Development Level

Tbio 18 | 11,445
Tchem 5 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

IMPC Phenotype

decreased circulating phosphat... 27 | 27
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 18 | 11,493
osteosarcoma 16 | 7,950
medulloblastoma, large-cell 13 | 6,241
ovarian cancer 12 | 8,520
group 3 medulloblastoma 9 | 4,104
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
ependymoma 7 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Astrocytoma, Pilocytic 6 | 3,081
invasive ductal carcinoma 6 | 2,951
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Spontaneous abortion 3 | 113
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
Abnormality of creatine metabolism 2 | 4
Abortion, Spontaneous 2 | 109
Acquired metabolic disease 2 | 336
Adenoma 2 | 167
Alkaline phosphatase serum increased 2 | 29
Alopecia 2 | 115
Autistic Disorder 2 | 364
Bone pain 2 | 42
Cerebrovascular disease 2 | 238
Chronic obstructive pulmonary disease 2 | 184
Coronary artery disease 2 | 268
Crohn's disease 2 | 321
Duchenne muscular dystrophy 2 | 601
Electrocardiogram abnormal 2 | 81
Failure to gain weight 2 | 365
Femoral bowing 2 | 20
Fibular bowing 2 | 5
Frontal bossing 2 | 157
Genu varum 2 | 29
Hypercalcemia 2 | 59
Hyperparathyroidism 2 | 48
Hyperphosphatemia 2 | 32
Hypertension 2 | 396
Hypophosphatemia 2 | 40
Increased serum parathyroid hormone 2 | 14
Intellectual disability 2 | 1,016
Melanoma 2 | 711
Metaphyseal irregularity 2 | 23
Necrosis 2 | 53
Nephrocalcinosis 2 | 35
Osteomalacia 2 | 35
Osteoporosis 2 | 363
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Rickets 2 | 49
Schizophrenia 2 | 1,160
Short stature 2 | 531
Tibial bowing 2 | 19
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
cystic fibrosis 2 | 1,696
interstitial cystitis 2 | 2,312
interstitial lung disease 2 | 298
mucosa-associated lymphoid tissue lymphoma 2 | 484
nephrosclerosis 2 | 333
pancreatic cancer 2 | 2,398
ulcerative colitis 2 | 1,819
Decreased fertility in females 1 | 20
Elevated follicle stimulating hormone 1 | 15
Elevated luteinizing hormone 1 | 14
Extrinsic allergic alveolitis 1 | 6
Hypoplasia of vagina 1 | 14
Joint swelling 1 | 26
Rudimentary vagina 1 | 14
Thrombotic thrombocytopenic purpura 1 | 14

Tissue

Endocrine System 27 | 18,159
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Urinary Tract 26 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 14 | 12,091
Enzyme 11 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
E3 ubiquitin ligase RNF157 RNF157 Tbio Non-IDG 0.11 1.20 96
Glutathione S-transferase C-terminal domain-containing protein GSTCD Tbio Enzyme -0.63267 3.65 59
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.34742 219.1 219
Matrix metalloproteinase-15 MMP15 Tchem Enzyme -1.69065 43.4 351
Spermatogenesis-associated protein 5 SPATA5 Tbio Enzyme -2.18481 147.8 33
Lysine-specific demethylase 2B KDM2B Tchem Epigenetic -1.56328 41.7 248
Phospholipase D3 PLD3 Tbio Enzyme -1.77419 62.1 99
Integrator complex subunit 6-like INTS6L Tdark Non-IDG 0.39 0.32 28
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369