Development Level

Tbio 19 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased eosinophil cell numb... 24 | 24
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 18 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
medulloblastoma, large-cell 9 | 6,241
primitive neuroectodermal tumor 8 | 3,035
group 3 medulloblastoma 7 | 4,104
non-small cell lung cancer 7 | 2,890
Kidney cancer 6 | 2,613
ependymoma 6 | 4,679
psoriasis 6 | 6,694
tuberculosis 6 | 2,010
adult high grade glioma 5 | 3,801
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
spina bifida 5 | 1,074
Breast cancer 4 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
Melanoma 3 | 711
Pick disease 3 | 1,894
Strabismus 3 | 270
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
Adenoma 2 | 167
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Byzanthine arch palate 2 | 194
Cancer 2 | 2,499
Cardiomegaly 2 | 116
Cardiovascular system disease 2 | 246
Cataract 2 | 297
Depressive disorder 2 | 409
Dry skin 2 | 75
Epilepsy 2 | 792
Glaucoma 2 | 239
Hair shaft abnormalities 2 | 30
Hyperpigmented macules 2 | 42
Intellectual disability 2 | 1,016
Lens Opacities 2 | 231
Liver Cirrhosis, Experimental 2 | 769
Low Vision 2 | 174
Mental Depression 2 | 333
Nonsyndromic deafness 2 | 142
Nystagmus 2 | 317
Osteoarthritis 2 | 184
Palmoplantar keratosis 2 | 74
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Schizophrenia 2 | 1,160
Seizures 2 | 596
Sensorineural hearing loss 2 | 106
Short stature 2 | 531
Skin cancer 2 | 469
Visual Impairment 2 | 174
Xerosis 2 | 75
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
hair abnormalities (non-specific) 2 | 30
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
ulcerative colitis 2 | 1,819
Aggressive systemic mastocytosis 1 | 20
Anal mucosal leukoplakia 1 | 2
Autosomal dominant late onset Parkinson disease 1 | 7
Cardiomyopathy, right ventricular 1 | 7
Cleft uvula 1 | 27
Congenital pectus carinatum 1 | 52
Darier Disease 1 | 1
Darier-White Disease 1 | 1
Dent disease 1 | 18
Diabetic Cardiomyopathies 1 | 10
Diastema of Teeth 1 | 4
Enlarged vestibular aqueduct 1 | 10
Loeys-Dietz syndrome 4 1 | 4
Mast cell leukemia 1 | 13
Memory Disorders 1 | 40
Metabolic Syndrome 1 | 20
Nance-Horan syndrome 1 | 25
Neuroleptic malignant syndrome 1 | 9
Photosensitivity of skin 1 | 51
Postnatal microcephaly 1 | 24
Subungual hyperkeratotic fragments 1 | 1
Tooth, Supernumerary 1 | 7
X-linked acrogigantism due to Xq26 microduplication 1 | 2

Tissue

Nervous System 24 | 16,725
Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Respiratory system 22 | 16,393
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 3 | 4,145
GPCR 2 | 408
Kinase 2 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Seizure 6-like protein SEZ6L Tbio Non-IDG -0.86297 6.90 49
Mastermind-like domain-containing protein 1 MAMLD1 Tbio Non-IDG -1.97732 91.2 52
WAP four-disulfide core domain protein 1 WFDC1 Tbio Non-IDG -1.94592 87.9 127
Protein Shroom4 SHROOM4 Tbio Non-IDG -0.60096 4.12 8
RING finger protein 37 UBOX5 Tbio Non-IDG -0.03779 0.72 104
Lipopolysaccharide-binding protein LBP Tbio Non-IDG -2.61682 357.2 225
Gap junction beta-3 protein GJB3 Tbio Non-IDG -2.13572 133.9 212
Transforming growth factor beta-3 TGFB3 Tbio Non-IDG -3.02749 1062.5 308