Development Level

Tbio 7 | 10,625
Tdark 2 | 7,003

IMPC Term

decreased KLRG1-positive NK ce... 9 | 9
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 5 | 8,484
astrocytic glioma 4 | 2,241
atypical teratoid / rhabdoid tumor 4 | 4,369
glioblastoma 4 | 5,572
psoriasis 4 | 6,685
active Crohn's disease 3 | 918
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
lung adenocarcinoma 3 | 2,713
nasopharyngeal carcinoma 3 | 1,056
osteosarcoma 3 | 7,933
primitive neuroectodermal tumor 3 | 3,031
Breast cancer 2 | 3,094
Cancer 2 | 2,346
Carcinoma 2 | 2,147
Intellectual disability 2 | 573
Pick disease 2 | 1,893
adult high grade glioma 2 | 2,148
group 3 medulloblastoma 2 | 2,254
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung cancer 2 | 4,466
lung carcinoma 2 | 2,844
medulloblastoma, large-cell 2 | 6,234
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
pilocytic astrocytoma 2 | 3,086
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 1,530
ulcerative colitis 2 | 2,087
Adenoiditis 1 | 5
Atopic dermatitis 1 | 944
Azoospermia 1 | 89
Birk-Barel syndrome 1 | 2
Blood pressure finding 1 | 56
Cholangiocarcinoma 1 | 32
Congenital hypothyroidism 1 | 20
Conversion disorder 1 | 7
Gaucher disease type 1 1 | 171
Glaucoma 1 | 134
Goiter 1 | 27
Hypothyroidism 1 | 89
Large intestine cancer 1 | 12
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 13 1 | 1
Mesothelioma 1 | 40
Microcephaly 1 | 149
Multiple myeloma 1 | 1,327
Nevi and Melanomas 1 | 1
Renal Cell Carcinoma 1 | 199
Rheumatoid Arthritis 1 | 1,160
Systemic arterial pressure 1 | 56
TUMOR PREDISPOSITION SYNDROME 1 | 1
Thymoma 1 | 16
Thyroid Dyshormonogenesis 5 1 | 1
Type 2 diabetes mellitus 1 | 189
Uveal melanoma 1 | 17
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
astrocytoma 1 | 1,493
ductal carcinoma in situ 1 | 1,745
ependymoma 1 | 2,514
facioscapulohumeral dystrophy 1 | 286
gastric carcinoma 1 | 832
head and neck cancer 1 | 270
invasive ductal carcinoma 1 | 2,950
juvenile dermatomyositis 1 | 1,189
non primary Sjogren syndrome sicca 1 | 840
non-small cell lung carcinoma 1 | 413
progressive supranuclear palsy 1 | 674
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,557
tuberculosis and treatment for 6 months 1 | 686
uncontrolled asthma 1 | 67
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 9 | 17,995
Cardiovascular System 9 | 17,958
Digestive Tract 9 | 18,473
Endocrine System 9 | 18,512
Female tissues 9 | 18,647
Liver and Pancreas 9 | 18,136
Male tissues 9 | 17,969
Nervous System 9 | 18,561
Respiratory system 9 | 17,484
Skin and soft tissues 9 | 18,115
Urinary Tract 9 | 18,444

Target Family

Non-IDG 5 | 11,971
Enzyme 4 | 4,146

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polypeptide N-acetylgalactosaminyltransferase 18 GALNT18 Tdark Enzyme -0.28065 3.03 33
XK-related protein 2 XKRX Tdark Non-IDG -0.38492 2.41 56
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 BNIP2 Tbio Non-IDG -1.54032 32.4 212
Trafficking protein particle complex subunit 9 TRAPPC9 Tbio Non-IDG -2.11677 133.3 71
RNA-binding motif protein, X chromosome RBMX Tbio Non-IDG -1.49809 32.8 82
Dual oxidase maturation factor 2 DUOXA2 Tbio Enzyme -1.27171 17.0 74
Ubiquitin carboxyl-terminal hydrolase BAP1 BAP1 Tbio Enzyme -1.97152 107.2 280
GDP-mannose 4,6 dehydratase GMDS Tbio Enzyme -2.00846 105.0 102
CCR4-NOT transcription complex subunit 4 CNOT4 Tbio Non-IDG -2.62007 387.7 328