Development Level

Tbio 17 | 10,625
Tdark 4 | 7,003
Tchem 1 | 1,890
Tclin 1 | 602

IMPC Term

decreased Ly6C low monocyte nu... 23 | 23
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 13 | 7,933
ovarian cancer 12 | 8,484
medulloblastoma, large-cell 10 | 6,234
atypical teratoid / rhabdoid tumor 6 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
Down syndrome 5 | 548
astrocytic glioma 5 | 2,241
glioblastoma 5 | 5,572
lung cancer 5 | 4,466
psoriasis 5 | 6,685
spina bifida 5 | 1,064
tuberculosis and treatment for 6 months 5 | 686
Breast cancer 4 | 3,094
active Crohn's disease 4 | 918
group 3 medulloblastoma 4 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
oligodendroglioma 4 | 2,849
pancreatic cancer 4 | 2,300
posterior fossa group B ependymoma 4 | 1,530
ulcerative colitis 4 | 2,087
Rheumatoid Arthritis 3 | 1,160
adult high grade glioma 3 | 2,148
breast carcinoma 3 | 1,614
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
invasive ductal carcinoma 3 | 2,950
lung adenocarcinoma 3 | 2,713
non-small cell lung cancer 3 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,031
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 1,557
Cancer 2 | 2,346
Intellectual disability 2 | 573
Microcephaly 2 | 149
Weight Gain 2 | 87
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,665
malignant mesothelioma 2 | 3,162
pancreatic carcinoma 2 | 567
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
primary pancreatic ductal adenocarcinoma 2 | 1,271
progressive supranuclear palsy 2 | 674
sonic hedgehog group medulloblastoma 2 | 1,482
Atopic dermatitis 1 | 944
Autistic Disorder 1 | 320
Bipolar Disorder 1 | 266
Cerebral palsy 1 | 28
Cutis laxa 1 | 28
Disease of anatomical entity 1 | 25
Early myoclonic encephalopathy 1 | 8
Essential Hypertension 1 | 82
Fundus dystrophy 1 | 77
Glaucoma 1 | 134
Hepatitis B 1 | 103
Hepatitis C 1 | 90
Hypersensitivity reaction type II disease 1 | 235
Hypothyroidism 1 | 89
Influenza 1 | 142
Leukodystrophy 1 | 30
Liver disease 1 | 219
Lupus Erythematosus, Systemic 1 | 73
Major Depressive Disorder 1 | 106
Malignant neoplasm of pancreas 1 | 14
Mental depression 1 | 58
Multiple Sclerosis 1 | 498
Muscle Weakness 1 | 92
Neurodegenerative disease 1 | 383
Paraplegia 1 | 71
Penile cancer 1 | 3
Pick disease 1 | 1,893
Quadriplegia 1 | 14
Relapsing remitting multiple sclerosis 1 | 14
Spinocerebellar ataxia type 7 1 | 13
Stuttering 1 | 18
Systemic scleroderma 1 | 66
Trichotillomania 1 | 6
Type 2 diabetes mellitus 1 | 189
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
aldosterone-producing adenoma 1 | 664
facioscapulohumeral dystrophy 1 | 286
fibroadenoma 1 | 557
glioblastoma multiforme 1 | 347
head and neck cancer 1 | 270
hepatocellular carcinoma 1 | 532
hereditary spastic paraplegia 1 | 313
inflammatory breast cancer 1 | 404
mucosa-associated lymphoid tissue lymphoma 1 | 480
nasopharyngeal carcinoma 1 | 1,056
non-small cell lung carcinoma 1 | 413
pediatric high grade glioma 1 | 2,712
substance-related disorder 1 | 105
systemic lupus erythematosus 1 | 156
uncontrolled asthma 1 | 67
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 23 | 17,995
Cardiovascular System 23 | 17,958
Digestive Tract 23 | 18,473
Endocrine System 23 | 18,512
Female tissues 23 | 18,647
Liver and Pancreas 23 | 18,136
Male tissues 23 | 17,969
Nervous System 23 | 18,561
Respiratory system 23 | 17,484
Skin and soft tissues 23 | 18,115
Urinary Tract 23 | 18,444

Target Family

Non-IDG 9 | 11,971
Enzyme 8 | 4,146
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
GPCR 1 | 406
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polypeptide N-acetylgalactosaminyltransferase 18 GALNT18 Tdark Enzyme -0.28065 3.03 33
Mediator of RNA polymerase II transcription subunit 23 MED23 Tbio Enzyme -1.41952 30.0 128
Low-density lipoprotein receptor class A domain-containing protein 4 LDLRAD4 Tbio Non-IDG -1.51136 24.6 45
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.77118 9.19 84
AP-4 complex subunit epsilon-1 AP4E1 Tdark Non-IDG -0.63202 4.65 21
Methyl-CpG-binding domain protein 1 MBD1 Tbio Transcription Factor -2.19366 164.7 282
Interferon regulatory factor 5 IRF5 Tbio Transcription Factor -2.27733 219.8 311
Unconventional myosin-X MYO10 Tbio Non-IDG -1.43593 32.9 38
Dimethylglycine dehydrogenase, mitochondrial DMGDH Tbio Enzyme -1.34540 23.0 99
Ciliogenesis-associated TTC17-interacting protein CATIP Tdark Non-IDG -0.35218 1.82 67