Development Level

Tbio 37 | 11,178
Tchem 6 | 1,885
Tdark 3 | 6,569
Tclin 1 | 612

IMPC Phenotype

decreased circulating alanine ... 47 | 47
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 39 | 11,192
ovarian cancer 29 | 8,297
osteosarcoma 28 | 7,766
atypical teratoid / rhabdoid tumor 22 | 4,971
glioblastoma 19 | 5,635
medulloblastoma, large-cell 19 | 6,086
psoriasis 19 | 6,514
lung cancer 17 | 4,607
Astrocytoma, Pilocytic 13 | 3,006
ependymoma 13 | 4,559
Breast cancer 12 | 3,469
Kidney cancer 12 | 2,548
adult high grade glioma 12 | 3,701
non-small cell lung cancer 12 | 2,799
primitive neuroectodermal tumor 12 | 2,957
group 3 medulloblastoma 11 | 4,002
malignant mesothelioma 11 | 3,135
Pick disease 10 | 1,856
lung carcinoma 10 | 2,755
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,872
Cancer 8 | 2,388
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,204
invasive ductal carcinoma 8 | 2,867
lung adenocarcinoma 8 | 2,627
pancreatic cancer 8 | 2,322
diabetes mellitus 7 | 1,683
pituitary cancer 7 | 1,915
Waldenstrons macroglobulinemia 6 | 742
astrocytic glioma 6 | 2,530
breast carcinoma 6 | 1,589
cystic fibrosis 6 | 1,629
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,902
oligodendroglioma 6 | 2,768
subependymal giant cell astrocytoma 6 | 2,230
tuberculosis 6 | 1,963
Autistic Disorder 5 | 358
Autosomal recessive predisposition 5 | 1,407
Down syndrome 5 | 480
Intellectual disability 5 | 998
Rheumatoid arthritis 5 | 1,156
astrocytoma 5 | 1,113
esophageal adenocarcinoma 5 | 696
group 4 medulloblastoma 5 | 1,806
medulloblastoma 5 | 702
progressive supranuclear palsy 5 | 656
spina bifida 5 | 1,053
ulcerative colitis 5 | 1,765
Alzheimer's disease 4 | 640
Atopic dermatitis 4 | 915
Dull intelligence 4 | 634
Low intelligence 4 | 634
Mental Retardation 4 | 634
Mental deficiency 4 | 634
Multiple myeloma 4 | 1,296
Poor school performance 4 | 634
active ulcerative colitis 4 | 736
adrenocortical carcinoma 4 | 1,385
colon cancer 4 | 1,428
ductal carcinoma in situ 4 | 1,686
pancreatic carcinoma 4 | 555
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,911
posterior fossa group B ependymoma 4 | 406
primary Sjogren syndrome 4 | 710
sonic hedgehog group medulloblastoma 4 | 459
Acquired metabolic disease 3 | 329
Alcoholic Intoxication, Chronic 3 | 283
Attention deficit hyperactivity disorder 3 | 272
Blepharoptosis 3 | 229
Cognitive delay 3 | 596
Concave bridge of nose 3 | 191
Cryptorchidism 3 | 287
DOID:2627 3 | 89
Depressed nasal bridge 3 | 191
Depressed nasal root/bridge 3 | 191
Depressive disorder 3 | 401
Duchenne muscular dystrophy 3 | 587
Failure to gain weight 3 | 359
Global developmental delay 3 | 596
Liver Cirrhosis, Experimental 3 | 733
Low-set, posteriorly rotated ears 3 | 109
Melanoma 3 | 689
Mental Depression 3 | 325
Mental and motor retardation 3 | 596
Obesity 3 | 655
Pediatric failure to thrive 3 | 359
Polycystic ovary syndrome 3 | 348
Schizophrenia 3 | 1,136
Type 2 diabetes mellitus 3 | 268
acute quadriplegic myopathy 3 | 1,133
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 492
chronic lymphosyte leukemia 3 | 199
cutaneous lupus erythematosus 3 | 1,016
gastric cancer 3 | 445
hepatocellular carcinoma 3 | 536
interstitial cystitis 3 | 2,237
pediatric high grade glioma 3 | 1,035
primary pancreatic ductal adenocarcinoma 3 | 1,071
Bipolar Disorder 2 | 646
Vascular disease 2 | 294
dermatomyositis 2 | 941

Tissue

Endocrine System 46 | 18,159
Blood and immune system 45 | 16,909
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Nervous System 45 | 16,725
Digestive Tract 44 | 17,369
Male tissues 44 | 17,142
Respiratory system 44 | 16,393
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Cardiovascular System 43 | 15,192

Target Family

Enzyme 18 | 4,145
Non-IDG 18 | 12,091
Epigenetic 4 | 242
Transcription Factor 3 | 1,400
GPCR 2 | 408
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
tRNA methyltransferase 10 homolog A TRMT10A Tbio Enzyme -1.10123 12.2 75
Suppression of tumorigenicity 18 protein ST18 Tbio Transcription Factor -0.30549 1.95 183
Chromodomain-helicase-DNA-binding protein 7 CHD7 Tbio Epigenetic -2.91077 788.8 102
Histone-lysine N-methyltransferase KMT5B KMT5B Tbio Epigenetic -1.20275 14.3 158
Prostaglandin D2 receptor PTGDR Tclin GPCR -2.75743 541.2 147
Rho guanine nucleotide exchange factor 4 ARHGEF4 Tbio Non-IDG -1.40554 28.0 126
Peroxisomal biogenesis factor 3 PEX3 Tbio Non-IDG -1.79362 72.7 79
Phosphatidylcholine:ceramide cholinephosphotransferase 1 SGMS1 Tbio Enzyme -1.61164 41.6 0
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388