Development Level

Tbio 14 | 10,625
Tdark 6 | 7,003
Tchem 3 | 1,890
Tclin 1 | 602

IMPC Term

decreased effector memory CD8-... 24 | 24
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 17 | 8,484
glioblastoma 11 | 5,572
psoriasis 11 | 6,685
medulloblastoma, large-cell 10 | 6,234
atypical teratoid / rhabdoid tumor 9 | 4,369
osteosarcoma 9 | 7,933
Multiple myeloma 7 | 1,327
lung cancer 7 | 4,466
pediatric high grade glioma 7 | 2,712
primitive neuroectodermal tumor 7 | 3,031
astrocytic glioma 6 | 2,241
group 3 medulloblastoma 6 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
ulcerative colitis 6 | 2,087
invasive ductal carcinoma 5 | 2,950
oligodendroglioma 5 | 2,849
Breast cancer 4 | 3,094
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
juvenile dermatomyositis 4 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pilocytic astrocytoma 4 | 3,086
tuberculosis 4 | 1,557
Cancer 3 | 2,346
Carcinoma 3 | 2,147
Crohn's disease 3 | 304
Intellectual disability 3 | 573
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
lung carcinoma 3 | 2,844
medulloblastoma 3 | 1,524
non-small cell lung cancer 3 | 2,798
pancreatic cancer 3 | 2,300
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 1,511
primary Sjogren syndrome 3 | 789
spina bifida 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 644
Amyotrophic Lateral Sclerosis 2 | 431
Atopic dermatitis 2 | 944
Crohn Disease 2 | 97
IGA Glomerulonephritis 2 | 454
MYELODYSPLASTIC SYNDROME 2 | 36
Posterior amorphous corneal dystrophy 2 | 9
Rheumatoid Arthritis 2 | 1,160
active Crohn's disease 2 | 918
adult high grade glioma 2 | 2,148
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
dermatomyositis 2 | 933
ependymoma 2 | 2,514
nasopharyngeal carcinoma 2 | 1,056
posterior fossa group B ependymoma 2 | 1,530
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis and treatment for 6 months 2 | 686
Acquired metabolic disease 1 | 267
Anemia 1 | 252
Autistic Disorder 1 | 320
Bipolar Disorder 1 | 266
Brain Ischemia 1 | 87
Campylobacteriosis 1 | 12
Cardiovascular system disease 1 | 194
Cerebrovascular disease 1 | 231
Congenital disorder of glycosylation 1 | 53
Craniofacial Abnormalities 1 | 147
Dementia 1 | 129
Dental caries 1 | 67
Diabetes Mellitus, Insulin-Dependent 1 | 76
Epilepsy 1 | 346
Fragile X syndrome 1 | 31
Glaucoma 1 | 134
Hemolytic anemia 1 | 66
Huntington's disease 1 | 72
Immune system cancer 1 | 38
Inflammatory Bowel Diseases 1 | 87
Juvenile myoclonic epilepsy 1 | 17
Lung Neoplasms 1 | 171
Mammary Neoplasms 1 | 410
Multiple Sclerosis 1 | 498
Myeloma 1 | 3
Peripheral Neuropathy 1 | 303
Peripheral T-cell lymphoma 1 | 24
Peripheral vascular disease 1 | 90
Polycystic Ovary Syndrome 1 | 332
Renal Cell Carcinoma 1 | 199
Sensorineural hearing loss 1 | 107
Thalassemia 1 | 46
Thyrotoxicosis 1 | 38
Toxic encephalopathy 1 | 131
Vitiligo 1 | 71
chronic rhinosinusitis 1 | 512
hereditary spastic paraplegia 1 | 313
non-inflammatory breast cancer 1 | 208
pancreatic carcinoma 1 | 567
systemic lupus erythematosus 1 | 156
type II diabetes mellitus and post-ischemic heart failure 1 | 89

Tissue

Digestive Tract 24 | 18,473
Endocrine System 24 | 18,512
Liver and Pancreas 24 | 18,136
Nervous System 24 | 18,561
Skin and soft tissues 24 | 18,115
Urinary Tract 24 | 18,444
Blood and immune system 23 | 17,995
Cardiovascular System 23 | 17,958
Female tissues 23 | 18,647
Male tissues 23 | 17,969
Respiratory system 23 | 17,484

Target Family

Non-IDG 11 | 11,971
Enzyme 8 | 4,146
Transcription Factor 3 | 1,400
Epigenetic 2 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bromodomain-containing protein 2 BRD2 Tchem Epigenetic -2.42927 0.00000 306
ATP synthase F(0) complex subunit B1, mitochondrial ATP5F1 Tbio Enzyme -0.80065 5.85 92
DNA (cytosine-5)-methyltransferase 3A DNMT3A Tclin Epigenetic -2.80919 625.6 631
SLIT and NTRK-like protein 4 SLITRK4 Tbio Non-IDG -0.13951 1.24 161
Ubiquitin-conjugating enzyme E2 G1 UBE2G1 Tbio Non-IDG -0.72379 5.55 133
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.78056 77.3 159
HBS1-like protein HBS1L Tbio Non-IDG -2.49189 316.2 144
Conserved oligomeric Golgi complex subunit 6 COG6 Tbio Non-IDG -1.56291 38.9 67
Interferon regulatory factor 5 IRF5 Tbio Transcription Factor -2.27733 219.8 311
Ras-related protein Rab-17 RAB17 Tbio Enzyme -1.15314 20.8 133