Development Level

Tbio 29 | 10,625
Tchem 6 | 1,890
Tdark 6 | 7,003
Tclin 3 | 602

IMPC Term

decreased heart weight 44 | 44
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 26 | 8,484
osteosarcoma 24 | 7,933
psoriasis 22 | 6,685
glioblastoma 21 | 5,572
medulloblastoma, large-cell 17 | 6,234
atypical teratoid / rhabdoid tumor 15 | 4,369
lung cancer 14 | 4,466
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
malignant mesothelioma 13 | 3,162
non-small cell lung cancer 13 | 2,798
Breast cancer 12 | 3,094
invasive ductal carcinoma 12 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
cystic fibrosis 10 | 1,665
oligodendroglioma 10 | 2,849
pilocytic astrocytoma 10 | 3,086
astrocytic glioma 9 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
breast carcinoma 8 | 1,614
colon cancer 8 | 1,475
pituitary cancer 8 | 1,972
acute quadriplegic myopathy 7 | 1,157
ductal carcinoma in situ 7 | 1,745
ependymoma 7 | 2,514
pediatric high grade glioma 7 | 2,712
primitive neuroectodermal tumor 7 | 3,031
Cancer 6 | 2,346
Carcinoma 6 | 2,147
Prostatic Neoplasms 6 | 471
adrenocortical carcinoma 6 | 1,427
adult high grade glioma 6 | 2,148
juvenile dermatomyositis 6 | 1,189
lung adenocarcinoma 6 | 2,713
lung carcinoma 6 | 2,844
medulloblastoma 6 | 1,524
spina bifida 6 | 1,064
ulcerative colitis 6 | 2,087
Atopic dermatitis 5 | 944
Neurodegenerative disease 5 | 383
astrocytoma 5 | 1,493
diabetes mellitus 5 | 1,663
esophageal adenocarcinoma 5 | 737
group 3 medulloblastoma 5 | 2,254
interstitial cystitis 5 | 2,299
pancreatic cancer 5 | 2,300
posterior fossa group A ependymoma 5 | 1,511
posterior fossa group B ependymoma 5 | 1,530
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 1,557
Duchenne muscular dystrophy 4 | 602
Multiple myeloma 4 | 1,327
Parkinson's disease 4 | 364
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
cutaneous lupus erythematosus 4 | 1,056
group 4 medulloblastoma 4 | 1,875
non primary Sjogren syndrome sicca 4 | 840
Amyotrophic Lateral Sclerosis 3 | 431
Intellectual disability 3 | 573
Obesity 3 | 616
Osteoporosis 3 | 257
Peripheral Neuropathy 3 | 303
aldosterone-producing adenoma 3 | 664
atypical teratoid/rhabdoid tumor 3 | 1,095
gastric carcinoma 3 | 832
hepatocellular carcinoma 3 | 532
limb girdle muscular dystrophy 2A 3 | 156
primary Sjogren syndrome 3 | 789
sonic hedgehog group medulloblastoma 3 | 1,482
Atherosclerosis 2 | 275
Colonic Neoplasms 2 | 126
Colorectal Neoplasms 2 | 217
Dementia 2 | 129
Down syndrome 2 | 548
Endometriosis 2 | 535
Gout 2 | 93
Hypertension 2 | 287
Hypophosphatemia 2 | 31
IGA Glomerulonephritis 2 | 454
Kidney disease 2 | 396
Liver carcinoma 2 | 217
Major Depressive Disorder 2 | 106
Multiple Sclerosis 2 | 498
Osteomalacia 2 | 28
Paraplegia 2 | 71
Pick disease 2 | 1,893
Rickets 2 | 42
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
acute myeloid leukemia 2 | 780
fibroadenoma 2 | 557
glioblastoma multiforme 2 | 347
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
hereditary spastic paraplegia 2 | 313
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
nephrosclerosis 2 | 329
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
progressive supranuclear palsy 2 | 674
tuberculosis and treatment for 6 months 2 | 686

Tissue

Digestive Tract 44 | 18,473
Endocrine System 44 | 18,512
Female tissues 44 | 18,647
Liver and Pancreas 44 | 18,136
Nervous System 44 | 18,561
Urinary Tract 44 | 18,444
Blood and immune system 43 | 17,995
Cardiovascular System 43 | 17,958
Male tissues 43 | 17,969
Respiratory system 43 | 17,484
Skin and soft tissues 43 | 18,115

Target Family

Non-IDG 21 | 11,971
Enzyme 15 | 4,146
GPCR 2 | 406
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 341
Kinase 1 | 634
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 24 USP24 Tbio Enzyme -1.53939 36.4 61
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.90528 8199.7 1129
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha PPP2R3A Tbio Enzyme -1.19072 14.4 144
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.65191 464.3 66
Perforin-1 PRF1 Tchem Non-IDG -3.16155 1480.8 325
F-box only protein 11 FBXO11 Tbio Non-IDG -1.42729 28.9 226
Proenkephalin-A PENK Tbio Non-IDG -3.06933 1145.9 230
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.52612 2.59 159
AP-4 complex subunit epsilon-1 AP4E1 Tdark Non-IDG -0.63202 4.65 21
Phosphate-regulating neutral endopeptidase PHEX Tbio Enzyme -3.21267 1694.4 98