Development Level

Tbio 5 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

corneal vascularization 6 | 6
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 5 | 11,493
ependymoma 3 | 4,679
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
Kidney cancer 2 | 2,613
atypical teratoid / rhabdoid tumor 2 | 5,112
atypical teratoid/rhabdoid tumor 2 | 357
cystic fibrosis 2 | 1,696
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
ovarian cancer 2 | 8,520
spina bifida 2 | 1,074
Adult onset 1 | 82
Afro-textured hair 1 | 13
Agranulocytosis 1 | 6
Anorexia nervosa 1 | 80
Arrhythmogenic Right Ventricular Dysplasia, Familial, 11 1 | 1
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Atrophy of cerebellum 1 | 103
Autosomal dominant cerebellar ataxia 1 | 33
Autosomal recessive predisposition 1 | 1,442
Bipolar Disorder 1 | 666
Breast cancer 1 | 3,578
Cardiomyopathy 1 | 116
Cardiomyopathy, right ventricular 1 | 7
Cerebellar degeneration 1 | 103
Chemical and Drug Induced Liver Injury 1 | 195
Choroid Plexus Papilloma 1 | 10
Crohn's disease 1 | 321
Dilated cardiomyopathy 1 | 56
Dyspnea 1 | 76
Gait, Unsteady 1 | 29
Hypertension 1 | 396
Hypertensive disease 1 | 292
Infratentorial atrophy 1 | 103
Intellectual disability 1 | 1,016
Kinky hair texture 1 | 13
Lymphopenia 1 | 67
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 1 | 16
Microcephalic osteodysplastic primordial dwarfism type II 1 | 13
Microcephaly 1 | 166
Microcephaly 1, Primary, Autosomal Recessive 1 | 2
Nappy hair texture 1 | 13
Neurodegenerative disease 1 | 414
Palmoplantar keratosis 1 | 74
Palpitations 1 | 18
Pemphigus 1 | 23
Premature chromosome condensation with microcephaly and intellectual disability 1 | 1
Progressive disorder 1 | 142
Rheumatoid arthritis 1 | 1,191
SPINOCEREBELLAR ATAXIA 41 1 | 1
Seckel syndrome 1 | 34
Sialolithiasis 1 | 2
Spinocerebellar Ataxias 1 | 34
Spinocerebellar ataxia type 14 1 | 1
Sudden Cardiac Death 1 | 29
Syncope 1 | 22
Ventricular arrhythmia 1 | 27
Wooly hair 1 | 17
X-linked dystonia-parkinsonism 1 | 9
active ulcerative colitis 1 | 764
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
cutaneous lupus erythematosus 1 | 1,057
ductal carcinoma in situ 1 | 1,745
group 4 medulloblastoma 1 | 1,855
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
mucosa-associated lymphoid tissue lymphoma 1 | 484
pediatric high grade glioma 1 | 1,064
periodontitis 1 | 293
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Non-IDG 4 | 12,091
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Short transient receptor potential channel 3 TRPC3 Tchem Ion Channel -2.46704 294.6 217
Microcephalin MCPH1 Tbio Non-IDG -1.96863 109.3 260
Desmocollin-2 DSC2 Tbio Non-IDG -1.89689 79.7 173
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.42853 26.4 88
Homeobox protein BarH-like 2 BARX2 Tbio Transcription Factor -1.17761 19.7 66
Cysteine-rich protein 2-binding protein KAT14 Tbio Non-IDG -0.90082 7.81 111