Development Level

Tbio 44 | 11,445
Tchem 9 | 1,598
Tdark 6 | 6,588
Tclin 3 | 613

IMPC Phenotype

decreased erythrocyte cell num... 62 | 62
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

osteosarcoma 38 | 7,950
Carcinoma 35 | 11,493
ovarian cancer 34 | 8,520
medulloblastoma, large-cell 24 | 6,241
psoriasis 24 | 6,694
atypical teratoid / rhabdoid tumor 22 | 5,112
lung cancer 22 | 4,740
ependymoma 21 | 4,679
glioblastoma 21 | 5,792
malignant mesothelioma 17 | 3,232
Astrocytoma, Pilocytic 15 | 3,081
Cancer 15 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
primitive neuroectodermal tumor 14 | 3,035
adult high grade glioma 12 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
non-small cell lung cancer 12 | 2,890
ulcerative colitis 12 | 1,819
Breast cancer 11 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
Autosomal recessive predisposition 10 | 1,442
Pick disease 10 | 1,894
group 3 medulloblastoma 10 | 4,104
lung adenocarcinoma 10 | 2,716
oligodendroglioma 10 | 2,850
subependymal giant cell astrocytoma 10 | 2,287
astrocytic glioma 9 | 2,597
group 4 medulloblastoma 9 | 1,855
interstitial cystitis 9 | 2,312
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
Kidney cancer 8 | 2,613
adrenocortical carcinoma 8 | 1,428
spina bifida 8 | 1,074
Schizophrenia 7 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pituitary cancer 7 | 1,972
Intellectual disability 6 | 1,016
Melanoma 6 | 711
Skin cancer 6 | 469
active Crohn's disease 6 | 922
acute myeloid leukemia 6 | 783
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
pancreatic cancer 6 | 2,398
progressive supranuclear palsy 6 | 676
tuberculosis 6 | 2,010
Bipolar Disorder 5 | 666
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
esophageal adenocarcinoma 5 | 737
juvenile dermatomyositis 5 | 1,187
non primary Sjogren syndrome sicca 5 | 891
primary pancreatic ductal adenocarcinoma 5 | 1,109
tuberculosis and treatment for 6 months 5 | 409
Alzheimer's disease 4 | 658
Dull intelligence 4 | 645
Dysarthria 4 | 192
Epilepsy 4 | 792
Hypertension 4 | 396
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Muscle hypotonia 4 | 571
Neurodegenerative disease 4 | 414
Osteoporosis 4 | 363
Parkinson's disease 4 | 392
Poor school performance 4 | 645
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
dermatomyositis 4 | 966
gastric carcinoma 4 | 807
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
Cognitive delay 3 | 608
Dementia 3 | 175
Endometrial cancer 3 | 311
Global developmental delay 3 | 608
Hyperreflexia 3 | 209
Hypertensive disease 3 | 292
Infantile onset 3 | 238
Liver cancer 3 | 604
Mental and motor retardation 3 | 608
Obesity 3 | 678
Peripheral vascular disease 3 | 87
Progressive disorder 3 | 142
Prostatic Neoplasms 3 | 495
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
chronic rhinosinusitis 3 | 512
gastric cancer 3 | 459
nasopharyngeal carcinoma 3 | 1,058

Tissue

Blood and immune system 61 | 16,909
Digestive Tract 61 | 17,369
Endocrine System 61 | 18,159
Female tissues 61 | 17,400
Liver and Pancreas 60 | 16,750
Male tissues 60 | 17,142
Nervous System 59 | 16,725
Respiratory system 59 | 16,393
Skin and soft tissues 59 | 17,230
Urinary Tract 59 | 16,678
Cardiovascular System 58 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 14 | 4,145
Transcription Factor 5 | 1,400
Transporter 4 | 473
Epigenetic 3 | 242
Ion Channel 2 | 344
Kinase 2 | 634
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -1.07328 11.4 100
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Phospholipid-transporting ATPase IA ATP8A1 Tbio Transporter -1.56158 35.5 43
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
Protein arginine N-methyltransferase 7 PRMT7 Tchem Epigenetic -1.32370 24.3 163
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
MDS1 and EVI1 complex locus protein MDS1 MECOM Tbio Non-IDG -1.84060 124.5 0