Development Level

Tbio 8 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased exploration in new e... 11 | 11
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 8 | 11,493
psoriasis 7 | 6,694
Breast cancer 5 | 3,578
lung carcinoma 5 | 2,843
Astrocytoma, Pilocytic 4 | 3,081
Melanoma 4 | 711
Schizophrenia 4 | 1,160
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
primitive neuroectodermal tumor 4 | 3,035
Endometrial cancer 3 | 311
Kidney cancer 3 | 2,613
Major Depressive Disorder 3 | 301
Prostatic Neoplasms 3 | 495
Unipolar Depression 3 | 250
lung adenocarcinoma 3 | 2,716
Alzheimer's disease 2 | 658
Bipolar Disorder 2 | 666
Chronic obstructive pulmonary disease 2 | 184
Coarse facial features 2 | 108
Depressive disorder 2 | 409
Intellectual disability 2 | 1,016
Macroglossia 2 | 65
Muscle hypotonia 2 | 571
Nephroblastoma 2 | 51
Parkinson's disease 2 | 392
Thickened facial skin with coarse facial features 2 | 108
Umbilical hernia 2 | 93
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
Abnormal helices 1 | 11
Accessory nipple 1 | 11
Acne vulgaris 1 | 14
Acute cystitis 1 | 35
Ampulla of Vater carcinoma 1 | 2
Amyloidosis 1 | 67
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Aortic aneurysm 1 | 38
Aplasia/Hypoplasia of the abdominal wall musculature 1 | 17
Autism Spectrum Disorders 1 | 75
Autoimmune thyroiditis 1 | 27
Broad feet 1 | 19
Bundle-Branch Block 1 | 8
CATARACT 16, MULTIPLE TYPES 1 | 15
Ciliopathy 1 | 71
Cloudy cornea 1 | 33
Common Migraine 1 | 7
Congenital diaphragmatic hernia 1 | 67
Congenital hypothyroidism 1 | 26
Corneal stromal opacities 1 | 33
Cystic kidney 1 | 30
Defect of vertebral segmentation 1 | 17
Dilatation of ureter 1 | 15
Discordant ventriculoarterial connection 1 | 17
Flared iliac wings 1 | 13
Fused vertebrae 1 | 25
Goiter 1 | 38
Graves' disease 1 | 24
Hypermobility syndrome 1 | 17
Malocclusion 1 | 57
Micronychia (disorder) 1 | 24
Microphthalmia 1 | 76
Migraine without Aura 1 | 11
Neoplasms 1 | 63
Pendred Syndrome 1 | 22
Polysplenia 1 | 7
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Prevention of Radiation-Induced Nausea and Vomiting 1 | 7
Pulmonary Stenosis 1 | 45
Renal cyst 1 | 30
Retinitis pigmentosa 28 1 | 19
Robinow syndrome 1 | 11
Short distal phalanges 1 | 50
Short hands 1 | 50
Spinal fusion 1 | 25
Syndactyly of fingers 1 | 48
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Uroureter 1 | 15
Vertebral body fusion 1 | 25
Williams Syndrome 1 | 10
Wilms Tumor 1 | 28
X- linked recessive 1 | 110
cone-rod dystrophy 1 | 59

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Male tissues 11 | 17,142
Skin and soft tissues 11 | 17,230
Liver and Pancreas 10 | 16,750
Respiratory system 10 | 16,393
Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Female tissues 9 | 17,400
Nervous System 9 | 16,725
Urinary Tract 9 | 16,678

Target Family

Non-IDG 7 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.68100 45.7 44
Protein FAM161A FAM161A Tbio Non-IDG -1.10138 14.2 50
Zinc finger MIZ domain-containing protein 2 ZMIZ2 Tdark Transcription Factor -0.58991 4.21 86
Myosin-1 MYH1 Tbio Non-IDG -1.94251 72.6 122
Pituitary homeobox 3 PITX3 Tbio Transcription Factor -2.26232 188.5 134
Estradiol 17-beta-dehydrogenase 1 HSD17B1 Tchem Enzyme -2.36315 220.8 198
Prolow-density lipoprotein receptor-related protein 1 LRP1 Tbio Non-IDG -2.52012 357.1 711
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Disks large homolog 4 DLG4 Tchem Non-IDG -2.98766 883.9 559
Glypican-4 GPC4 Tbio Non-IDG -1.59066 43.7 257