Development Level

Tbio 5 | 10,625
Tdark 1 | 7,003

IMPC Term

decreased food intake 6 | 6
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 6 | 8,492
medulloblastoma, large-cell 5 | 6,234
psoriasis 5 | 6,685
atypical teratoid / rhabdoid tumor 4 | 4,369
adult high grade glioma 3 | 2,148
glioblastoma 3 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung cancer 3 | 4,473
osteosarcoma 3 | 7,933
Breast cancer 2 | 3,099
Down syndrome 2 | 548
Obesity 2 | 616
cystic fibrosis 2 | 1,670
diabetes mellitus 2 | 1,663
group 4 medulloblastoma 2 | 1,875
interstitial cystitis 2 | 2,299
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,714
lung carcinoma 2 | 2,844
pancreatic cancer 2 | 2,300
pediatric high grade glioma 2 | 2,712
primary pancreatic ductal adenocarcinoma 2 | 1,271
primitive neuroectodermal tumor 2 | 3,031
AGAT deficiency 1 | 6
Acquired metabolic disease 1 | 267
Animal Mammary Neoplasms 1 | 136
Arginine:Glycine Amidinotransferase Deficiency 1 | 1
Atopic dermatitis 1 | 944
Cerebral creatine deficiency syndrome 3 1 | 1
Cervical cancer 1 | 23
Charcot-Marie-Tooth disease type 4 1 | 10
Cocaine dependence 1 | 24
Creatine transporter deficiency 1 | 4
Diarrhea 1 | 155
Duchenne muscular dystrophy 1 | 602
Endocrine System Diseases 1 | 2
Gas gangrene 1 | 15
Guanidinoacetate methyltransferase deficiency 1 | 4
Gyrate atrophy 1 | 8
Heart failure 1 | 80
Hepatitis 1 | 61
Hepatitis B 1 | 103
Insulin Resistance 1 | 50
Insulinoma 1 | 20
Intellectual disability 1 | 573
Juvenile arthritis 1 | 124
Kidney Diseases 1 | 86
Kidney disease 1 | 397
Liver Cirrhosis 1 | 101
Malignant fibroxanthoma 1 | 8
Mammary Neoplasms, Experimental 1 | 150
Mental depression 1 | 58
Myocardial Ischemia 1 | 169
Necrosis 1 | 51
X-linked cerebral adrenoleukodystrophy 1 | 115
active Crohn's disease 1 | 918
adrenocortical carcinoma 1 | 1,427
aldosterone-producing adenoma 1 | 664
astrocytic glioma 1 | 2,241
astrocytoma 1 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
breast carcinoma 1 | 1,614
chronic lymphocytic leukemia 1 | 244
cutaneous lupus erythematosus 1 | 1,056
ductal carcinoma in situ 1 | 1,745
fascioscapulohumeral muscular dystrophy 1 | 100
group 3 medulloblastoma 1 | 2,254
inflammatory breast cancer 1 | 404
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
juvenile dermatomyositis 1 | 1,189
malignant mesothelioma 1 | 3,163
medulloblastoma 1 | 1,524
mucosa-associated lymphoid tissue lymphoma 1 | 480
nephrosclerosis 1 | 329
non-small cell lung cancer 1 | 2,798
oligodendroglioma 1 | 2,849
pilocytic astrocytoma 1 | 3,086
posterior fossa group A ependymoma 1 | 1,511
sarcoidosis 1 | 368
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 3 months 1 | 327
type II diabetes mellitus and post-ischemic heart failure 1 | 89

Tissue

Blood and immune system 6 | 17,995
Cardiovascular System 6 | 17,958
Digestive Tract 6 | 18,473
Endocrine System 6 | 18,512
Female tissues 6 | 18,647
Liver and Pancreas 6 | 18,136
Male tissues 6 | 17,969
Nervous System 6 | 18,561
Respiratory system 6 | 17,484
Skin and soft tissues 6 | 18,115
Urinary Tract 6 | 18,444

Target Family

Enzyme 3 | 4,146
Non-IDG 3 | 11,969

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.33334 210.4 193
Carboxypeptidase E CPE Tbio Enzyme -2.99888 983.1 216
BTB/POZ domain-containing protein KCTD15 KCTD15 Tbio Non-IDG -1.00414 10.6 161
WD repeat and SOCS box-containing protein 2 WSB2 Tbio Non-IDG -1.06575 12.2 63
Cysteine-rich and transmembrane domain-containing protein 1 CYSTM1 Tdark Non-IDG 0.90 0.14 9
Ubiquitin-protein ligase E3C UBE3C Tbio Enzyme -1.08339 12.8 84