Development Level

Tbio 36 | 11,445
Tdark 13 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

decreased caudal vertebrae num... 53 | 53
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 38 | 11,493
ovarian cancer 31 | 8,520
osteosarcoma 30 | 7,950
psoriasis 21 | 6,694
lung cancer 19 | 4,740
glioblastoma 18 | 5,792
medulloblastoma, large-cell 18 | 6,241
atypical teratoid / rhabdoid tumor 17 | 5,112
group 3 medulloblastoma 16 | 4,104
ependymoma 14 | 4,679
primitive neuroectodermal tumor 14 | 3,035
Kidney cancer 11 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
adult high grade glioma 10 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Breast cancer 9 | 3,578
astrocytic glioma 9 | 2,597
malignant mesothelioma 9 | 3,232
oligodendroglioma 9 | 2,850
subependymal giant cell astrocytoma 9 | 2,287
Astrocytoma, Pilocytic 7 | 3,081
Pick disease 7 | 1,894
Rheumatoid arthritis 7 | 1,191
juvenile dermatomyositis 7 | 1,187
lung adenocarcinoma 7 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
ductal carcinoma in situ 6 | 1,745
invasive ductal carcinoma 6 | 2,951
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Down syndrome 5 | 499
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
acute quadriplegic myopathy 5 | 1,158
lung carcinoma 5 | 2,843
progressive supranuclear palsy 5 | 676
Atopic dermatitis 4 | 952
Cancer 4 | 2,499
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
Abnormality of metabolism/homeostasis 3 | 134
Alzheimer's disease 3 | 658
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Congenital Epicanthus 3 | 177
Duchenne muscular dystrophy 3 | 601
Intellectual disability 3 | 1,016
Liver Cirrhosis, Experimental 3 | 769
Low Vision 3 | 174
Muscle hypotonia 3 | 571
Parkinson's disease 3 | 392
Respiratory Insufficiency 3 | 132
Respiratory function loss 3 | 121
Visual Impairment 3 | 174
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
nephrosclerosis 3 | 333
pancreatic carcinoma 3 | 562
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819
Blepharoptosis 2 | 231
Broad flat nasal bridge 2 | 236
Chronic Lymphocytic Leukemia 2 | 262
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Hyperplasia of cheeks 2 | 50
Melanoma 2 | 711
Microcephaly 2 | 166
Motor delay 2 | 147
Muscle Spasticity 2 | 195
Myopia 2 | 176
Nasal bridge wide 2 | 236
No development of motor milestones 2 | 147
Seizures 2 | 596
Skin cancer 2 | 469
Strabismus 2 | 270
Substance-Related Disorders 2 | 115
Upward slant of palpebral fissure 2 | 75
Waldenstrons macroglobulinemia 2 | 765
head and neck cancer 2 | 271
hereditary spastic paraplegia 2 | 318
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
substance-related disorder 2 | 162
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 53 | 16,909
Digestive Tract 53 | 17,369
Endocrine System 53 | 18,159
Female tissues 53 | 17,400
Liver and Pancreas 53 | 16,750
Male tissues 53 | 17,142
Skin and soft tissues 53 | 17,230
Urinary Tract 53 | 16,678
Nervous System 52 | 16,725
Cardiovascular System 51 | 15,192
Respiratory system 51 | 16,393

Target Family

Non-IDG 26 | 12,091
Enzyme 13 | 4,145
Transcription Factor 5 | 1,400
Epigenetic 4 | 242
Transporter 3 | 473
GPCR 1 | 408
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dephospho-CoA kinase domain-containing protein DCAKD Tdark Enzyme 0.95 0.08 141
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47
SET domain-containing protein 4 SETD4 Tdark Epigenetic -0.13929 2.27 99
AF4/FMR2 family member 3 AFF3 Tbio Transcription Factor -1.37981 25.3 50
Homeobox and leucine zipper protein Homez HOMEZ Tbio Transcription Factor -0.84510 5.41 112
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.83079 8.71 94
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
Protein FAM160A1 FAM160A1 Tdark Non-IDG 0.00000 7
Selenocysteine insertion sequence-binding protein 2 SECISBP2 Tbio Non-IDG -1.99611 107.4 145
Nucleoside diphosphate kinase 7 NME7 Tbio Enzyme -0.83479 6.29 113