Development Level

Tbio 51 | 11,445
Tchem 11 | 1,598
Tdark 8 | 6,588
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased leukocyte cell numbe... 73 | 73
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 50 | 11,493
ovarian cancer 43 | 8,520
osteosarcoma 42 | 7,950
medulloblastoma, large-cell 31 | 6,241
psoriasis 31 | 6,694
glioblastoma 26 | 5,792
atypical teratoid / rhabdoid tumor 23 | 5,112
adult high grade glioma 19 | 3,801
ependymoma 19 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
group 3 medulloblastoma 18 | 4,104
lung cancer 18 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
Pick disease 16 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
Astrocytoma, Pilocytic 15 | 3,081
Breast cancer 15 | 3,578
Cancer 15 | 2,499
astrocytic glioma 15 | 2,597
invasive ductal carcinoma 15 | 2,951
malignant mesothelioma 15 | 3,232
interstitial cystitis 14 | 2,312
non-small cell lung cancer 14 | 2,890
Kidney cancer 13 | 2,613
lung adenocarcinoma 13 | 2,716
lung carcinoma 13 | 2,843
oligodendroglioma 13 | 2,850
juvenile dermatomyositis 12 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
diabetes mellitus 11 | 1,728
adrenocortical carcinoma 10 | 1,428
group 4 medulloblastoma 10 | 1,855
pancreatic cancer 10 | 2,398
primary Sjogren syndrome 10 | 735
breast carcinoma 9 | 1,638
cutaneous lupus erythematosus 9 | 1,057
ductal carcinoma in situ 9 | 1,745
primitive neuroectodermal tumor 9 | 3,035
progressive supranuclear palsy 9 | 676
subependymal giant cell astrocytoma 9 | 2,287
ulcerative colitis 9 | 1,819
pituitary cancer 8 | 1,972
Multiple myeloma 7 | 1,332
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
colon cancer 7 | 1,478
spina bifida 7 | 1,074
Autosomal recessive predisposition 6 | 1,442
Rheumatoid arthritis 6 | 1,191
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
cystic fibrosis 6 | 1,696
tuberculosis 6 | 2,010
tuberculosis and treatment for 6 months 6 | 409
Obesity 5 | 678
dermatomyositis 5 | 966
pediatric high grade glioma 5 | 1,064
Atopic dermatitis 4 | 952
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Immune system cancer 4 | 140
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Melanoma 4 | 711
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
Skin cancer 4 | 469
active Crohn's disease 4 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
gastric cancer 4 | 459
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
hereditary spastic paraplegia 4 | 318
pancreatic carcinoma 4 | 562
Acquired metabolic disease 3 | 336
Anemia 3 | 365
Attention deficit hyperactivity disorder 3 | 278
Broad flat nasal bridge 3 | 236
Conductive hearing loss 3 | 123
Down syndrome 3 | 499
Dull intelligence 3 | 645
Hyperinsulinism 3 | 133
Hypertensive disease 3 | 292
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Nasal bridge wide 3 | 236
Poor school performance 3 | 645
Precursor Cell Lymphoblastic Leukemia Lymphoma 3 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 | 49
Short stature 3 | 531
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
chronic rhinosinusitis 3 | 512
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333
periodontitis 3 | 293
posterior fossa group A ependymoma 3 | 468
sarcoidosis 3 | 370
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 73 | 18,159
Skin and soft tissues 73 | 17,230
Digestive Tract 72 | 17,369
Male tissues 72 | 17,142
Blood and immune system 71 | 16,909
Female tissues 71 | 17,400
Liver and Pancreas 71 | 16,750
Nervous System 70 | 16,725
Urinary Tract 70 | 16,678
Respiratory system 69 | 16,393
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 38 | 12,091
Enzyme 19 | 4,145
Kinase 6 | 634
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
GPCR 2 | 408
Transporter 2 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-citrylglutamate synthase B RIMKLB Tdark Enzyme -0.33579 2.63 48
A-kinase anchor protein 11 AKAP11 Tbio Enzyme -1.02415 11.7 38
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
Poly(ADP-ribose) glycohydrolase PARG Tchem Enzyme -2.32776 229.4 126
Dual specificity tyrosine-phosphorylation-regulated kinase 1B DYRK1B Tchem Kinase -1.63295 52.7 289
Phospholipase ABHD3 ABHD3 Tbio Enzyme -0.41218 2.23 91
Major facilitator superfamily domain-containing protein 10 MFSD10 Tbio Non-IDG -2.17526 146.3 66
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
Ubiquitin carboxyl-terminal hydrolase 40 USP40 Tbio Enzyme -0.38917 2.14 68
Selenoprotein W SELENOW Tbio Non-IDG -1.83127 70.7 63