Development Level

Tbio 5 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

cyanosis 7 | 7
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 7 | 11,493
ovarian cancer 6 | 8,520
osteosarcoma 5 | 7,950
Kidney cancer 4 | 2,613
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
Neurodegenerative disease 3 | 414
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
lung cancer 3 | 4,740
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Babinski Reflex 2 | 100
Congenital pes cavus 2 | 88
Congestive heart failure 2 | 113
Decreased tendon reflex 2 | 122
Distal sensory impairment 2 | 52
Epilepsy 2 | 792
Heart failure 2 | 162
Hyperhidrosis disorder 2 | 81
Increased sweating 2 | 81
Monoparesis - leg 2 | 27
Neuropathy 2 | 261
Rheumatoid arthritis 2 | 1,191
Sweating 2 | 81
Weakness of lower limb 2 | 27
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
facioscapulohumeral dystrophy 2 | 288
group 3 medulloblastoma 2 | 4,104
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
Acute coronary syndrome 1 | 39
Bamforth-Lazarus syndrome 1 | 4
Behavioral variant of frontotemporal dementia 1 | 8
Cleft lip and alveolus 1 | 4
Compulsive hoarding 1 | 7
Dentin dysplasia 1 | 19
Developmental absence of tooth 1 | 7
Developmental arithmetic disorder 1 | 8
Dysphasia 1 | 23
Echolalia 1 | 12
Episodic ataxia type 1 1 | 4
Excess nuchal skin 1 | 30
Familial isolated dilated cardiomyopathy 1 | 41
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Graves Disease 1 | 11
HYPOKALEMIC PERIODIC PARALYSIS, TYPE 1 1 | 2
Hyperkalemia, diminished renal excretion 1 | 2
Hyperorality 1 | 7
Hyperphagia 1 | 23
Hypodontia and nail dysgenesis 1 | 1
Hypokalemic periodic paralysis 1 1 | 2
Hypoplastic deciduous teeth 1 | 1
Hypoplastic enamel-onycholysis-hypohidrosis syndrome 1 | 1
Increased appetite (finding) 1 | 23
Koilonychia 1 | 7
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
MALIGNANT HYPERTHERMIA, SUSCEPTIBILITY TO, 5 1 | 1
Malignant hyperpyrexia due to anesthesia 1 | 10
Malignant hyperthermia susceptibility type 5 1 | 1
Memory Disorders 1 | 40
Microdontia of primary teeth 1 | 1
Missing more than six teeth 1 | 22
Muscular stiffness 1 | 12
Neurodegenerative Diseases 1 | 38
OROFACIAL CLEFT 5 1 | 1
Paroxysmal supraventricular tachycardia 1 | 12
Peg-shaped teeth 1 | 8
Pointed teeth 1 | 8
Prevention of Paroxysmal Supraventricular Tachycardia 1 | 4
Primitive reflexes (palmomental, snout, glabellar) 1 | 7
Prinzmetal angina 1 | 6
Restrictive behavior, interests, and activities 1 | 7
Ridged fingernails 1 | 4
THYROTOXIC PERIODIC PARALYSIS, SUSCEPTIBILITY TO, 1 1 | 2
Thin toenails 1 | 1
Thyrotoxic periodic paralysis 1 | 3
Thyrotoxicosis with toxic single thyroid nodule 1 | 2
Tooth Agenesis, Familial 1 | 1
Tooth Agenesis, Selective, 1 1 | 2
Tooth and nail syndrome 1 | 1
Toxic multinodular goiter 1 | 2
Transient hypophosphatemia 1 | 2
Witkop syndrome 1 | 1

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Liver and Pancreas 6 | 16,750
Cardiovascular System 5 | 15,192

Target Family

Non-IDG 4 | 12,091
Enzyme 1 | 4,145
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Kinesin heavy chain isoform 5A KIF5A Tbio Non-IDG -1.69131 48.4 170
Bcl-2-associated transcription factor 1 BCLAF1 Tbio Non-IDG -2.29538 190.0 210
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S Tclin Ion Channel -2.21321 163.9 114
Cingulin CGN Tbio Non-IDG -1.87353 73.7 58
Kinesin-like protein KIF1B KIF1B Tbio Non-IDG -2.08306 118.0 60