Development Level

Tbio 24 | 11,445
Tchem 8 | 1,598
Tdark 6 | 6,588
Tclin 1 | 613

IMPC Phenotype

decreased circulating creatini... 39 | 39
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 22 | 11,493
ovarian cancer 21 | 8,520
osteosarcoma 19 | 7,950
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
ependymoma 11 | 4,679
lung cancer 11 | 4,740
psoriasis 11 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
primitive neuroectodermal tumor 10 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Cancer 8 | 2,499
adult high grade glioma 8 | 3,801
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
Astrocytoma, Pilocytic 7 | 3,081
group 4 medulloblastoma 7 | 1,855
malignant mesothelioma 6 | 3,232
ulcerative colitis 6 | 1,819
Kidney cancer 5 | 2,613
Obesity 5 | 678
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
ductal carcinoma in situ 5 | 1,745
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
tuberculosis 5 | 2,010
Breast cancer 4 | 3,578
diabetes mellitus 4 | 1,728
pancreatic cancer 4 | 2,398
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
Atopic dermatitis 3 | 952
Autistic Disorder 3 | 364
Cerebellar Ataxia 3 | 304
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Hypersensitivity reaction type II disease 3 | 253
Intellectual disability 3 | 1,016
Mental and motor retardation 3 | 608
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
acute myeloid leukemia 3 | 783
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
inflammatory breast cancer 3 | 286
lung adenocarcinoma 3 | 2,716
oligodendroglioma 3 | 2,850
Asthma 2 | 385
Bipolar Disorder 2 | 666
Blind Vision 2 | 111
Blindness, Legal 2 | 110
Brain Ischemia 2 | 110
Cerebrovascular disease 2 | 238
Cholestasis 2 | 155
Coronary artery disease 2 | 268
Crohn's disease 2 | 321
Duchenne muscular dystrophy 2 | 601
Hepatomegaly 2 | 285
Hyperreflexia 2 | 209
Hypersensitivity 2 | 63
Hypertension 2 | 396
Hypoplasia of corpus callosum 2 | 90
Hypothyroidism 2 | 122
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Malaria 2 | 160
Mental Depression 2 | 333
Neurodegenerative disease 2 | 414
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Pachygyria 2 | 41
Paraplegia 2 | 74
Prostatic Neoplasms 2 | 495
Severe mental retardation (I.Q. 20-34) 2 | 99
Skeletal muscle atrophy 2 | 139
Upward slant of palpebral fissure 2 | 75
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
limb girdle muscular dystrophy 2A 2 | 213
medulloblastoma 2 | 720
muscle degeneration 2 | 139
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
tuberculosis and treatment for 3 months 2 | 179

Tissue

Digestive Tract 39 | 17,369
Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Liver and Pancreas 38 | 16,750
Blood and immune system 36 | 16,909
Male tissues 36 | 17,142
Skin and soft tissues 36 | 17,230
Nervous System 35 | 16,725
Respiratory system 35 | 16,393
Cardiovascular System 34 | 15,192
Urinary Tract 34 | 16,678

Target Family

Non-IDG 19 | 12,091
Enzyme 10 | 4,145
Kinase 3 | 634
GPCR 2 | 408
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,3-galactosyltransferase 1 B3GALT1 Tbio Enzyme -0.68296 3.85 66
Kelch-like protein 21 KLHL21 Tbio Non-IDG -0.32074 2.17 65
Non-lysosomal glucosylceramidase GBA2 Tchem Enzyme -1.62330 43.1 59
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47
Dysbindin domain-containing protein 2 DBNDD2 Tdark Non-IDG 0.23 0.66 28
Follistatin-related protein 1 FSTL1 Tbio Non-IDG -1.98038 117.5 265
N-formyl peptide receptor 3 FPR3 Tchem GPCR -1.41613 24.4 247
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184
Syntaxin-8 STX8 Tbio Non-IDG -2.59234 391.5 134
Protein angel homolog 1 ANGEL1 Tbio Non-IDG -0.17609 1.15 94