Development Level

Tbio 28 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

corneal opacity 32 | 32
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 25 | 11,493
osteosarcoma 16 | 7,950
ovarian cancer 15 | 8,520
medulloblastoma, large-cell 12 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
primitive neuroectodermal tumor 11 | 3,035
glioblastoma 10 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
psoriasis 10 | 6,694
Pick disease 9 | 1,894
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
lung cancer 9 | 4,740
Astrocytoma, Pilocytic 8 | 3,081
Cancer 8 | 2,499
lung carcinoma 8 | 2,843
Kidney cancer 7 | 2,613
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
pediatric high grade glioma 7 | 1,064
spina bifida 7 | 1,074
Breast cancer 6 | 3,578
Intellectual disability 6 | 1,016
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
lung adenocarcinoma 6 | 2,716
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
ulcerative colitis 6 | 1,819
Anemia 5 | 365
Rheumatoid arthritis 5 | 1,191
cystic fibrosis 5 | 1,696
interstitial cystitis 5 | 2,312
primary pancreatic ductal adenocarcinoma 5 | 1,109
Atopic dermatitis 4 | 952
Autosomal recessive predisposition 4 | 1,442
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
juvenile dermatomyositis 4 | 1,187
pituitary cancer 4 | 1,972
Bipolar Disorder 3 | 666
Down syndrome 3 | 499
Liver cancer 3 | 604
Multiple myeloma 3 | 1,332
active ulcerative colitis 3 | 764
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
group 4 medulloblastoma 3 | 1,855
pancreatic carcinoma 3 | 562
progressive supranuclear palsy 3 | 676
tuberculosis and treatment for 6 months 3 | 409
Alzheimer's disease 2 | 658
Autistic Disorder 2 | 364
Chemical and Drug Induced Liver Injury 2 | 195
Cognitive delay 2 | 608
Congenital deafness 2 | 185
Congenital heart disease 2 | 93
Craniofacial Abnormalities 2 | 151
Craniosynostosis 2 | 74
Deafness 2 | 198
Depressive disorder 2 | 409
Disease of anatomical entity 2 | 32
Duchenne muscular dystrophy 2 | 601
Dull intelligence 2 | 645
Dyspnea 2 | 76
Fanconi anemia 2 | 56
Global developmental delay 2 | 608
Hearing Loss, Partial 2 | 185
Low intelligence 2 | 645
Mental Depression 2 | 333
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Muscle Spasticity 2 | 195
Polycythemia vera 2 | 27
Poor school performance 2 | 645
Prostate cancer 2 | 175
Thrombocytopenia 2 | 197
Thrombocytosis 2 | 38
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
gastric cancer 2 | 459
hearing impairment 2 | 199
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
posterior fossa group B ependymoma 2 | 416
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 162
tuberculosis 2 | 2,010
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Male tissues 32 | 17,142
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678
Blood and immune system 31 | 16,909
Respiratory system 31 | 16,393
Cardiovascular System 30 | 15,192
Nervous System 30 | 16,725

Target Family

Non-IDG 16 | 12,091
Enzyme 10 | 4,145
Transcription Factor 4 | 1,400
Epigenetic 2 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.98202 97.3 170
Ras-related protein Rab-19 RAB19 Tdark Enzyme -0.54731 3.31 75
E3 ubiquitin-protein ligase FANCL FANCL Tbio Enzyme -2.46302 286.2 146
Protocadherin-18 PCDH18 Tbio Non-IDG -0.69395 5.31 87
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.42853 26.4 88
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.83079 8.71 94
Peptidyl-prolyl cis-trans isomerase FKBP5 FKBP5 Tchem Enzyme -2.52114 348.1 299
Protein Shroom4 SHROOM4 Tbio Non-IDG -0.60096 4.12 8