Development Level

Tbio 22 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

decreased circulating chloride... 30 | 30
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 18 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 12 | 8,520
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
lung cancer 10 | 4,740
medulloblastoma, large-cell 10 | 6,241
psoriasis 10 | 6,694
lung adenocarcinoma 8 | 2,716
non-small cell lung cancer 8 | 2,890
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
malignant mesothelioma 7 | 3,232
pancreatic cancer 7 | 2,398
Cancer 6 | 2,499
Kidney cancer 6 | 2,613
Multiple myeloma 6 | 1,332
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
primary pancreatic ductal adenocarcinoma 5 | 1,109
Autosomal recessive predisposition 4 | 1,442
acute myeloid leukemia 4 | 783
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Hypertension 3 | 396
Liver Cirrhosis, Experimental 3 | 769
Obesity 3 | 678
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
group 4 medulloblastoma 3 | 1,855
non primary Sjogren syndrome sicca 3 | 891
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Abortion, Spontaneous 2 | 109
Acquired metabolic disease 2 | 336
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
COPD 2 | 118
Cardiovascular system disease 2 | 246
Cleft Lip 2 | 141
Cognitive delay 2 | 608
Endometriosis 2 | 540
Epilepsy 2 | 792
Fatty liver disease 2 | 103
Female infertility 2 | 30
Generalized muscle weakness 2 | 57
Global developmental delay 2 | 608
Hypoxia 2 | 33
Infertility, Female 2 | 28
Kidney disease 2 | 430
Mental and motor retardation 2 | 608
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Spontaneous abortion 2 | 113
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
oligodendroglioma 2 | 2,850
posterior fossa group A ependymoma 2 | 468
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis and treatment for 6 months 2 | 409
Bartter disease 1 | 13
Bartter syndrome, antenatal type 1 1 | 3
Calcium pyrophosphate deposition disease 1 | 13
Elevated plasma renin 1 | 9
Fetal polyuria 1 | 8
Hyperactive renin-angiotensin system 1 | 8
Hypochloremia (disorder) 1 | 6
Hypokalemic metabolic alkalosis 1 | 4
Impairment of urinary concentration 1 | 5
Increased urinary chloride 1 | 5
Increased urinary potassium 1 | 5
Muscle Cramp 1 | 55
Polyuria 1 | 23
Renal juxtaglomerular cell hypertrophy/hyperplasia 1 | 2
Renal potassium wasting 1 | 5
Renal salt wasting 1 | 18
Serum chloride level decreased (finding) 1 | 6
Tetanus 1 | 68
Tetany 1 | 18
Type 1 diabetes mellitus 1 | 109

Tissue

Endocrine System 30 | 18,159
Nervous System 29 | 16,725
Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678
Respiratory system 27 | 16,393
Cardiovascular System 26 | 15,192

Target Family

Non-IDG 14 | 12,091
Enzyme 12 | 4,145
Transcription Factor 2 | 1,400
Transporter 2 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 14A TMEM14A Tbio Non-IDG -0.33645 3.05 17
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.07841 114.8 103
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -1.07328 11.4 100
Matrix metalloproteinase-15 MMP15 Tchem Enzyme -1.69065 43.4 351
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Vacuole membrane protein 1 VMP1 Tbio Non-IDG -2.49755 302.1 137
Aldehyde dehydrogenase family 16 member A1 ALDH16A1 Tdark Enzyme -0.41378 2.89 74
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 KCTD10 Tbio Non-IDG -0.81230 8.68 90
Ras and Rab interactor 3 RIN3 Tbio Non-IDG -1.30417 18.7 47