Development Level

Tbio 59 | 11,445
Tchem 11 | 1,598
Tdark 5 | 6,588
Tclin 4 | 613

IMPC Phenotype

decreased circulating triglyce... 79 | 79
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 56 | 11,493
osteosarcoma 41 | 7,950
ovarian cancer 39 | 8,520
psoriasis 35 | 6,694
atypical teratoid / rhabdoid tumor 30 | 5,112
medulloblastoma, large-cell 29 | 6,241
glioblastoma 27 | 5,792
lung cancer 26 | 4,740
ependymoma 23 | 4,679
Breast cancer 22 | 3,578
group 3 medulloblastoma 22 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
adult high grade glioma 18 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
Astrocytoma, Pilocytic 16 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
primitive neuroectodermal tumor 16 | 3,035
oligodendroglioma 15 | 2,850
pancreatic cancer 15 | 2,398
malignant mesothelioma 14 | 3,232
subependymal giant cell astrocytoma 14 | 2,287
Pick disease 13 | 1,894
non-small cell lung cancer 13 | 2,890
ulcerative colitis 13 | 1,819
Cancer 12 | 2,499
astrocytic glioma 12 | 2,597
invasive ductal carcinoma 12 | 2,951
lung carcinoma 12 | 2,843
Kidney cancer 11 | 2,613
Autosomal recessive predisposition 10 | 1,442
interstitial cystitis 10 | 2,312
lung adenocarcinoma 10 | 2,716
spina bifida 10 | 1,074
tuberculosis 10 | 2,010
Multiple myeloma 9 | 1,332
Rheumatoid arthritis 9 | 1,191
diabetes mellitus 9 | 1,728
ductal carcinoma in situ 9 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pituitary cancer 9 | 1,972
primary pancreatic ductal adenocarcinoma 9 | 1,109
Alzheimer's disease 8 | 658
Schizophrenia 8 | 1,160
breast carcinoma 8 | 1,638
group 4 medulloblastoma 8 | 1,855
adrenocortical carcinoma 7 | 1,428
nasopharyngeal carcinoma 7 | 1,058
esophageal adenocarcinoma 6 | 737
gastric cancer 6 | 459
non primary Sjogren syndrome sicca 6 | 891
progressive supranuclear palsy 6 | 676
Cognitive delay 5 | 608
Coronary artery disease 5 | 268
Epilepsy 5 | 792
Global developmental delay 5 | 608
Hypertension 5 | 396
Liver Cirrhosis, Experimental 5 | 769
Mental and motor retardation 5 | 608
Obesity 5 | 678
aldosterone-producing adenoma 5 | 665
cystic fibrosis 5 | 1,696
fibroadenoma 5 | 559
juvenile dermatomyositis 5 | 1,187
tuberculosis and treatment for 6 months 5 | 409
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Cataract 4 | 297
Down syndrome 4 | 499
Endometriosis 4 | 540
Intellectual disability 4 | 1,016
Mammary Neoplasms 4 | 425
Muscle hypotonia 4 | 571
Neurodegenerative disease 4 | 414
Nystagmus 4 | 317
Osteoporosis 4 | 363
Parkinson's disease 4 | 392
Polycystic ovary syndrome 4 | 360
Short stature 4 | 531
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
dermatomyositis 4 | 966
hepatocellular carcinoma 4 | 547
posterior fossa group B ependymoma 4 | 416
Crohn's disease 3 | 321
Failure to gain weight 3 | 365
Glaucoma 3 | 239
Kidney disease 3 | 430
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
Strabismus 3 | 270
chronic lymphosyte leukemia 3 | 204
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 79 | 17,369
Endocrine System 79 | 18,159
Skin and soft tissues 79 | 17,230
Male tissues 78 | 17,142
Female tissues 77 | 17,400
Urinary Tract 77 | 16,678
Liver and Pancreas 76 | 16,750
Nervous System 76 | 16,725
Blood and immune system 75 | 16,909
Respiratory system 75 | 16,393
Cardiovascular System 71 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 19 | 4,145
Transcription Factor 11 | 1,400
Ion Channel 2 | 344
Transporter 2 | 473
Kinase 1 | 634
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.98202 97.3 170
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Protein FAM83G FAM83G Tbio Non-IDG -1.07402 11.5 72
NEDD4 family-interacting protein 2 NDFIP2 Tbio Non-IDG -0.67951 5.49 37
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
ETS domain-containing transcription factor ERF ERF Tbio Transcription Factor -2.42588 268.8 257
Plexin-B2 PLXNB2 Tbio Non-IDG -1.25236 17.4 82
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25