Development Level

Tbio 4 | 10,625

IMPC Term

decreased Ly6C-positive mature... 4 | 4
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

psoriasis 4 | 6,685
lung cancer 3 | 4,473
ovarian cancer 3 | 8,492
Breast cancer 2 | 3,099
Multiple myeloma 2 | 1,328
atypical teratoid / rhabdoid tumor 2 | 4,369
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 436
glioblastoma 2 | 5,572
invasive ductal carcinoma 2 | 2,950
medulloblastoma, large-cell 2 | 6,234
non primary Sjogren syndrome sicca 2 | 840
primitive neuroectodermal tumor 2 | 3,031
ulcerative colitis 2 | 2,087
Asthma 1 | 349
Atopic dermatitis 1 | 944
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIl 1 | 1
Compartment syndrome 1 | 10
Congenital disorder of glycosylation 1 | 53
Congenital disorder of glycosylation 2L 1 | 1
Congenital disorder of glycosylation type 2L 1 | 1
Crohn's disease 1 | 304
Endometriosis 1 | 535
Hay fever 1 | 10
Hypohidrosis 1 | 13
IGA Glomerulonephritis 1 | 454
Immunodeficiency-centromeric instability-facial anomalies syndrome 4 1 | 1
Intellectual disability 1 | 573
Polycystic Ovary Syndrome 1 | 335
Poor school performance 1 | 13
Posterior amorphous corneal dystrophy 1 | 9
Precursor Cell Lymphoblastic Leukemia Lymphoma 1 | 42
Primary biliary cirrhosis 1 | 45
Rheumatoid Arthritis 1 | 1,171
Schimke immuno-osseous dysplasia 1 | 9
Shaheen syndrome 1 | 1
acute lymphocytic leukemia 1 | 25
adrenocortical carcinoma 1 | 1,427
adult high grade glioma 1 | 2,148
chronic lymphocytic leukemia 1 | 244
diabetes mellitus 1 | 1,663
esophageal adenocarcinoma 1 | 737
group 3 medulloblastoma 1 | 2,254
hepatocellular carcinoma 1 | 550
immunodeficiency-centromeric instability-facial anomalies syndrome 1 | 4
interstitial cystitis 1 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,289
lung carcinoma 1 | 2,844
malignant mesothelioma 1 | 3,163
nasopharyngeal carcinoma 1 | 1,056
non-small cell lung cancer 1 | 2,798
oligodendroglioma 1 | 2,849
osteosarcoma 1 | 7,933
pancreatic cancer 1 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pediatric high grade glioma 1 | 2,712
pilocytic astrocytoma 1 | 3,086
posterior fossa group A ependymoma 1 | 1,511
primary Sjogren syndrome 1 | 789
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 4 | 17,995
Cardiovascular System 4 | 17,958
Digestive Tract 4 | 18,473
Endocrine System 4 | 18,512
Female tissues 4 | 18,647
Liver and Pancreas 4 | 18,136
Male tissues 4 | 17,969
Nervous System 4 | 18,561
Respiratory system 4 | 17,484
Skin and soft tissues 4 | 18,115
Urinary Tract 4 | 18,444

Target Family

Non-IDG 2 | 11,969
Enzyme 1 | 4,146
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Conserved oligomeric Golgi complex subunit 6 COG6 Tbio Non-IDG -1.58322 38.9 67
Zinc finger protein Aiolos IKZF3 Tbio Transcription Factor -1.78743 55.0 277
Ubiquitin-conjugating enzyme E2 G1 UBE2G1 Tbio Non-IDG -0.81635 5.55 133
Lymphoid-specific helicase HELLS Tbio Enzyme -1.93443 89.7 162