Development Level

Tbio 17 | 10,625
Tdark 6 | 7,003
Tchem 1 | 1,890
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

decreased hematocrit 25 | 25
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 14 | 7,933
ovarian cancer 14 | 8,484
medulloblastoma, large-cell 13 | 6,234
psoriasis 13 | 6,685
lung cancer 10 | 4,466
Cancer 9 | 2,346
glioblastoma 9 | 5,572
atypical teratoid / rhabdoid tumor 8 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
lung adenocarcinoma 8 | 2,713
Carcinoma 7 | 2,147
lung carcinoma 7 | 2,844
Pick disease 6 | 1,893
group 4 medulloblastoma 6 | 1,875
malignant mesothelioma 6 | 3,162
non-small cell lung cancer 6 | 2,798
pilocytic astrocytoma 6 | 3,086
Breast cancer 5 | 3,094
ductal carcinoma in situ 5 | 1,745
interstitial cystitis 5 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
invasive ductal carcinoma 5 | 2,950
progressive supranuclear palsy 5 | 674
adult high grade glioma 4 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
pancreatic cancer 4 | 2,300
pediatric high grade glioma 4 | 2,712
posterior fossa group A ependymoma 4 | 1,511
primitive neuroectodermal tumor 4 | 3,031
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 2,087
Obesity 3 | 616
Rheumatoid Arthritis 3 | 1,160
adrenocortical carcinoma 3 | 1,427
astrocytoma 3 | 1,493
breast carcinoma 3 | 1,614
colon cancer 3 | 1,475
cutaneous lupus erythematosus 3 | 1,056
ependymoma 3 | 2,514
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,189
nasopharyngeal carcinoma 3 | 1,056
primary Sjogren syndrome 3 | 789
tuberculosis and treatment for 6 months 3 | 686
Alzheimer's disease 2 | 644
Colonic Neoplasms 2 | 126
Gamma chain deficiency 2 | 7
IGA Glomerulonephritis 2 | 454
Intellectual disability 2 | 573
Leukemia 2 | 88
Lymphoid leukemia 2 | 69
MYELODYSPLASTIC SYNDROME 2 | 36
Melanoma 2 | 261
Neurodegenerative disease 2 | 383
Osteoporosis 2 | 257
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
cystic fibrosis 2 | 1,665
diabetes mellitus 2 | 1,663
gastric cancer 2 | 430
group 3 medulloblastoma 2 | 2,254
medulloblastoma 2 | 1,524
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
Anemia 1 | 252
Arthritis, Experimental 1 | 39
Ataxia 1 | 15
Autistic Disorder 1 | 320
Barrett's esophagus 1 | 183
Bipolar Disorder 1 | 266
Blood pressure finding 1 | 56
Chronic Lymphocytic Leukemia 1 | 242
Congenital Heart Defects 1 | 37
Corneal dystrophy 1 | 15
Diabetes Mellitus, Insulin-Dependent 1 | 76
Gaucher disease type 1 1 | 171
Hypercalcemia 1 | 37
Impotence 1 | 45
Intracranial aneurysm 1 | 20
Keratitis 1 | 42
Lennox-Gastaut syndrome 1 | 34
Liver Cirrhosis 1 | 101
Liver Cirrhosis, Experimental 1 | 108
Mammary Neoplasms 1 | 410
Myeloid Leukemia 1 | 19
Nasopharyngeal Neoplasms 1 | 8
Neoplasm Metastasis 1 | 138
Nerve Degeneration 1 | 73
Parkinson Disease 1 | 102
Posterior polymorphous corneal dystrophy 1 | 24
Retinal Degeneration 1 | 49
Sensorineural hearing loss 1 | 107
Systemic arterial pressure 1 | 56
facioscapulohumeral dystrophy 1 | 286
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
interstitial lung disease 1 | 291
ovarian neoplasm 1 | 97
pre-eclampsia 1 | 67
sarcoidosis 1 | 358

Tissue

Blood and immune system 24 | 17,995
Cardiovascular System 24 | 17,958
Digestive Tract 24 | 18,473
Endocrine System 24 | 18,512
Female tissues 24 | 18,647
Liver and Pancreas 24 | 18,136
Male tissues 24 | 17,969
Nervous System 24 | 18,561
Respiratory system 24 | 17,484
Skin and soft tissues 24 | 18,115
Urinary Tract 24 | 18,444

Target Family

Non-IDG 13 | 11,971
Enzyme 3 | 4,146
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Kinase 2 | 634
GPCR 1 | 406
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin-conjugating enzyme E2 variant 3 UEVLD Tdark Non-IDG 0.18 0.85 86
Pleckstrin homology domain-containing family M member 2 PLEKHM2 Tbio Non-IDG -0.22831 2.68 56
Adhesion G protein-coupled receptor F5 ADGRF5 Tbio GPCR -0.84160 8.64 151
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80612 564.2 147
StAR-related lipid transfer protein 13 STARD13 Tbio Non-IDG -2.01188 73.4 68
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -0.97785 9.77 84
5'-AMP-activated protein kinase subunit beta-1 PRKAB1 Tbio Kinase -1.43972 28.8 495
Dynactin subunit 5 DCTN5 Tdark Non-IDG 0.06 0.65 35
F-box only protein 7 FBXO7 Tbio Non-IDG -1.99755 105.5 78
Diphthine--ammonia ligase DPH6 Tdark Enzyme -0.39545 3.06 13