Development Level

Tbio 69 | 11,178
Tdark 10 | 6,569
Tchem 9 | 1,885
Tclin 4 | 612

IMPC Phenotype

cataract 92 | 92
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 53 | 11,192
ovarian cancer 49 | 8,297
medulloblastoma, large-cell 40 | 6,086
osteosarcoma 40 | 7,766
glioblastoma 39 | 5,635
lung cancer 38 | 4,607
atypical teratoid / rhabdoid tumor 34 | 4,971
psoriasis 33 | 6,514
Breast cancer 28 | 3,469
adult high grade glioma 27 | 3,701
ependymoma 26 | 4,559
group 3 medulloblastoma 26 | 4,002
interstitial cystitis 24 | 2,237
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,902
Astrocytoma, Pilocytic 22 | 3,006
pancreatic cancer 22 | 2,322
primitive neuroectodermal tumor 22 | 2,957
malignant mesothelioma 21 | 3,135
astrocytic glioma 20 | 2,530
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,204
Cancer 19 | 2,388
adrenocortical carcinoma 19 | 1,385
non-small cell lung cancer 19 | 2,799
invasive ductal carcinoma 18 | 2,867
lung adenocarcinoma 18 | 2,627
lung carcinoma 18 | 2,755
oligodendroglioma 16 | 2,768
pituitary cancer 16 | 1,915
subependymal giant cell astrocytoma 16 | 2,230
Autosomal recessive predisposition 15 | 1,407
Kidney cancer 15 | 2,548
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,911
diabetes mellitus 14 | 1,683
ulcerative colitis 13 | 1,765
Multiple myeloma 12 | 1,296
Pick disease 12 | 1,856
cutaneous lupus erythematosus 12 | 1,016
ductal carcinoma in situ 12 | 1,686
tuberculosis 12 | 1,963
group 4 medulloblastoma 11 | 1,806
cystic fibrosis 10 | 1,629
esophageal adenocarcinoma 10 | 696
juvenile dermatomyositis 10 | 1,147
nasopharyngeal carcinoma 10 | 1,024
Epilepsy 9 | 775
colon cancer 9 | 1,428
pediatric high grade glioma 9 | 1,035
Short stature 8 | 514
Waldenstrons macroglobulinemia 8 | 742
breast carcinoma 8 | 1,589
gastric carcinoma 8 | 781
Duchenne muscular dystrophy 7 | 587
Endometriosis 7 | 521
Liver Cirrhosis, Experimental 7 | 733
Schizophrenia 7 | 1,136
active ulcerative colitis 7 | 736
astrocytoma 7 | 1,113
non primary Sjogren syndrome sicca 7 | 861
Alzheimer's disease 6 | 640
Atopic dermatitis 6 | 915
Intellectual disability 6 | 998
Seizures 6 | 584
acute quadriplegic myopathy 6 | 1,133
aldosterone-producing adenoma 6 | 646
pancreatic carcinoma 6 | 555
spina bifida 6 | 1,053
Atherosclerosis 5 | 276
Breast Neoplasms 5 | 423
Chronic Lymphocytic Leukemia 5 | 254
Cognitive delay 5 | 596
Fetal Growth Retardation 5 | 186
Global developmental delay 5 | 596
Mammary Neoplasms 5 | 403
Melanoma 5 | 689
Mental and motor retardation 5 | 596
Muscle hypotonia 5 | 562
Rheumatoid arthritis 5 | 1,156
Small head 5 | 366
active Crohn's disease 5 | 882
dermatomyositis 5 | 941
head and neck cancer and chronic obstructive pulmonary disease 5 | 226
posterior fossa group A ependymoma 5 | 456
posterior fossa group B ependymoma 5 | 406
primary Sjogren syndrome 5 | 710
primary pancreatic ductal adenocarcinoma 5 | 1,071
Bipolar Disorder 4 | 646
Down syndrome 4 | 480
Dull intelligence 4 | 634
Hepatomegaly 4 | 280
Intrauterine retardation 4 | 174
Low intelligence 4 | 634
Mental deficiency 4 | 634
Poor school performance 4 | 634
acute myeloid leukemia 4 | 760
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 492
hepatocellular carcinoma 4 | 536
limb girdle muscular dystrophy 2A 4 | 208
periodontitis 4 | 280
sonic hedgehog group medulloblastoma 4 | 459

Tissue

Digestive Tract 90 | 17,369
Blood and immune system 89 | 16,909
Endocrine System 89 | 18,159
Female tissues 89 | 17,400
Liver and Pancreas 89 | 16,750
Male tissues 88 | 17,142
Skin and soft tissues 88 | 17,230
Respiratory system 87 | 16,393
Nervous System 86 | 16,725
Urinary Tract 86 | 16,678
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 26 | 4,145
Transporter 4 | 473
Kinase 3 | 634
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
tRNA methyltransferase 10 homolog A TRMT10A Tbio Enzyme -1.10123 12.2 75
Ras-related protein Rab-35 RAB35 Tbio Enzyme -1.61645 42.9 224
Fatty acid-binding protein, heart FABP3 Tchem Non-IDG -3.02325 1104.3 734
Ribosome biogenesis protein BMS1 homolog BMS1 Tbio Non-IDG -1.44213 28.2 53
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272
Tubulin-specific chaperone E TBCE Tbio Non-IDG -2.37521 233.9 118
Semaphorin-3F SEMA3F Tbio Non-IDG -1.97011 94.5 125
Centromere-associated protein E CENPE Tchem Non-IDG -2.14817 140.2 166
Corneodesmosin CDSN Tbio Non-IDG -3.23661 1709.5 0
E3 ubiquitin ligase RNF157 RNF157 Tbio Non-IDG 0.11 1.20 96