Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased large unstained cell... 11 | 11
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 10 | 11,493
psoriasis 7 | 6,694
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
Cancer 4 | 2,499
diabetes mellitus 4 | 1,728
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
Kidney cancer 3 | 2,613
Multiple myeloma 3 | 1,332
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
Allergic hypersensitivity disease 2 | 126
Celiac disease 2 | 116
Chronic Lymphocytic Leukemia 2 | 262
Crohn's disease 2 | 321
Hypertensive disease 2 | 292
Intellectual disability 2 | 1,016
Kidney disease 2 | 430
Obesity 2 | 678
Pick disease 2 | 1,894
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid / rhabdoid tumor 2 | 5,112
cutaneous lupus erythematosus 2 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
ulcerative colitis 2 | 1,819
Abnormality of metabolism/homeostasis 1 | 134
Acute intermittent porphyria 1 | 15
Acute kidney injury 1 | 70
Acute myeloid leukemia, disease 1 | 30
Aggressive systemic mastocytosis 1 | 20
Alcohol dependence 1 | 107
Amnestic disorder 1 | 35
Angina Pectoris 1 | 32
Autistic Disorder 1 | 364
Barrett's esophagus 1 | 182
Brain disease 1 | 96
Cardiac Arrhythmia 1 | 103
Cardiomyopathies 1 | 110
Cocaine Dependence 1 | 51
Common variable immunodeficiency 1 | 101
Congestive heart failure 1 | 113
Dehydration 1 | 40
Depressed mood 1 | 17
Fatty liver disease 1 | 103
Fever 1 | 138
Generalized osteopenia 1 | 99
Glomerulonephritis 1 | 46
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
HIV Infections 1 | 102
Heart failure 1 | 162
Hyperaldosteronism 1 | 35
Hyperalgesia 1 | 83
Hypercalcemia 1 | 59
Hypertension, Portal 1 | 22
Hypokalemia 1 | 52
Hypomyelinating leukodystrophy 6 1 | 26
Hypotension 1 | 82
Inflammatory Bowel Diseases 1 | 35
Influenza 1 | 142
Ischemia 1 | 28
Kidney Failure, Chronic 1 | 46
Lethargy 1 | 77
Lipidoses 1 | 19
Lipoidosis 1 | 19
Lupus erythematosus 1 | 57
Lymphoproliferative syndrome 1 | 58
Mast cell leukemia 1 | 13
Meniere's disease 1 | 24
Meningitis 1 | 67
Obesity, Abdominal 1 | 24
Osteopenia 1 | 99
Ovarian Neoplasms 1 | 102
Pain 1 | 103
Polyuria 1 | 23
Poor growth 1 | 114
Portal hypertension 1 | 20
Serum cholesterol raised 1 | 22
Small Cell Lung Carcinoma 1 | 41
Small cell carcinoma of lung 1 | 45
Substance Withdrawal Syndrome 1 | 55
Very poor growth 1 | 114
Weight decreased 1 | 103
Wide nose 1 | 35
adult-onset Still's disease 1 | 8
chorea-acanthocytosis 1 | 12
facioscapulohumeral dystrophy 1 | 288
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 11 | 16,909
Endocrine System 11 | 18,159
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Respiratory system 10 | 16,393
Nervous System 9 | 16,725
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 5 | 12,091
Kinase 3 | 634
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-19 RAB19 Tdark Enzyme -0.54731 3.31 75
Dual specificity tyrosine-phosphorylation-regulated kinase 1B DYRK1B Tchem Kinase -1.63295 52.7 289
Integrin alpha-E ITGAE Tbio Non-IDG -2.61450 414.3 758
S phase cyclin A-associated protein in the endoplasmic reticulum SCAPER Tbio Enzyme -0.89697 7.86 42
Serine/threonine-protein kinase N1 PKN1 Tchem Kinase -2.03368 117.6 153
Zinc finger protein Aiolos IKZF3 Tbio Transcription Factor -1.82293 59.0 314
Syntaxin-7 STX7 Tbio Non-IDG -1.28658 20.5 108
Interleukin-18 receptor accessory protein IL18RAP Tbio Non-IDG -1.53093 27.6 249
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.92570 8381.2 203
Fatty acid-binding protein, liver FABP1 Tchem Non-IDG -2.57840 448.8 411