | 414
dermatomyositis 7 | 966
esophageal adenocarcinoma 7 | 737
medulloblastoma 7 | 720
pituitary cancer 7 | 1,972
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Muscle hypotonia 6 | 571
active Crohn's disease 6 | 922
acute myeloid leukemia 6 | 783
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Anemia 5 | 365
Arthritis, Rheumatoid 5 | 174
Breast Neoplasms 5 | 445
Carcinoma, Hepatocellular 5 | 228
Chemical and Drug Induced Liver Injury 5 | 195
Cholestasis 5 | 155
Depressive disorder 5 | 409
Down syndrome 5 | 499
Endometriosis 5 | 540
Gaucher disease type 1 5 | 180
Hypertension 5 | 396
Liver carcinoma 5 | 240
Muscle Spasticity 5 | 195
Obesity 5 | 678
Seizures 5 | 596
Short stature 5 | 531
Thrombocytopenia 5 | 197
acute quadriplegic myopathy 5 | 1,158
gastric carcinoma 5 | 807
hereditary spastic paraplegia 5 | 318
pediatric high grade glioma 5 | 1,064
progressive supranuclear palsy 5 | 676
sarcoidosis 5 | 370
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Kidney disease 4 | 430
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Poor school performance 4 | 645
Vascular disease 4 | 319
active ulcerative colitis 4 | 764
aldosterone-producing adenoma 4 | 665
fibroadenoma 4 | 559
hepatocellular carcinoma 4 | 547
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735

Tissue

Endocrine System 77 | 18,159
Male tissues 77 | 17,142
Digestive Tract 76 | 17,369
Female tissues 76 | 17,400
Liver and Pancreas 76 | 16,750
Skin and soft tissues 76 | 17,230
Nervous System 74 | 16,725
Urinary Tract 74 | 16,678
Blood and immune system 72 | 16,909
Cardiovascular System 70 | 15,192
Respiratory system 70 | 16,393

Target Family

Non-IDG 37 | 12,091
Enzyme 22 | 4,145
Kinase 6 | 634
Epigenetic 4 | 242
Transporter 4 | 473
Nuclear Receptor 2 | 48
GPCR 1 | 408
Ion Channel 1 | 344
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caskin-1 CASKIN1 Tdark Non-IDG -0.63111 5.31 22
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
BAG family molecular chaperone regulator 1 BAG1 Tbio Non-IDG -2.50252 335.1 394
ER membrane protein complex subunit 10 EMC10 Tbio Non-IDG -1.41680 25.5 60
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Cytosolic 5'-nucleotidase 1B NT5C1B Tbio Enzyme -1.94015 85.4 93
Acyl-coenzyme A thioesterase 4 ACOT4 Tbio Enzyme -0.53787 2.87 58
F-box/WD repeat-containing protein 2 FBXW2 Tbio Non-IDG -2.09381 115.1 104
F-box only protein 36 FBXO36 Tdark Non-IDG 0.48 0.00000 91
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214