Development Level

Tbio 37 | 11,651
Tchem 6 | 1,388
Tdark 3 | 6,593
Tclin 1 | 612

IMPC Phenotype

decreased circulating alanine ... 47 | 47
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 40 | 11,493
ovarian cancer 29 | 8,520
osteosarcoma 28 | 7,950
atypical teratoid / rhabdoid tumor 22 | 5,112
medulloblastoma, large-cell 20 | 6,241
glioblastoma 19 | 5,792
psoriasis 19 | 6,694
lung cancer 17 | 4,740
Astrocytoma, Pilocytic 13 | 3,081
Kidney cancer 13 | 2,613
ependymoma 13 | 4,679
Breast cancer 12 | 3,578
adult high grade glioma 12 | 3,801
non-small cell lung cancer 12 | 2,890
primitive neuroectodermal tumor 12 | 3,035
group 3 medulloblastoma 11 | 4,104
malignant mesothelioma 11 | 3,232
Pick disease 10 | 1,894
lung carcinoma 10 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Cancer 8 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
lung adenocarcinoma 8 | 2,716
pancreatic cancer 8 | 2,398
cystic fibrosis 7 | 1,696
diabetes mellitus 7 | 1,728
pituitary cancer 7 | 1,972
Autosomal recessive predisposition 6 | 1,442
Waldenstrons macroglobulinemia 6 | 765
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Autistic Disorder 5 | 364
Down syndrome 5 | 499
Intellectual disability 5 | 1,016
Rheumatoid arthritis 5 | 1,191
astrocytoma 5 | 1,146
esophageal adenocarcinoma 5 | 737
group 4 medulloblastoma 5 | 1,855
medulloblastoma 5 | 720
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
ulcerative colitis 5 | 1,819
Alzheimer's disease 4 | 658
Atopic dermatitis 4 | 952
Dull intelligence 4 | 645
Failure to gain weight 4 | 365
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Pediatric failure to thrive 4 | 365
Poor school performance 4 | 645
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
posterior fossa group B ependymoma 4 | 416
primary Sjogren syndrome 4 | 735
sonic hedgehog group medulloblastoma 4 | 467
Acquired metabolic disease 3 | 336
Alcoholic Intoxication, Chronic 3 | 289
Attention deficit hyperactivity disorder 3 | 278
Blepharoptosis 3 | 231
Cognitive delay 3 | 608
Concave bridge of nose 3 | 195
Cryptorchidism 3 | 296
DOID:2627 3 | 94
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Global developmental delay 3 | 608
Liver Cirrhosis, Experimental 3 | 769
Low-set, posteriorly rotated ears 3 | 110
Melanoma 3 | 711
Mental Depression 3 | 333
Mental and motor retardation 3 | 608
Obesity 3 | 678
Polycystic ovary syndrome 3 | 360
Schizophrenia 3 | 1,160
Type 2 diabetes mellitus 3 | 272
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic lymphosyte leukemia 3 | 204
cutaneous lupus erythematosus 3 | 1,057
gastric cancer 3 | 459
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
Bipolar Disorder 2 | 666
dermatomyositis 2 | 966

Tissue

Endocrine System 46 | 18,159
Blood and immune system 45 | 16,909
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Nervous System 45 | 16,725
Digestive Tract 44 | 17,369
Male tissues 44 | 17,142
Respiratory system 44 | 16,393
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Cardiovascular System 43 | 15,192

Target Family

Enzyme 18 | 4,145
Non-IDG 18 | 12,091
Epigenetic 4 | 242
Transcription Factor 3 | 1,400
GPCR 2 | 408
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Transcription factor AP-4 TFAP4 Tbio Transcription Factor -1.33384 19.4 276
DnaJ homolog subfamily C member 28 DNAJC28 Tbio Non-IDG -1.07807 10.5 94
Ras-related protein Rab-32 RAB32 Tbio Enzyme -1.46660 33.4 127
Type-2 angiotensin II receptor AGTR2 Tchem GPCR -3.30172 1972.1 147
Beta-1,4-glucuronyltransferase 1 B4GAT1 Tbio Enzyme -1.18067 14.2 104
Mitochondrial 2-oxodicarboxylate carrier SLC25A21 Tbio Transporter -0.71354 3.68 112
F-box only protein 7 FBXO7 Tbio Non-IDG -2.07231 118.6 100