Development Level

Tbio 10 | 11,651
Tdark 3 | 6,593

IMPC Phenotype

decreased food intake 13 | 13
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 8 | 8,520
medulloblastoma, large-cell 7 | 6,241
Carcinoma 6 | 11,493
psoriasis 6 | 6,694
Breast cancer 5 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
lung cancer 5 | 4,740
osteosarcoma 5 | 7,950
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
Down syndrome 2 | 499
Kidney cancer 2 | 2,613
Liver Cirrhosis 2 | 181
Obesity 2 | 678
Pick disease 2 | 1,894
active Crohn's disease 2 | 922
breast carcinoma 2 | 1,638
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
Acquired metabolic disease 1 | 336
Alcoholic Intoxication, Chronic 1 | 289
Animal Mammary Neoplasms 1 | 136
Arthritis, Juvenile 1 | 126
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Cervical cancer 1 | 24
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 15
Cocaine Dependence 1 | 51
Delayed speech and language development 1 | 112
Diarrhea 1 | 253
Duchenne muscular dystrophy 1 | 601
Failure to gain weight 1 | 365
Gas gangrene 1 | 17
Goiter 1 | 38
Gyrate atrophy 1 | 7
Heart failure 1 | 162
Hepatitis B 1 | 108
Hypothyroidism 1 | 122
Infantile onset 1 | 238
Insulin Resistance 1 | 72
Isolated cleft palate 1 | 4
Juvenile arthritis 1 | 126
Kidney Diseases 1 | 114
Kidney disease 1 | 430
Language Delay 1 | 112
Liver Cirrhosis, Experimental 1 | 769
Lung Neoplasms 1 | 232
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mental Depression 1 | 333
Myocardial Ischemia 1 | 169
NEPHRONOPHTHISIS 2 1 | 5
Necrosis 1 | 53
Organic aciduria 1 | 6
Paget's disease of bone 1 | 36
Pediatric failure to thrive 1 | 365
Schizophrenia 1 | 1,160
Situs Inversus 1 | 65
Speech Delay 1 | 112
Speech impairment 1 | 112
X-linked cerebral adrenoleukodystrophy 1 | 116
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
fascioscapulohumeral muscular dystrophy 1 | 100
fibroadenoma 1 | 559
head and neck cancer 1 | 271
medulloblastoma 1 | 720
mucosa-associated lymphoid tissue lymphoma 1 | 484
nephrosclerosis 1 | 333
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
sarcoidosis 1 | 370
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010
type II diabetes mellitus and post-ischemic heart failure 1 | 88
uncontrolled asthma 1 | 56
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Nervous System 12 | 16,725
Respiratory system 12 | 16,393

Target Family

Non-IDG 7 | 12,091
Enzyme 6 | 4,145

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WD repeat and SOCS box-containing protein 2 WSB2 Tbio Non-IDG -1.13752 13.3 68
tRNA (uracil-5-)-methyltransferase homolog A TRMT2A Tdark Enzyme -0.48141 3.45 198
Dual oxidase maturation factor 2 DUOXA2 Tbio Enzyme -1.35199 19.7 84
Cysteine-rich and transmembrane domain-containing protein 1 CYSTM1 Tdark Non-IDG 0.90 0.14 12
MICOS complex subunit MIC26 APOO Tbio Non-IDG -1.25338 18.9 141
Structural maintenance of chromosomes protein 6 SMC6 Tbio Non-IDG -1.42371 20.0 115
Carboxypeptidase E CPE Tbio Enzyme -3.01460 1019.8 229
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.34742 219.1 219
BTB/POZ domain-containing protein KCTD15 KCTD15 Tbio Non-IDG -1.04860 11.7 176
Protein CASC4 CASC4 Tdark Non-IDG -0.73848 4.29 78