Development Level

Tbio 37 | 11,445
Tdark 8 | 6,588
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased circulating total pr... 49 | 49
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 36 | 11,493
osteosarcoma 30 | 7,950
psoriasis 27 | 6,694
ovarian cancer 26 | 8,520
atypical teratoid / rhabdoid tumor 21 | 5,112
medulloblastoma, large-cell 18 | 6,241
lung cancer 17 | 4,740
Breast cancer 15 | 3,578
group 3 medulloblastoma 15 | 4,104
ependymoma 14 | 4,679
glioblastoma 13 | 5,792
malignant mesothelioma 12 | 3,232
Kidney cancer 11 | 2,613
Pick disease 11 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
adult high grade glioma 10 | 3,801
oligodendroglioma 10 | 2,850
pancreatic cancer 10 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
primitive neuroectodermal tumor 10 | 3,035
lung adenocarcinoma 9 | 2,716
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Astrocytoma, Pilocytic 7 | 3,081
Cancer 7 | 2,499
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
non-small cell lung cancer 7 | 2,890
primary pancreatic ductal adenocarcinoma 7 | 1,109
spina bifida 7 | 1,074
group 4 medulloblastoma 6 | 1,855
lung carcinoma 6 | 2,843
progressive supranuclear palsy 6 | 676
Alzheimer's disease 5 | 658
Rheumatoid arthritis 5 | 1,191
adrenocortical carcinoma 5 | 1,428
cutaneous lupus erythematosus 5 | 1,057
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Down syndrome 4 | 499
Kidney disease 4 | 430
Multiple myeloma 4 | 1,332
Schizophrenia 4 | 1,160
pediatric high grade glioma 4 | 1,064
Concave bridge of nose 3 | 195
Cryptorchidism 3 | 296
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Failure to gain weight 3 | 365
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Melanoma 3 | 711
Pediatric failure to thrive 3 | 365
Skin cancer 3 | 469
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
tuberculosis and treatment for 6 months 3 | 409
Alopecia 2 | 115
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Blepharoptosis 2 | 231
Coronary artery disease 2 | 268
Depressive disorder 2 | 409
Endometrial cancer 2 | 311
Hepatomegaly 2 | 285
Hydronephrosis 2 | 89
Liver Cirrhosis, Experimental 2 | 769
Lymphopenia 2 | 67
Malformed pinnae 2 | 37
Multiple Sclerosis 2 | 540
Nephrocalcinosis 2 | 35
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Strabismus 2 | 270
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
glioblastoma multiforme 2 | 142
hepatocellular carcinoma 2 | 547
juvenile dermatomyositis 2 | 1,187
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 49 | 18,159
Male tissues 49 | 17,142
Urinary Tract 49 | 16,678
Blood and immune system 48 | 16,909
Cardiovascular System 48 | 15,192
Digestive Tract 48 | 17,369
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Nervous System 48 | 16,725
Respiratory system 47 | 16,393
Skin and soft tissues 47 | 17,230

Target Family

Non-IDG 26 | 12,091
Enzyme 14 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Transporter 2 | 473
GPCR 1 | 408
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.98202 97.3 170
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
N-acetyltransferase ESCO1 ESCO1 Tbio Enzyme -1.65145 44.6 49
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Putative ADP-ribosylation factor-like protein 5C ARL5C Tdark Enzyme 0.00000 1.00 39
Centromere protein J CENPJ Tbio Non-IDG -1.79588 59.0 102
Transmembrane protein 116 TMEM116 Tdark Non-IDG 1.00 0.10 14