Development Level

Tbio 71 | 11,651
Tdark 10 | 6,593
Tchem 7 | 1,388
Tclin 4 | 612

IMPC Phenotype

cataract 92 | 92
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 53 | 11,493
ovarian cancer 49 | 8,520
medulloblastoma, large-cell 40 | 6,241
osteosarcoma 40 | 7,950
glioblastoma 39 | 5,792
lung cancer 38 | 4,740
atypical teratoid / rhabdoid tumor 34 | 5,112
psoriasis 33 | 6,694
Breast cancer 28 | 3,578
adult high grade glioma 27 | 3,801
ependymoma 26 | 4,679
group 3 medulloblastoma 26 | 4,104
interstitial cystitis 24 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
Astrocytoma, Pilocytic 22 | 3,081
pancreatic cancer 22 | 2,398
primitive neuroectodermal tumor 22 | 3,035
malignant mesothelioma 21 | 3,232
astrocytic glioma 20 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
Cancer 19 | 2,499
adrenocortical carcinoma 19 | 1,428
non-small cell lung cancer 19 | 2,890
invasive ductal carcinoma 18 | 2,951
lung adenocarcinoma 18 | 2,716
lung carcinoma 18 | 2,843
oligodendroglioma 16 | 2,850
pituitary cancer 16 | 1,972
subependymal giant cell astrocytoma 16 | 2,287
Autosomal recessive predisposition 15 | 1,442
Kidney cancer 15 | 2,613
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
diabetes mellitus 14 | 1,728
ulcerative colitis 13 | 1,819
Multiple myeloma 12 | 1,332
Pick disease 12 | 1,894
cutaneous lupus erythematosus 12 | 1,057
ductal carcinoma in situ 12 | 1,745
tuberculosis 12 | 2,010
group 4 medulloblastoma 11 | 1,855
cystic fibrosis 10 | 1,696
esophageal adenocarcinoma 10 | 737
juvenile dermatomyositis 10 | 1,187
nasopharyngeal carcinoma 10 | 1,058
Epilepsy 9 | 792
colon cancer 9 | 1,478
pediatric high grade glioma 9 | 1,064
Short stature 8 | 531
Waldenstrons macroglobulinemia 8 | 765
breast carcinoma 8 | 1,638
gastric carcinoma 8 | 807
Duchenne muscular dystrophy 7 | 601
Endometriosis 7 | 540
Liver Cirrhosis, Experimental 7 | 769
Schizophrenia 7 | 1,160
active ulcerative colitis 7 | 764
astrocytoma 7 | 1,146
non primary Sjogren syndrome sicca 7 | 891
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Intellectual disability 6 | 1,016
Seizures 6 | 596
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
pancreatic carcinoma 6 | 562
spina bifida 6 | 1,074
Atherosclerosis 5 | 291
Breast Neoplasms 5 | 445
Chronic Lymphocytic Leukemia 5 | 262
Cognitive delay 5 | 608
Fetal Growth Retardation 5 | 189
Global developmental delay 5 | 608
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Mental and motor retardation 5 | 608
Muscle hypotonia 5 | 571
Rheumatoid arthritis 5 | 1,191
Small head 5 | 374
active Crohn's disease 5 | 922
dermatomyositis 5 | 966
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
posterior fossa group A ependymoma 5 | 468
posterior fossa group B ependymoma 5 | 416
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
Bipolar Disorder 4 | 666
Down syndrome 4 | 499
Dull intelligence 4 | 645
Hepatomegaly 4 | 285
Intrauterine retardation 4 | 176
Low intelligence 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
acute myeloid leukemia 4 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
hepatocellular carcinoma 4 | 547
limb girdle muscular dystrophy 2A 4 | 213
periodontitis 4 | 293
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Digestive Tract 90 | 17,369
Blood and immune system 89 | 16,909
Endocrine System 89 | 18,159
Female tissues 89 | 17,400
Liver and Pancreas 89 | 16,750
Male tissues 88 | 17,142
Skin and soft tissues 88 | 17,230
Respiratory system 87 | 16,393
Nervous System 86 | 16,725
Urinary Tract 86 | 16,678
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 26 | 4,145
Transporter 4 | 473
Kinase 3 | 634
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Yae1 domain-containing protein 1 YAE1D1 Tdark Non-IDG 0.26 0.54 89
Nuclear receptor subfamily 1 group D member 2 NR1D2 Tbio Nuclear Receptor -1.77473 57.5 205
Dynactin subunit 5 DCTN5 Tdark Non-IDG -0.32495 0.71 53
5'-AMP-activated protein kinase subunit beta-1 PRKAB1 Tbio Kinase -1.52519 32.5 532
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164
Protein regulator of cytokinesis 1 PRC1 Tbio Non-IDG -0.99763 6.30 172
MAU2 chromatid cohesion factor homolog MAU2 Tdark Non-IDG -2.03797 96.6 32
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 ST6GALNAC3 Tbio Enzyme -0.89030 6.75 34
Geranylgeranyl pyrophosphate synthase GGPS1 Tchem Enzyme -2.30083 190.0 301
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201