Development Level

Tbio 24 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

anophthalmia 33 | 33
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 22 | 11,493
ovarian cancer 20 | 8,520
osteosarcoma 15 | 7,950
group 3 medulloblastoma 8 | 4,104
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
psoriasis 7 | 6,694
Cancer 6 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
ulcerative colitis 6 | 1,819
Breast cancer 5 | 3,578
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Mental and motor retardation 5 | 608
Rheumatoid arthritis 5 | 1,191
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
dermatomyositis 5 | 966
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Autosomal recessive predisposition 4 | 1,442
acute myeloid leukemia 4 | 783
adult high grade glioma 4 | 3,801
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
Dull intelligence 3 | 645
Epilepsy 3 | 792
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Microcephaly 3 | 166
Muscle hypotonia 3 | 571
Poor school performance 3 | 645
Seizures 3 | 596
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Anemia 2 | 365
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Cerebral atrophy 2 | 178
Cervical cancer 2 | 24
Chronic obstructive pulmonary disease 2 | 184
Cleft Lip 2 | 141
Colorectal Neoplasms 2 | 243
Decreased platelet count 2 | 111
Disease Progression 2 | 136
Esophageal atresia with or without tracheoesophageal fistula 2 | 21
Failure to gain weight 2 | 365
Fanconi anemia 2 | 56
Feeding difficulties in infancy 2 | 175
Infantile onset 2 | 238
Low compliance bladder 2 | 11
Microphthalmia 2 | 76
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Proteinuria 2 | 144
Schizophrenia 2 | 1,160
Short palpebral fissure 2 | 38
Small head 2 | 374
Stomach Neoplasms 2 | 300
Thrombocytopenia 2 | 197
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
chronic rhinosinusitis 2 | 512
diabetes mellitus 2 | 1,728
esophageal atresia/tracheoesophageal fistula 2 | 22
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
inflammatory breast cancer 2 | 286
interstitial lung disease 2 | 298
non primary Sjogren syndrome sicca 2 | 891
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 6 months 2 | 409
Anorexia 1 | 43
CATARACT 16, MULTIPLE TYPES 1 | 15
Cloudy cornea 1 | 33
Corneal stromal opacities 1 | 33
Epidermodysplasia verruciformis 1 | 21
Nephrotic Syndrome 1 | 78
Tracheoesophageal Fistula 1 | 36

Tissue

Digestive Tract 32 | 17,369
Male tissues 32 | 17,142
Skin and soft tissues 32 | 17,230
Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Urinary Tract 31 | 16,678

Target Family

Non-IDG 17 | 12,091
Enzyme 9 | 4,145
Kinase 3 | 634
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Metal regulatory transcription factor 1 MTF1 Tbio Transcription Factor -1.98140 101.0 135
Cell surface A33 antigen GPA33 Tbio Non-IDG -1.79665 56.9 248
E3 ubiquitin-protein ligase FANCL FANCL Tbio Enzyme -2.46302 286.2 146
Methylmalonic aciduria and homocystinuria type C protein MMACHC Tbio Non-IDG -1.83573 76.5 233
Sodium-dependent lysophosphatidylcholine symporter 1 MFSD2A Tbio Non-IDG -1.40175 26.3 73
Nucleoredoxin NXN Tbio Non-IDG -2.54390 345.4 96
Matrix metalloproteinase-15 MMP15 Tchem Enzyme -1.69065 43.4 351
Volume-regulated anion channel subunit LRRC8A LRRC8A Tbio Non-IDG -1.55179 39.4 129
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27