Development Level

Tbio 5 | 11,651
Tchem 1 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

decreased CD8-positive, alpha-... 8 | 8
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 7 | 11,493
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
Pick disease 3 | 1,894
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Crohn's disease 2 | 321
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
fibroadenoma 2 | 559
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
ulcerative colitis 2 | 1,819
Abnormalities, Multiple 1 | 13
Alcohol abuse 1 | 50
Alcohol dependence 1 | 107
Alcoholic Intoxication 1 | 34
Alcoholic Intoxication, Chronic 1 | 289
Alcoholism 1 | 45
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Amyotrophic lateral sclerosis type 8 1 | 10
Astrocytoma, Pilocytic 1 | 3,081
Atrichia with papular lesions 1 | 9
Batten disease 1 | 13
Bipolar Disorder 1 | 666
Bleeding tendency 1 | 37
Brain infarction 1 | 22
Breast Neoplasms 1 | 445
Cellulitis 1 | 20
Colorectal Neoplasms 1 | 243
Complications of Diabetes Mellitus 1 | 5
Coronary artery disease 1 | 268
Diabetes Complications 1 | 6
Ebstein anomaly 1 | 16
Endometriosis 1 | 540
Enterocolitis, Necrotizing 1 | 17
Esophageal Neoplasms 1 | 69
Esophageal Squamous Cell Carcinoma 1 | 77
Flushing 1 | 60
Heart Injuries 1 | 3
Heroin dependence 1 | 30
Infertility, Male 1 | 46
Intracranial aneurysm 1 | 24
Keratoconus 1 | 113
Kidney cancer 1 | 2,613
Kidney disease 1 | 430
Li-Fraumeni syndrome 1 | 13
Liver Cirrhosis, Experimental 1 | 769
Liver disease 1 | 237
Male infertility 1 | 206
Mammary Neoplasms 1 | 425
Mitral valve insufficiency 1 | 49
Mitral valve prolapse 1 | 14
Necrotizing Enterocolitis 1 | 17
Osteochondrosis 1 | 17
Precancerous Conditions 1 | 80
Prostate cancer 1 | 175
Reflex sympathetic dystrophy 1 | 7
Squamous cell carcinoma of esophagus 1 | 77
Substance abuse 1 | 59
Succinic semialdehyde dehydrogenase deficiency 1 | 16
Vascular Diseases 1 | 16
Vomiting 1 | 116
Werner syndrome 1 | 29
Wernicke-Korsakoff syndrome 1 | 10
adrenocortical carcinoma 1 | 1,428
chronic kidney disease 1 | 90
chronic lymphosyte leukemia 1 | 204
cystic fibrosis 1 | 1,696
esophageal cancer 1 | 22
gastric carcinoma 1 | 807
inclusion-cell disease 1 | 16
juvenile dermatomyositis 1 | 1,187
limb girdle muscular dystrophy 2B 1 | 40
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 4 | 4,145
GPCR 1 | 408
Non-IDG 1 | 12,091
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear receptor subfamily 1 group D member 2 NR1D2 Tbio Nuclear Receptor -1.77473 57.5 205
Probable threonine protease PRSS50 PRSS50 Tbio Enzyme -1.83072 69.2 99
Protein FAM234B FAM234B Tdark Non-IDG 1.00 0.10 21
Lysosomal acid phosphatase ACP2 Tbio Enzyme -2.38317 237.0 83
ATPase WRNIP1 WRNIP1 Tbio Enzyme -2.55209 340.4 166
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -1.07328 11.4 100
G-protein coupled estrogen receptor 1 GPER1 Tchem GPCR -2.78141 706.4 288
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470