Development Level

Tbio 87 | 11,445
Tdark 19 | 6,588
Tchem 14 | 1,598
Tclin 6 | 613

Collection

GPCR: IDG Consortium (Targets) 3 | 126
RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased bone mineral density 126 | 126
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 95 | 11,493
ovarian cancer 70 | 8,520
psoriasis 56 | 6,694
glioblastoma 49 | 5,792
medulloblastoma, large-cell 48 | 6,241
osteosarcoma 48 | 7,950
atypical teratoid / rhabdoid tumor 41 | 5,112
ependymoma 36 | 4,679
lung cancer 35 | 4,740
group 3 medulloblastoma 34 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
Breast cancer 29 | 3,578
primitive neuroectodermal tumor 28 | 3,035
Cancer 25 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
Astrocytoma, Pilocytic 23 | 3,081
malignant mesothelioma 23 | 3,232
adult high grade glioma 21 | 3,801
astrocytic glioma 21 | 2,597
invasive ductal carcinoma 21 | 2,951
subependymal giant cell astrocytoma 21 | 2,287
Kidney cancer 20 | 2,613
non-small cell lung cancer 20 | 2,890
Autosomal recessive predisposition 19 | 1,442
Rheumatoid arthritis 19 | 1,191
pituitary cancer 19 | 1,972
oligodendroglioma 18 | 2,850
lung carcinoma 17 | 2,843
Pick disease 16 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
breast carcinoma 15 | 1,638
group 4 medulloblastoma 15 | 1,855
lung adenocarcinoma 15 | 2,716
pediatric high grade glioma 15 | 1,064
tuberculosis 15 | 2,010
ulcerative colitis 15 | 1,819
Intellectual disability 14 | 1,016
Obesity 13 | 678
spina bifida 13 | 1,074
colon cancer 12 | 1,478
Multiple myeloma 11 | 1,332
dermatomyositis 11 | 966
ductal carcinoma in situ 11 | 1,745
interstitial cystitis 11 | 2,312
juvenile dermatomyositis 11 | 1,187
pancreatic cancer 11 | 2,398
primary pancreatic ductal adenocarcinoma 11 | 1,109
Short stature 10 | 531
acute myeloid leukemia 10 | 783
acute quadriplegic myopathy 10 | 1,158
astrocytoma 10 | 1,146
diabetes mellitus 10 | 1,728
Muscle hypotonia 9 | 571
active ulcerative colitis 9 | 764
adrenocortical carcinoma 9 | 1,428
Dull intelligence 8 | 645
Epilepsy 8 | 792
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
active Crohn's disease 8 | 922
Atopic dermatitis 7 | 952
Breast Neoplasms 7 | 445
Down syndrome 7 | 499
Failure to gain weight 7 | 365
Mammary Neoplasms 7 | 425
Osteoporosis 7 | 363
Pediatric failure to thrive 7 | 365
nephrosclerosis 7 | 333
primary Sjogren syndrome 7 | 735
Bipolar Disorder 6 | 666
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Liver Cirrhosis, Experimental 6 | 769
Mental and motor retardation 6 | 608
Multiple Sclerosis 6 | 540
Prostatic Neoplasms 6 | 495
Seizures 6 | 596
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
gastric carcinoma 6 | 807
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
tuberculosis and treatment for 6 months 6 | 409
urothelial carcinoma 6 | 318
Acquired metabolic disease 5 | 336
Hepatomegaly 5 | 285
Hypogonadism 5 | 173
Liver cancer 5 | 604
Liver carcinoma 5 | 240
Melanoma 5 | 711
Neurodegenerative disease 5 | 414
chronic rhinosinusitis 5 | 512
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
fibroadenoma 5 | 559
progressive supranuclear palsy 5 | 676
Endometriosis 4 | 540
Schizophrenia 4 | 1,160

Tissue

Endocrine System 124 | 18,159
Digestive Tract 122 | 17,369
Liver and Pancreas 121 | 16,750
Female tissues 120 | 17,400
Skin and soft tissues 120 | 17,230
Blood and immune system 119 | 16,909
Male tissues 119 | 17,142
Nervous System 118 | 16,725
Respiratory system 118 | 16,393
Urinary Tract 117 | 16,678
Cardiovascular System 111 | 15,192

Target Family

Non-IDG 51 | 12,091
Enzyme 44 | 4,145
Transcription Factor 10 | 1,400
GPCR 6 | 408
Transporter 6 | 473
Epigenetic 5 | 242
Kinase 2 | 634
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase TRIM39 TRIM39 Tbio Enzyme -1.24729 16.2 194
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -1.07328 11.4 100
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.57250 40.4 202
COP9 signalosome complex subunit 4 COPS4 Tbio Non-IDG -0.91181 7.39 88
Probable E3 ubiquitin-protein ligase MID2 MID2 Tbio Enzyme -2.49198 303.4 152
HMG box transcription factor BBX BBX Tbio Transcription Factor -1.55048 35.3 82
Cohesin subunit SA-3 STAG3 Tbio Non-IDG -1.30055 20.0 104
Phospholipid-transporting ATPase IA ATP8A1 Tbio Transporter -1.56158 35.5 43