Development Level

Tbio 9 | 11,445
Tdark 3 | 6,588
Tclin 1 | 613

IMPC Phenotype

decreased heart rate variabili... 13 | 13
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 10 | 11,493
glioblastoma 6 | 5,792
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
ovarian cancer 4 | 8,520
primitive neuroectodermal tumor 4 | 3,035
Alzheimer's disease 3 | 658
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
Atopic dermatitis 2 | 952
Epilepsy 2 | 792
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Multiple Sclerosis 2 | 540
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Alcohol dependence 1 | 107
Alcoholic Intoxication, Chronic 1 | 289
Amyotrophic lateral sclerosis 1 | 451
Amyotrophic lateral sclerosis type 3 1 | 17
Aortic aneurysm 1 | 38
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Autistic Disorder 1 | 364
Background diabetic retinopathy 1 | 3
Brain disease 1 | 96
Broad thumbs 1 | 28
Bulbous nasal tip 1 | 48
Bulbous nose 1 | 48
Cataract, Pulverulent 1 | 11
Choreatic disease 1 | 52
Ciliopathy 1 | 71
Cone dystrophy 1 | 71
Congenital Bilateral Cataracts 1 | 50
Congenital cataract 1 | 50
Diarrhea 1 | 253
Discordant ventriculoarterial connection 1 | 17
Disease Models, Animal 1 | 155
Dizziness 1 | 26
Eaton-Lambert syndrome 1 | 40
Enophthalmos 1 | 75
Fanconi anemia 1 | 56
Frontal bossing 1 | 157
Fundus dystrophy 1 | 83
Griscelli syndrome type 3 1 | 13
Hyperalgesia 1 | 83
Isolated cases 1 | 72
Isolated growth hormone deficiency type IA 1 | 1
Large intestine cancer 1 | 126
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Lymphoid leukemia 1 | 160
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 1 | 5
Meier-Gorlin syndrome 1 | 10
Microcephaly 1 | 166
Microphthalmia 1 | 76
Migraine Disorders 1 | 76
Myopia 1 | 176
Neoplasms, Germ Cell and Embryonal 1 | 15
Neuropathy 1 | 261
Nuclear cataract 1 | 19
Nuclear non-senile cataract 1 | 18
Parkinson Disease 1 | 64
Pneumonia 1 | 174
Pontocerebellar hypoplasia 1 | 36
Potato nose 1 | 48
Prion disease 1 | 16
Seckel syndrome 1 | 34
Sunken eyes 1 | 63
Toxic encephalopathy 1 | 141
Transient Cerebral Ischemia 1 | 25
Vertigo 1 | 29
Wilms Tumor 1 | 28
Xeroderma pigmentosum variant type 1 | 4
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
non-small cell lung carcinoma 1 | 317

Tissue

Endocrine System 13 | 18,159
Urinary Tract 13 | 16,678
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Skin and soft tissues 12 | 17,230
Liver and Pancreas 11 | 16,750
Respiratory system 10 | 16,393

Target Family

Non-IDG 10 | 12,091
Enzyme 2 | 4,145
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 3 KCNH3 Tclin Ion Channel -1.07866 11.8 67
Isthmin-2 ISM2 Tdark Non-IDG -1.39286 24.3 24
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Allograft inflammatory factor 1 AIF1 Tbio Non-IDG -3.07876 1105.3 601
DnaJ homolog subfamily C member 5G DNAJC5G Tdark Non-IDG 0.60 0.20 93
SH3-containing GRB2-like protein 3-interacting protein 1 SGIP1 Tbio Non-IDG -0.69901 5.35 72
ATR-interacting protein ATRIP Tbio Non-IDG -1.60828 43.0 359
V-set and immunoglobulin domain-containing protein 8 VSIG8 Tdark Non-IDG 0.00000 0
Prolow-density lipoprotein receptor-related protein 1 LRP1 Tbio Non-IDG -2.52012 357.1 711
Fatty acyl-CoA reductase 2 FAR2 Tbio Enzyme -1.12944 12.5 66