Development Level

Tbio 45 | 11,445
Tdark 9 | 6,588
Tchem 7 | 1,598
Tclin 4 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased fasted circulating g... 65 | 65
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 44 | 11,493
ovarian cancer 36 | 8,520
medulloblastoma, large-cell 34 | 6,241
glioblastoma 32 | 5,792
atypical teratoid / rhabdoid tumor 27 | 5,112
psoriasis 26 | 6,694
ependymoma 24 | 4,679
osteosarcoma 24 | 7,950
Breast cancer 21 | 3,578
adult high grade glioma 20 | 3,801
group 3 medulloblastoma 20 | 4,104
primitive neuroectodermal tumor 20 | 3,035
lung cancer 16 | 4,740
Astrocytoma, Pilocytic 14 | 3,081
Kidney cancer 14 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
invasive ductal carcinoma 14 | 2,951
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
lung carcinoma 12 | 2,843
oligodendroglioma 12 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Cancer 11 | 2,499
pituitary cancer 11 | 1,972
subependymal giant cell astrocytoma 11 | 2,287
Autosomal recessive predisposition 10 | 1,442
Pick disease 10 | 1,894
group 4 medulloblastoma 10 | 1,855
interstitial cystitis 10 | 2,312
malignant mesothelioma 10 | 3,232
ulcerative colitis 10 | 1,819
Epilepsy 9 | 792
colon cancer 9 | 1,478
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
non-small cell lung cancer 9 | 2,890
Intellectual disability 8 | 1,016
diabetes mellitus 8 | 1,728
lung adenocarcinoma 8 | 2,716
pancreatic cancer 8 | 2,398
Bipolar Disorder 7 | 666
Schizophrenia 7 | 1,160
spina bifida 7 | 1,074
tuberculosis 7 | 2,010
Endometriosis 6 | 540
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
fibroadenoma 6 | 559
Breast Neoplasms 5 | 445
Mammary Neoplasms 5 | 425
Neurodegenerative disease 5 | 414
Obesity 5 | 678
Vascular disease 5 | 319
acute quadriplegic myopathy 5 | 1,158
juvenile dermatomyositis 5 | 1,187
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
Alzheimer's disease 4 | 658
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Gait abnormality 4 | 135
Global developmental delay 4 | 608
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Neuropathy 4 | 261
Poor school performance 4 | 645
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
Small head 4 | 374
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
aldosterone-producing adenoma 4 | 665
cutaneous lupus erythematosus 4 | 1,057
gastric carcinoma 4 | 807
primary pancreatic ductal adenocarcinoma 4 | 1,109
Absent reflex 3 | 92
Absent tendon reflex 3 | 92
Autistic Disorder 3 | 364
Deafness 3 | 198
Decreased tendon reflex 3 | 122
Depressive disorder 3 | 409
Diarrhea 3 | 253
Failure to gain weight 3 | 365
Hepatomegaly 3 | 285
Hypoglycemia 3 | 152
Lung disease 3 | 142
Motor neuron disease 3 | 49
Multiple myeloma 3 | 1,332
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Reflex, Deep Tendon, Absent 3 | 92
Type 2 diabetes mellitus 3 | 272
acute myeloid leukemia 3 | 783
mucosa-associated lymphoid tissue lymphoma 3 | 484
progressive supranuclear palsy 3 | 676
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis and treatment for 6 months 3 | 409

Tissue

Endocrine System 64 | 18,159
Female tissues 63 | 17,400
Skin and soft tissues 63 | 17,230
Blood and immune system 62 | 16,909
Digestive Tract 62 | 17,369
Liver and Pancreas 62 | 16,750
Urinary Tract 62 | 16,678
Male tissues 61 | 17,142
Respiratory system 61 | 16,393
Nervous System 60 | 16,725
Cardiovascular System 59 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 12 | 4,145
Ion Channel 4 | 344
Kinase 4 | 634
Transcription Factor 3 | 1,400
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 1 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.68100 45.7 44
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
ER membrane protein complex subunit 10 EMC10 Tbio Non-IDG -1.41680 25.5 60
Oligoribonuclease, mitochondrial REXO2 Tbio Enzyme -2.15502 143.8 115
Histone-lysine N-methyltransferase NSD3 NSD3 Tbio Epigenetic -1.36629 23.0 234
Myelin protein P0 MPZ Tbio Non-IDG -2.55919 360.1 301
Tripartite motif-containing protein 55 TRIM55 Tdark Non-IDG -0.69631 4.68 132
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.29276 197.3 107