Development Level

Tbio 68 | 11,445
Tdark 19 | 6,588
Tchem 9 | 1,598
Tclin 5 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased body length 101 | 101
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 73 | 11,493
ovarian cancer 56 | 8,520
glioblastoma 50 | 5,792
medulloblastoma, large-cell 47 | 6,241
psoriasis 45 | 6,694
atypical teratoid / rhabdoid tumor 42 | 5,112
osteosarcoma 42 | 7,950
ependymoma 30 | 4,679
adult high grade glioma 28 | 3,801
lung cancer 28 | 4,740
malignant mesothelioma 25 | 3,232
group 3 medulloblastoma 24 | 4,104
Breast cancer 23 | 3,578
Kidney cancer 23 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Astrocytoma, Pilocytic 19 | 3,081
group 4 medulloblastoma 18 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Cancer 17 | 2,499
Pick disease 17 | 1,894
invasive ductal carcinoma 17 | 2,951
primitive neuroectodermal tumor 17 | 3,035
oligodendroglioma 15 | 2,850
pituitary cancer 15 | 1,972
astrocytic glioma 14 | 2,597
lung carcinoma 13 | 2,843
non-small cell lung cancer 13 | 2,890
colon cancer 12 | 1,478
lung adenocarcinoma 12 | 2,716
Rheumatoid arthritis 11 | 1,191
juvenile dermatomyositis 11 | 1,187
subependymal giant cell astrocytoma 11 | 2,287
astrocytoma 10 | 1,146
cystic fibrosis 10 | 1,696
interstitial cystitis 10 | 2,312
pancreatic cancer 10 | 2,398
pediatric high grade glioma 10 | 1,064
Down syndrome 9 | 499
Intellectual disability 9 | 1,016
adrenocortical carcinoma 9 | 1,428
breast carcinoma 9 | 1,638
dermatomyositis 9 | 966
ductal carcinoma in situ 9 | 1,745
primary pancreatic ductal adenocarcinoma 9 | 1,109
Obesity 8 | 678
diabetes mellitus 8 | 1,728
Atopic dermatitis 7 | 952
Autosomal recessive predisposition 7 | 1,442
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Schizophrenia 7 | 1,160
cutaneous lupus erythematosus 7 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
tuberculosis 7 | 2,010
Epilepsy 6 | 792
Liver Cirrhosis, Experimental 6 | 769
Multiple myeloma 6 | 1,332
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
acute quadriplegic myopathy 6 | 1,158
medulloblastoma 6 | 720
non primary Sjogren syndrome sicca 6 | 891
ulcerative colitis 6 | 1,819
Autistic Disorder 5 | 364
Bipolar Disorder 5 | 666
Depressive disorder 5 | 409
Muscle hypotonia 5 | 571
Short stature 5 | 531
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
spina bifida 5 | 1,074
tuberculosis and treatment for 6 months 5 | 409
Amyotrophic lateral sclerosis 4 | 451
Cryptorchidism 4 | 296
Failure to gain weight 4 | 365
Frontal bossing 4 | 157
Hyperphosphatemia 4 | 32
Hypophosphatemia 4 | 40
Liver cancer 4 | 604
Osteoporosis 4 | 363
Pediatric failure to thrive 4 | 365
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
progressive supranuclear palsy 4 | 676
urothelial carcinoma 4 | 318
Alzheimer's disease 3 | 658
Anorexia nervosa 3 | 80
Arthritis, Juvenile 3 | 126
Juvenile arthritis 3 | 126
Vascular disease 3 | 319
chronic rhinosinusitis 3 | 512
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
hepatocellular carcinoma 3 | 547
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333

Tissue

Endocrine System 100 | 18,159
Digestive Tract 98 | 17,369
Liver and Pancreas 97 | 16,750
Blood and immune system 96 | 16,909
Female tissues 96 | 17,400
Skin and soft tissues 96 | 17,230
Male tissues 95 | 17,142
Urinary Tract 95 | 16,678
Nervous System 94 | 16,725
Respiratory system 94 | 16,393
Cardiovascular System 91 | 15,192

Target Family

Non-IDG 47 | 12,091
Enzyme 31 | 4,145
Transcription Factor 7 | 1,400
Epigenetic 5 | 242
Kinase 4 | 634
Transporter 4 | 473
GPCR 1 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adherens junction-associated protein 1 AJAP1 Tbio Non-IDG -1.20907 21.2 25
Transmembrane protein 248 TMEM248 Tdark Non-IDG 0.00000 47
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.57250 40.4 202
HMG box transcription factor BBX BBX Tbio Transcription Factor -1.55048 35.3 82
Sn1-specific diacylglycerol lipase alpha DAGLA Tchem Enzyme -1.11500 11.4 129
BTB/POZ domain-containing protein 9 BTBD9 Tbio Non-IDG -1.32647 22.9 104
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
Centromere protein J CENPJ Tbio Non-IDG -1.79588 59.0 102
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128