Development Level

Tbio 13 | 10,625
Tdark 5 | 7,003

IMPC Term

decreased Ly6C high monocyte n... 18 | 18
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 11 | 7,933
ovarian cancer 11 | 8,484
medulloblastoma, large-cell 9 | 6,234
psoriasis 8 | 6,685
atypical teratoid / rhabdoid tumor 6 | 4,369
glioblastoma 6 | 5,572
lung cancer 6 | 4,466
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
ependymoma 4 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
invasive ductal carcinoma 4 | 2,950
lung carcinoma 4 | 2,844
pediatric high grade glioma 4 | 2,712
Carcinoma 3 | 2,147
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,665
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
malignant mesothelioma 3 | 3,162
posterior fossa group B ependymoma 3 | 1,530
primitive neuroectodermal tumor 3 | 3,031
spina bifida 3 | 1,064
Intellectual disability 2 | 573
Rheumatoid Arthritis 2 | 1,160
acute myeloid leukemia 2 | 780
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
group 3 medulloblastoma 2 | 2,254
medulloblastoma 2 | 1,524
non primary Sjogren syndrome sicca 2 | 840
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
primary pancreatic ductal adenocarcinoma 2 | 1,271
Agranulocytosis 1 | 5
Amnestic disorder 1 | 37
Anemia 1 | 252
Blepharophimosis 1 | 17
Breast cancer 1 | 3,094
Cholera 1 | 33
Coffin-Siris syndrome 1 | 17
Conduct disorder 1 | 25
Diabetic Retinopathy 1 | 53
Early myoclonic encephalopathy 1 | 8
Glottis carcinoma 1 | 2
Goodpasture syndrome 1 | 6
Gout 1 | 93
Hemolytic anemia 1 | 66
Hereditary Paraganglioma-Pheochromocytoma Syndrome 1 | 3
Hyperlysinemia 1 | 6
IGA Glomerulonephritis 1 | 454
Melanoma 1 | 261
Nasopharynx carcinoma 1 | 18
Neoplastic Syndromes, Hereditary 1 | 48
Neurofibromatosis 1 | 37
Obesity 1 | 616
PHEOCHROMOCYTOMA, SUSCEPTIBILITY TO 1 | 2
Paraganglioma 1 | 12
Peripheral vascular disease 1 | 90
Persistent generalized lymphadenopathy 1 | 15
Phaeochromocytoma 1 | 20
Pheochromocytoma 1 | 22
Pick disease 1 | 1,893
Polycystic Ovary Syndrome 1 | 332
Retinal disease 1 | 16
Sickle cell anemia 1 | 35
Sinusitis 1 | 30
Spinal muscular atrophy 1 | 24
Stomach Neoplasms 1 | 282
Thalassemia 1 | 46
Von Hippel-Lindau disease 1 | 11
Weight Gain 1 | 87
X-linked nonsyndromic deafness 1 | 10
active Crohn's disease 1 | 918
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
aldosterone-producing adenoma 1 | 664
atypical teratoid/rhabdoid tumor 1 | 1,095
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,475
cutaneous lupus erythematosus 1 | 1,056
diabetes mellitus 1 | 1,663
ductal carcinoma in situ 1 | 1,745
facioscapulohumeral dystrophy 1 | 286
fibroadenoma 1 | 557
interstitial cystitis 1 | 2,299
juvenile dermatomyositis 1 | 1,189
lung adenocarcinoma 1 | 2,713
non diabetic and post-ischemic heart failure 1 | 200
non-small cell lung cancer 1 | 2,798
non-small cell lung carcinoma 1 | 413
oligodendroglioma 1 | 2,849
pancreatic cancer 1 | 2,300
progressive supranuclear palsy 1 | 674
sonic hedgehog group medulloblastoma 1 | 1,482
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,557
tuberculosis and treatment for 6 months 1 | 686
type II diabetes mellitus and post-ischemic heart failure 1 | 89
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 18 | 17,995
Cardiovascular System 18 | 17,958
Digestive Tract 18 | 18,473
Endocrine System 18 | 18,512
Female tissues 18 | 18,647
Liver and Pancreas 18 | 18,136
Male tissues 18 | 17,969
Nervous System 18 | 18,561
Respiratory system 18 | 17,484
Skin and soft tissues 18 | 18,115
Urinary Tract 18 | 18,444

Target Family

Non-IDG 10 | 11,971
Enzyme 4 | 4,146
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 406

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 127 TMEM127 Tbio Non-IDG -1.21612 16.9 25
Histone deacetylase complex subunit SAP130 SAP130 Tdark Enzyme 0.00000 112
DNA fragmentation factor subunit beta DFFB Tbio Non-IDG -1.79288 58.1 330
Collagen type IV alpha-3-binding protein COL4A3BP Tbio Non-IDG -1.80334 59.2 247
HBS1-like protein HBS1L Tbio Non-IDG -2.49189 316.2 144
Discoidin, CUB and LCCL domain-containing protein 2 DCBLD2 Tbio Non-IDG -1.04873 13.1 149
Diphthine--ammonia ligase DPH6 Tdark Enzyme -0.39545 3.06 13
Out at first protein homolog OAF Tbio Non-IDG -1.76037 56.7 53
Alpha-protein kinase 1 ALPK1 Tbio Kinase -0.82399 10.1 54
Armadillo repeat-containing protein 7 ARMC7 Tdark Non-IDG 0.00000 1.00 35