Development Level

Tbio 58 | 11,445
Tdark 11 | 6,588
Tchem 7 | 1,598

IMPC Phenotype

decreased circulating insulin ... 76 | 76
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 44 | 8,520
Carcinoma 43 | 11,493
osteosarcoma 42 | 7,950
psoriasis 36 | 6,694
group 3 medulloblastoma 24 | 4,104
glioblastoma 23 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
atypical teratoid / rhabdoid tumor 22 | 5,112
ependymoma 22 | 4,679
Breast cancer 21 | 3,578
lung cancer 21 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
medulloblastoma, large-cell 19 | 6,241
oligodendroglioma 18 | 2,850
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
invasive ductal carcinoma 16 | 2,951
malignant mesothelioma 16 | 3,232
primitive neuroectodermal tumor 16 | 3,035
pancreatic cancer 15 | 2,398
non-small cell lung cancer 14 | 2,890
Cancer 13 | 2,499
Pick disease 13 | 1,894
adult high grade glioma 13 | 3,801
lung carcinoma 13 | 2,843
pituitary cancer 13 | 1,972
subependymal giant cell astrocytoma 13 | 2,287
Kidney cancer 12 | 2,613
interstitial cystitis 12 | 2,312
astrocytic glioma 11 | 2,597
active Crohn's disease 10 | 922
lung adenocarcinoma 10 | 2,716
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
Schizophrenia 9 | 1,160
acute quadriplegic myopathy 9 | 1,158
cystic fibrosis 8 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
primary pancreatic ductal adenocarcinoma 8 | 1,109
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
cutaneous lupus erythematosus 7 | 1,057
diabetes mellitus 7 | 1,728
ductal carcinoma in situ 7 | 1,745
spina bifida 7 | 1,074
Atopic dermatitis 6 | 952
Multiple myeloma 6 | 1,332
astrocytoma 6 | 1,146
gastric carcinoma 6 | 807
juvenile dermatomyositis 6 | 1,187
mucosa-associated lymphoid tissue lymphoma 6 | 484
Alzheimer's disease 5 | 658
Autosomal recessive predisposition 5 | 1,442
active ulcerative colitis 5 | 764
chronic rhinosinusitis 5 | 512
group 4 medulloblastoma 5 | 1,855
pediatric high grade glioma 5 | 1,064
Acquired metabolic disease 4 | 336
Atherosclerosis 4 | 291
Autistic Disorder 4 | 364
Bladder Neoplasm 4 | 112
Depressive disorder 4 | 409
Diarrhea 4 | 253
Duchenne muscular dystrophy 4 | 601
Epilepsy 4 | 792
Kidney disease 4 | 430
Multiple Sclerosis 4 | 540
Osteoporosis 4 | 363
Rheumatoid arthritis 4 | 1,191
Urinary Bladder Neoplasms 4 | 114
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
chronic lymphosyte leukemia 4 | 204
esophageal adenocarcinoma 4 | 737
non primary Sjogren syndrome sicca 4 | 891
posterior fossa group A ependymoma 4 | 468
progressive supranuclear palsy 4 | 676
tuberculosis and treatment for 6 months 4 | 409
Bipolar Disorder 3 | 666
Cognitive delay 3 | 608
Coronary artery disease 3 | 268
Down syndrome 3 | 499
Endometriosis 3 | 540
Hypertension 3 | 396
Lens Opacities 3 | 231
Mental and motor retardation 3 | 608
Prostatic Neoplasms 3 | 495
Reperfusion Injury 3 | 86
Seizures 3 | 596
Stomach Neoplasms 3 | 300
Vascular disease 3 | 319
dermatomyositis 3 | 966
fibroadenoma 3 | 559
gastric cancer 3 | 459
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333
pancreatic carcinoma 3 | 562
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735

Tissue

Digestive Tract 75 | 17,369
Female tissues 74 | 17,400
Male tissues 74 | 17,142
Skin and soft tissues 72 | 17,230
Urinary Tract 72 | 16,678
Endocrine System 71 | 18,159
Blood and immune system 69 | 16,909
Liver and Pancreas 68 | 16,750
Nervous System 68 | 16,725
Respiratory system 68 | 16,393
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 46 | 12,091
Enzyme 18 | 4,145
Transcription Factor 7 | 1,400
GPCR 2 | 408
Ion Channel 2 | 344
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caskin-2 CASKIN2 Tdark Non-IDG -0.21450 1.97 118
Caskin-1 CASKIN1 Tdark Non-IDG -0.63111 5.31 22
Methyltransferase-like 26 METTL26 Tdark Non-IDG 0.00000 58
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Protocadherin-18 PCDH18 Tbio Non-IDG -0.69395 5.31 87
Na(+)/H(+) exchange regulatory cofactor NHE-RF4 PDZD3 Tbio Non-IDG -0.76581 6.17 121
Double zinc ribbon and ankyrin repeat-containing protein 1 DZANK1 Tdark Non-IDG 0.04 1.29 19
Exosome complex exonuclease RRP44 DIS3 Tbio Enzyme -1.80730 64.2 141
Transmembrane protein 106B TMEM106B Tbio Non-IDG -1.54017 36.2 87
Platelet basic protein PPBP Tbio Non-IDG -3.18788 1559.1 453