Development Level

Tbio 7 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

absent vibrissae 12 | 12
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
Astrocytoma, Pilocytic 7 | 3,081
glioblastoma 7 | 5,792
psoriasis 7 | 6,694
adult high grade glioma 6 | 3,801
ulcerative colitis 6 | 1,819
Breast cancer 5 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
lung carcinoma 5 | 2,843
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
Cancer 3 | 2,499
adrenocortical carcinoma 3 | 1,428
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Barrett's esophagus 2 | 182
Duchenne muscular dystrophy 2 | 601
Rheumatoid arthritis 2 | 1,191
acute myeloid leukemia 2 | 783
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sonic hedgehog group medulloblastoma 2 | 467
Arthritis, Rheumatoid 1 | 174
Atopic dermatitis 1 | 952
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
Autosomal dominant nonsyndromic deafness 25 1 | 6
Breast Neoplasms 1 | 445
Brown-Vialetto-Van Laere syndrome 1 | 5
Bruxism 1 | 18
Calcinosis 1 | 70
Celiac disease 1 | 116
Chagas disease 1 | 39
Chemical and Drug Induced Liver Injury 1 | 195
Colorectal Neoplasms 1 | 243
Congenital stationary night blindness 1 | 29
Coronary artery disease 1 | 268
Epilepsy 1 | 792
Essential Hypertension 1 | 94
Eye and adnexa disease 1 | 18
FNAITP 1 | 6
Fatty Liver 1 | 70
Gaucher disease type 1 1 | 180
Gingival recession 1 | 13
Heart Valve Diseases 1 | 25
Heart valve disease 1 | 39
Hypertension 1 | 396
Kidney cancer 1 | 2,613
Lymphangioma 1 | 9
Lymphedema 1 | 42
MALT lymphoma 1 | 6
Macular degeneration 1 | 65
Mammary Neoplasms 1 | 425
Memory Disorders 1 | 40
Mesothelioma, Malignant 1 | 105
Multiple myeloma 1 | 1,332
Ovarian Cysts 1 | 41
Parkinson's disease 1 | 392
Photosensitive trichothiodystrophy 1 | 30
Refsum disease 1 | 20
Rhizomelic chondrodysplasia punctata 1 | 11
Schnyder Corneal Dystrophy 1 | 23
Sensorineural hearing loss 1 | 106
Thrombocytopenia 1 | 197
Zellweger syndrome 1 | 37
active Crohn's disease 1 | 922
acute quadriplegic myopathy 1 | 1,158
atypical teratoid/rhabdoid tumor 1 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
gastric carcinoma 1 | 807
ileal Crohn's disease 1 | 9
medulloblastoma 1 | 720
nasopharyngeal carcinoma 1 | 1,058
non-inflammatory breast cancer 1 | 66
posterior fossa group B ependymoma 1 | 416
spina bifida 1 | 1,074

Tissue

Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Skin and soft tissues 12 | 17,230
Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Urinary Tract 11 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 6 | 12,091
Transcription Factor 2 | 1,400
Transporter 2 | 473
GPCR 1 | 408
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Probable G-protein coupled receptor 34 GPR34 Tchem GPCR -1.31197 21.9 204
Calcium uniporter regulatory subunit MCUb, mitochondrial MCUB Tdark Non-IDG -0.76467 3.88 57
Homeobox protein BarH-like 2 BARX2 Tbio Transcription Factor -1.17761 19.7 66
Plasma membrane calcium-transporting ATPase 1 ATP2B1 Tbio Transporter -2.01694 100.0 110
RIIa domain-containing protein 1 RIIAD1 Tdark Non-IDG 0.00000 14
DOMON domain-containing protein FRRS1L FRRS1L Tbio Non-IDG -1.59651 36.0 58
Solute carrier family 52, riboflavin transporter, member 2 SLC52A2 Tbio Transporter -1.42102 23.2 37
Receptor-interacting serine/threonine-protein kinase 3 RIPK3 Tchem Kinase -2.22748 161.7 603
Podoplanin PDPN Tbio Non-IDG -3.34579 2142.9 847