Development Level

Tbio 5 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

decreased coping response 8 | 8
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 6 | 11,493
atypical teratoid / rhabdoid tumor 4 | 5,112
non-small cell lung cancer 4 | 2,890
psoriasis 4 | 6,694
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
primitive neuroectodermal tumor 3 | 3,035
Breast cancer 2 | 3,578
Cardiomyopathy, Dilated 2 | 83
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Pick disease 2 | 1,894
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
pancreatic cancer 2 | 2,398
ANONYCHIA 1 | 20
Afro-textured hair 1 | 13
Alexander disease 1 | 11
Alopecia 1 | 115
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Astigmatism 1 | 54
Atopic dermatitis 1 | 952
Autosomal dominant Robinow syndrome 1 1 | 15
Babinski Reflex 1 | 100
Blindness 1 | 88
Cancer 1 | 2,499
Cardiac Arrhythmia 1 | 103
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Cardiovascular system disease 1 | 246
Cerebellar Dysmetria 1 | 56
Ciliopathy 1 | 71
Congestive heart failure 1 | 113
Coronary artery disease 1 | 268
Curly hair (finding) 1 | 14
Dilated cardiomyopathy 1 | 56
Dizziness 1 | 26
Down syndrome 1 | 499
Dystrophia unguium 1 | 53
Fragile skin 1 | 18
Globe disease 1 | 67
Guillain-Barre syndrome 1 | 14
Heart failure 1 | 162
Hyperhidrosis disorder 1 | 81
Hyperopia 1 | 70
Increased sweating 1 | 81
Kinky hair texture 1 | 13
Lewy Body Disease 1 | 21
Liver diseases 1 | 87
Macroglobulinemia 1 | 18
Metachromatic leukodystrophy 1 | 14
Monoclonal gammopathy of uncertain significance 1 | 4
Multiple Sclerosis 1 | 540
Myocardial Infarction 1 | 151
Nappy hair texture 1 | 13
Neuronal ceroid lipofuscinosis 1 1 | 15
Oral mucosal blistering 1 | 10
POEMS syndrome 1 | 6
Palmoplantar keratosis 1 | 74
Paraparesis, Spastic 1 | 16
Parkinson Disease 1 | 64
Polyneuropathy 1 | 64
Reduced visual acuity 1 | 63
Retinitis pigmentosa 28 1 | 19
Skin Erosion 1 | 12
Sparse eyebrow 1 | 42
Sparse scalp hair 1 | 42
Sweating 1 | 81
Syncope 1 | 22
Vascular disease 1 | 319
Ventricular arrhythmia 1 | 27
Vertigo 1 | 29
Waldenstrons macroglobulinemia 1 | 765
Wooly hair 1 | 17
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
astrocytoma 1 | 1,146
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
cone-rod dystrophy 1 | 59
fibroadenoma 1 | 559
hereditary spastic paraplegia 1 | 318
inflammatory breast cancer 1 | 286
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
progressive supranuclear palsy 1 | 676
tuberculosis 1 | 2,010

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 2 | 4,145

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein FAM161A FAM161A Tbio Non-IDG -1.10138 14.2 50
Transcription elongation factor 1 homolog ELOF1 Tdark Non-IDG -0.30103 2.00 59
Ribosome biogenesis protein WDR12 WDR12 Tbio Non-IDG -1.28968 20.5 125
Junction plakoglobin JUP Tbio Non-IDG -2.01808 101.8 719
Fatty acyl-CoA reductase 2 FAR2 Tbio Enzyme -1.12944 12.5 66
Heat shock protein beta-2 HSPB2 Tbio Non-IDG -2.87015 760.3 474
Poly [ADP-ribose] polymerase 8 PARP8 Tdark Enzyme 0.38 0.30 89
Myelin-associated glycoprotein MAG Tchem Non-IDG -2.95044 775.0 257